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. Cervical metastases from an occult primary site . Semin Surg Oncol 1991 ; 7 : 2 – 8 . 5. Issing WJ Taleban B Tauber S . Diagnosis and management of carcinoma of unknown primary in the head and neck . Eur Arch Otorhinolaryngol 2003 ; 260

, MD • 646-888-4162 Jedd Wolchok, MD, PhD • 646-888-2395 ClinicalTrials.gov Identifier: NCT01682213 A Phase I Trial of Vorinostat Concurrent With Stereotactic Radiotherapy in Treatment of Brain Metastases From Non–Small Cell Lung Cancer

Metastases from Solid Malignancies Principal Investigator: John C. Grecula, MD Condition: Brain metastases from solid tumors Institution: The Ohio State University Comprehensive Cancer Center – James Cancer Hospital and Solove Research Institute

prognosis of TNM stage II colorectal cancer . Eur J Cancer 2005 ; 41 : 272 – 279 . 18 Newland RC Dent OF Lyttle MN . Pathologic determinants of survival associated with colorectal cancer with lymph node metastases. A multivariate analysis of

favorable-histology Wilms tumor (FHWT) and pulmonary metastases limited to the lungs that fail to resolve completely after an initial 5-week period of chemotherapy with the combination of vincristine/dactinomycin/doxorubicin, based on a comparison of the

magnification ×100). PET/CT revealed right-sided lung metastases and lymph node involvement in the right axilla. Based on the large size of the tumor and axillary lymphadenopathy, the outside institution opted to excise the SC with negative margins and

. Nat Rev Cancer 2009 ; 9 : 239 – 252 . 13 Coleman RE . Skeletal complications of malignancy . Cancer 1997 ; 80 ( 8 Suppl ): 1588 – 1594 . 14 Galasko C . The anatomy and pathways of skeletal metastases . In: Weiss L Gilbert

that “FDG-PET/CT may…be helpful in identifying unsuspected regional nodal disease and/or distant metastases when used in addition to standard imaging studies.” In the multicenter study by Hyland et al, 1 PET/CT reduced false-positive risk by half and

.gov Identifier: NCT00949325 A Phase I Trial of Vorinostat Concurrent with Stereotactic Radiotherapy in Treatment of Brain Metastases from Non–Small Cell Lung Cancer Principal Investigator: Griffith Harsh, MD Condition: Brain metastases, non

carcinoma and up to 10% of those with follicular or Hürthle cell carcinoma have tumors that aggressively invade structures in the neck or have produced distant metastases. These cancers are difficult to cure. Recurrence of Differentiated Thyroid