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Breast Cancer Risk Reduction Clinical Practice Guidelines in Oncology

Breast cancer risk factor analysis allows the identification of women at very high risk for the future development of breast cancer. However, estimating risk for the individual woman is difficult, and most breast cancers are not attributable to risk factors other than female gender and increased age. These practice guidelines discuss known risk factors, strategies for reducing risk, and possible future developments.

For the most recent version of the guidelines, please visit NCCN.org

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Management of Toxicities of BTK Inhibitors in B-Cell Malignancies

Presented by: Muhammad Saad Hamid and Kirollos S. Hanna

bleeding in critical areas. Risk factors for bleeding include concurrent use of antiplatelet and anticoagulant drugs, with the strongest data linked to antiplatelet therapy. The use of warfarin, in particular, has been contraindicated with ibrutinib and

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VTE as a Quality Indicator

Myron Goldsmith, George Whitelaw, and Denise A. Cannaday

. Frequency, risk factors, and trends for venous thromboembolism among hospitalized cancer patients . Cancer 2007 ; 110 : 2339 – 2346 . 11. Wagman LD Baird MF Bennett CL . NCCN Clinical Practice Guidelines in Oncology: Venous Thromboembolic

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Current Concepts in Penile Cancer

Philippe E. Spiess, Simon Horenblas, Lance C. Pagliaro, Matthew C. Biagioli, Juanita Crook, Peter E. Clark, Richard E. Greenberg, and Cesar E. Ercole

/print certificate. Release date: May 13, 2013; Expiration date: May 13, 2014. Learning Objectives Upon completion of this activity, participants will be able to: Identify the risk factors associated with penile cancer. Discuss the rationale for

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Multiorgan Immune-Related Adverse Events During Treatment With Atezolizumab

Ganessan Kichenadasse, John O. Miners, Arduino A. Mangoni, Andrew Rowland, Ashley M. Hopkins, and Michael J. Sorich

patients with non–small cell lung cancer treated using atezolizumab monotherapy, we analyzed the incidence, severity, time course, treatment, outcomes, and risk factors of various organ-specific irAEs and their relationships with response rates

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New Persistent Opioid and Benzodiazepine Use After Curative-Intent Treatment in Patients With Breast Cancer

Mandy R. Sakamoto, Megan Eguchi, Christine M. Azelby, Jennifer R. Diamond, Christine M. Fisher, Virginia F. Borges, Cathy J. Bradley, and Peter Kabos

treatment remains high. We performed a retrospective cohort analysis using population-based data to evaluate new and persistent opioid and benzodiazepine use and risk factors among patients with breast cancer who received curative-intent treatment. Methods

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Hepatic Epithelioid Hemangioendothelioma in a Patient With Hemochromatosis

Nisar Ahmad, Denise M. Adams, Jiang Wang, Rajan Prakash, and Nagla Abdel Karim

,000. 3 It is slightly more common in women, with a female-to-male ratio of approximately 1.6:1.0. Risk factors for HEHE are not well-known. An association of HEHE with oral contraceptives has been suggested but not completely established. 4 , 5 HEHE

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Impact of Nonadherence to NCCN Adjuvant Radiotherapy Initiation Guidelines in Head and Neck Squamous Cell Carcinoma in an Underserved Urban Population

Anusha Ponduri, David Z. Liao, Nicolas F. Schlecht, Gregory Rosenblatt, Michael B. Prystowsky, Rafi Kabarriti, Madhur Garg, Thomas J. Ow, Bradley A. Schiff, Richard V. Smith, and Vikas Mehta

intervene in a prospective fashion. In this study, we sought to measure the impact of nonadherence to NCCN Guidelines on survival and disease recurrence in patients with HNSCC at a large urban health center, and investigated risk factors predictive of delay

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Efficacy and Toxicity Analysis of Capecitabine and Temozolomide in Neuroendocrine Neoplasms

Taymeyah Al-Toubah, Eleonora Pelle, Tiffany Valone, Mintallah Haider, and Jonathan R. Strosberg

gastrointestinal NETs. Although moderately powered studies are sufficient to determine critical outcomes such as ORR and PFS, larger databases are key to answering other important questions. These include the frequency of rare toxicities, risk factors for

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Complications of Multiple Myeloma Therapy, Part 1: Risk Reduction and Management of Peripheral Neuropathy and Asthenia

Paul G. Richardson, Jacob P. Laubach, Robert L. Schlossman, Constantine Mitsiades, and Kenneth Anderson

neuropathy may be detected in 11% to 52% and 39% to 46% of these populations, respectively. 1 – 6 Risk factors for PN include treatment-specific characteristics, such as therapy duration, dose intensity, and cumulative dose, and patient-specific factors