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David Cella, Sarah K. Rosenbloom, Jennifer L. Beaumont, Susan E. Yount, Diane Paul, Debra Hampton, Amy P. Abernethy, Paul B. Jacobsen, Karen Syrjala, and Jamie H. Von Roenn

symptoms specific to a given tumor can represent efficacy in achieving a meaningful patient outcome. Most validated measures of cancer-specific quality of life incorporate an assessment of certain prevalent symptoms, such as pain and fatigue, within a

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Efrat Dotan, Louise C. Walter, Ilene S. Browner, Katherine Clifton, Harvey Jay Cohen, Martine Extermann, Cary Gross, Sumati Gupta, Genevieve Hollis, Joleen Hubbard, Reshma Jagsi, Nancy L. Keating, Elizabeth Kessler, Thuy Koll, Beatriz Korc-Grodzicki, June M. McKoy, Sumi Misra, Dominic Moon, Tracey O’Connor, Cynthia Owusu, Ashley Rosko, Marcia Russell, Mina Sedrak, Fareeha Siddiqui, Amy Stella, Derek L. Stirewalt, Ishwaria M. Subbiah, William P. Tew, Grant R. Williams, Liz Hollinger, Giby V. George, and Hema Sundar

confounded by fatigue, depression, anxiety, underlying brain tumors, endocrine dysfunction, nutritional deficiency, alcohol use, and sleep disturbances. 50 Therefore, if dementia is suspected, further evaluation including brain imaging, neuropsychological

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Somasundaram Subramaniam, Jason A. Zell, and Pamela L. Kunz

therefore initiated therapy with everolimus. After starting everolimus he noted improvement in pain and diarrhea. He had side effects of fatigue, stomatitis, a pustular rash on his fingers and scalp, and mild thrombocytopenia. He had been on everolimus for

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Andrew J. Armstrong

men that were evaluated,” explained Dr. Armstrong. Fatigue, fall risk, and hypertension were the most common clinically relevant adverse events associated with enzalutamide treatment. 7 In fact, hypertension occurred 2 to 3 times as often with

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Thomas Olencki

SCC. A phase II study was conducted at his center, but was discontinued due to overwhelming fatigue, anorexia, weight loss, and pleural effusion. Other therapies appear to offer more promise in the treatment of cutaneous SCC. Dr. Olencki discussed

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David S. Ettinger

%, respectively. The most common side effects of nivolumab were fatigue, musculoskeletal pain, decreased appetite, cough, and constipation. Eighty-three patients had tumor samples suitable for PD-L1 expression analysis. Across the prespecified expression levels

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Michelle E. Melisko and Joseph B. Narus

not so obvious ways,” stated Dr. Melisko. For instance, adverse effects of treatment may include reduced sexual desire, decreased libido, and fatigue. In addition, “Endocrine therapy has a profound impact on both men and women,” she added. Along with

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Presenter: Stephen D. Smith

.4 months. The safety of ibrutinib in MZL is similar to that seen in other diseases. Frequently occurring adverse effects include fatigue, diarrhea, and anemia. Atrial fibrillation should be a reason for concern in patients with cardiac history, said Dr

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-Ineligible, Newly Diagnosed Multiple Myeloma In the first case study, a 75-year-old man presented with new back pain and fatigue. The patient was able to perform all activities of daily living and resided approximately 70 miles away from the treatment center

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Jennifer A. Ligibel and Crystal S. Denlinger

.” Subtopics included in the Guidelines are anxiety and depression, cognitive function, exercise, immunizations/infections, fatigue, pain, sexual function, and sleep disorders. The select subtopics presented by Drs. Ligibel and Denlinger were exercise