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Exercise Programs for Cancer-Related Fatigue: Evidence and Clinical Guidelines

Margaret L. McNeely and Kerry S. Courneya

O ver the past decade, a significant increase has occurred in the amount and quality of research examining the role of exercise in managing cancer-related fatigue (CRF). 1 – 5 In fact, a recent systematic review noted that CRF is the most

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Psychostimulants for Cancer-Related Fatigue

William Breitbart and Yesne Alici

S everal pharmacologic agents have been considered and studied for the treatment of cancer-related fatigue, including psychostimulants, antidepressants, megestrol acetate, and amantadine. 1 A recent meta-analysis of pharmacologic treatment

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Studying Cancer-Related Fatigue: Report of the NCCN Scientific Research Committee

Joanne E. Mortimer, Andrea M. Barsevick, Charles L. Bennett, Ann M. Berger, Charles Cleeland, Shannon R. DeVader, Carmen Escalante, Jeffrey Gilreath, Arti Hurria, Tito R. Mendoza, and Hope S. Rugo

T he NCCN Cancer-Related Fatigue (CRF) Scientific Research Committee was convened in September 2009 to accomplish 3 objectives: 1) review the current methods to measure and interventions to treat CRF; 2) recommend a CRF measure or develop a new

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Cancer-Related Fatigue

Ann M. Berger, Amy Pickar Abernethy, Ashley Atkinson, Andrea M. Barsevick, William S. Breitbart, David Cella, Bernadine Cimprich, Charles Cleeland, Mario A. Eisenberger, Carmen P. Escalante, Paul B. Jacobsen, Phyllis Kaldor, Jennifer A. Ligibel, Barbara A. Murphy, Tracey O'Connor, William F. Pirl, Eve Rodler, Hope S. Rugo, Jay Thomas, and Lynne I. Wagner

Overview Fatigue is a common symptom in patients with cancer and is nearly universal in those undergoing cytotoxic chemotherapy, radiation therapy, bone marrow transplantation, or treatment with biologic response modifiers. 1 – 10 The symptom

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Cancer-Related Fatigue, Version 2.2015

Ann M. Berger, Kathi Mooney, Amy Alvarez-Perez, William S. Breitbart, Kristen M. Carpenter, David Cella, Charles Cleeland, Efrat Dotan, Mario A. Eisenberger, Carmen P. Escalante, Paul B. Jacobsen, Catherine Jankowski, Thomas LeBlanc, Jennifer A. Ligibel, Elizabeth Trice Loggers, Belinda Mandrell, Barbara A. Murphy, Oxana Palesh, William F. Pirl, Steven C. Plaxe, Michelle B. Riba, Hope S. Rugo, Carolina Salvador, Lynne I. Wagner, Nina D. Wagner-Johnston, Finly J. Zachariah, Mary Anne Bergman, and Courtney Smith

Fatigue is a common symptom in patients with cancer. It is nearly universal in those receiving cytotoxic chemotherapy, radiation therapy, bone marrow transplantation, or treatment with biologic response modifiers. 1 – 3 According to a survey of 1569

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A Cancer-Related Fatigue Clinic: Opportunities and Challenges

Carmen P. Escalante, Ellen Manzullo, and Rosalie Valdres

The authors receive grant funding from Ortho Biotech Oncology. References 1 Mock V Atkinson A Barsevick A NCCN cancer-related fatigue clinical practice guidelines in oncology . Oncology 2000 ; 14 : 151 – 161 . 2

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Fatigue is the Most Important Symptom for Advanced Cancer Patients Who Have Had Chemotherapy

Zeeshan Butt, Sarah K. Rosenbloom, Amy P. Abernethy, Jennifer L. Beaumont, Diane Paul, Debra Hampton, Paul B. Jacobsen, Karen L. Syrjala, Jamie H. Von Roenn, and David Cella

. The functional assessment of cancer therapy scale: development and validation of the general measure . J Clin Oncol 1993 ; 11 : 570 – 579 . 2. Winningham ML Nail LM Burke MB . Fatigue and the cancer experience: the state of the knowledge

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Update on Psychotropic Medications for Cancer-Related Fatigue

William Breitbart and Yesne Alici-Evcimen

. Curt GA Breitbart W Cella D . Impact of cancer-related fatigue on the lives of patients: new findings from the Fatigue Coalition . Oncologist 2000 ; 5 : 353 – 360 . 2. Hwang SS Chang VT Rue M Kasimis B . Multidimensional independent

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Modifying Cancer-Related Fatigue by Optimizing Sleep Quality

Ann Malone Berger and Sandra A. Mitchell

The authors have no financial interest, arrangement, or affiliation with the manufacturers of any products discussed in the article or their competitors. References 1. Prue G Rankin J Allen J . Cancer-related fatigue: a

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Combination Therapy of Physical Activity and Dexamethasone for Cancer-Related Fatigue: A Phase II Randomized Double-Blind Controlled Trial

Sriram Yennurajalingam, Vicente Valero, Zhanni Lu, Diane D. Liu, Naifa L. Busaidy, James M. Reuben, Carolina Diaz Fleming, Janet L. Williams, Kenneth R. Hess, Karen Basen-Engquist, and Eduardo Bruera

Background Cancer-related fatigue (CRF) in patients with advanced cancer is more frequent and severe than in those with early cancer or in cancer survivors. 1 In patients with advanced cancer, moderate to severe fatigue is associated with poor