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NCCN Guidelines Insights: Ovarian Cancer, Version 1.2019

Featured Updates to the NCCN Guidelines

Deborah K. Armstrong, Ronald D. Alvarez, Jamie N. Bakkum-Gamez, Lisa Barroilhet, Kian Behbakht, Andrew Berchuck, Jonathan S. Berek, Lee-may Chen, Mihaela Cristea, Marie DeRosa, Adam C. ElNaggar, David M. Gershenson, Heidi J. Gray, Ardeshir Hakam, Angela Jain, Carolyn Johnston, Charles A. Leath III, Joyce Liu, Haider Mahdi, Daniela Matei, Michael McHale, Karen McLean, David M. O’Malley, Richard T. Penson, Sanja Percac-Lima, Elena Ratner, Steven W. Remmenga, Paul Sabbatini, Theresa L. Werner, Emese Zsiros, Jennifer L. Burns, and Anita M. Engh

options for maintenance therapy, all patients with histologically confirmed ovarian cancer should undergo genetic risk evaluation and BRCA1 and BRCA2 testing, if not previously performed. However, treatment should not be delayed for genetic counseling

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Current Approaches in Hereditary Nonpolyposis Colorectal Cancer

Patrick M. Lynch

reached virtually the same conclusion using a similar analytic strategy. It is further generally agreed that any practice or program that undertakes to perform MSI/IHC tumor testing must be prepared to routinely offer genetic counseling to patients with

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Molecular Tumor Testing for Lynch Syndrome in Patients With Colorectal Cancer

Jeremy Matloff, Aimee Lucas, Alexandros D. Polydorides, and Steven H. Itzkowitz

-risk individuals. Thus, any formalized process should specifically include the following steps: 1) identifying positive results; 2) contacting the physician who is responsible for the affected individuals; 3) genetic counseling and testing if available and desired

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Survivorship: Tools for Transitioning Patients With Cancer

Mary Ann Morgan and Crystal S. Denlinger

emphasize the need to know types and frequency of tests, information on what could happen, what their long-term/late needs may be, symptoms to report, and whom to call with concerns. Many have questions about genetic counseling, risks, and testing for their

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Genetic/Familial High-Risk Assessment: Breast and Ovarian, Version 2.2015

Mary B. Daly, Robert Pilarski, Jennifer E. Axilbund, Michael Berry, Saundra S. Buys, Beth Crawford, Meagan Farmer, Susan Friedman, Judy E. Garber, Seema Khan, Catherine Klein, Wendy Kohlmann, Allison Kurian, Jennifer K. Litton, Lisa Madlensky, P. Kelly Marcom, Sofia D. Merajver, Kenneth Offit, Tuya Pal, Huma Rana, Gwen Reiser, Mark E. Robson, Kristen Mahoney Shannon, Elizabeth Swisher, Nicoleta C. Voian, Jeffrey N. Weitzel, Alison Whelan, Myra J. Wick, Georgia L. Wiesner, Mary Dwyer, Rashmi Kumar, and Susan Darlow

applying these guidelines to individual families. They are intended to serve as a resource for health care providers to identify individuals who may benefit from cancer risk assessment and genetic counseling, to provide genetic professionals with an updated

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NCCN Guidelines® Insights: Biliary Tract Cancers, Version 2.2023

Featured Updates to the NCCN Guidelines

Al B. Benson III, Michael I. D’Angelica, Thomas Abrams, Daniel E. Abbott, Aijaz Ahmed, Daniel A. Anaya, Robert Anders, Chandrakanth Are, Melinda Bachini, David Binder, Mitesh Borad, Christopher Bowlus, Daniel Brown, Adam Burgoyne, Jason Castellanos, Prabhleen Chahal, Jordan Cloyd, Anne M. Covey, Evan S. Glazer, William G. Hawkins, Renuka Iyer, Rojymon Jacob, Lawrence Jennings, R. Kate Kelley, Robin Kim, Matthew Levine, Manisha Palta, James O. Park, Steven Raman, Sanjay Reddy, Sean Ronnekleiv-Kelly, Vaibhav Sahai, Gagandeep Singh, Stacey Stein, Anita Turk, Jean-Nicolas Vauthey, Alan P. Venook, Adam Yopp, Nicole McMillian, Ryan Schonfeld, and Cindy Hochstetler

germline testing, genetic counseling referral and potential germline testing should be considered in patients with BTCs with any of the following characteristics: young age at diagnosis, a strong personal or family history of cancer, no known risk factors

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Priority Rankings of Patient-Reported Outcomes for Pancreatic Ductal Adenocarcinoma: A Comparison of Patient and Physician Perspectives

Michelle Guan, Gillian Gresham, Arvind Shinde, Isaac Lapite, Jun Gong, Veronica R. Placencio-Hickok, Christopher B. Forrest, and Andrew E. Hendifar

performance status, and HRQoL in patients with advanced cancer with the incorporation of a rehabilitation program. 18 , 30 – 33 Routine multidisciplinary consultation with services such as supportive care, nutrition, genetic counseling, and social services

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Mode of Detection of Second Breast Cancers in Patients Undergoing Surveillance After Treatment of Ductal Carcinoma in Situ

Bethany T. Waites, Liisa Lyon, Gillian Kuehner, Patience Odele, Laurel A. Habel, and Raymond Liu

grade when developing a treatment plan, accessibility of genetic counseling, more accurate pathologic review, and an emphasis on margins at the time of surgical resection. The strengths of our study include the ability to follow a large cohort of DCIS

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Prospective Study of Fertility Preservation in Young Women With Breast Cancer in Mexico

Cynthia Villarreal-Garza, Fernanda Mesa-Chavez, Alejandra Plata de la Mora, Melina Miaja-Avila, Marisol Garcia-Garcia, Alan Fonseca, Sylvia de la Rosa-Pacheco, Marlid Cruz-Ramos, Manuel Rolando García Garza, Alejandro Mohar, and Enrique Bargallo-Rocha

cancer are invited to participate in J&F. The navigator discusses and provides educational material regarding relevant issues for YWBC, identifies patients’ needs, and assists in making early referrals to oncofertility, genetic counseling, and psycho

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Mammographic Breast Density: Effect on Imaging and Breast Cancer Risk

Renee W. Pinsky and Mark A. Helvie

as screening MRI and WB-US, and for genetic counseling and risk reduction efforts. EDITOR Kerrin M. Green, MA, Assistant Managing Editor, Journal of the National Comprehensive Cancer Network Disclosure: Kerrin M. Green, MA, has disclosed no relevant