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Therese B. Bevers, Mark Helvie, Ermelinda Bonaccio, Kristine E. Calhoun, Mary B. Daly, William B. Farrar, Judy E. Garber, Richard Gray, Caprice C. Greenberg, Rachel Greenup, Nora M. Hansen, Randall E. Harris, Alexandra S. Heerdt, Teresa Helsten, Linda Hodgkiss, Tamarya L. Hoyt, John G. Huff, Lisa Jacobs, Constance Dobbins Lehman, Barbara Monsees, Bethany L. Niell, Catherine C. Parker, Mark Pearlman, Liane Philpotts, Laura B. Shepardson, Mary Lou Smith, Matthew Stein, Lusine Tumyan, Cheryl Williams, Mary Anne Bergman, and Rashmi Kumar

-producing lesions, potential phyllodes tumor, papillary lesions, radial scars, or other histologies of concern to the pathologist. 24 , 29 , 35 , 36 Support for this recommendation includes results of studies showing an underestimation of cancer when atypical

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NCCN Guidelines Insights: Kidney Cancer, Version 2.2020

Featured Updates to the NCCN Guidelines

Robert J. Motzer, Eric Jonasch, M. Dror Michaelson, Lakshminarayanan Nandagopal, John L. Gore, Saby George, Ajjai Alva, Naomi Haas, Michael R. Harrison, Elizabeth R. Plimack, Jeffrey Sosman, Neeraj Agarwal, Sam Bhayani, Toni K. Choueiri, Brian A. Costello, Ithaar H. Derweesh, Thomas H. Gallagher, Steven L. Hancock, Christos Kyriakopoulos, Chad LaGrange, Elaine T. Lam, Clayton Lau, Bryan Lewis, Brandon Manley, Brittany McCreery, Andrew McDonald, Amir Mortazavi, Phillip M. Pierorazio, Lee Ponsky, Bruce G. Redman, Bradley Somer, Geoffrey Wile, Mary A. Dwyer, CGC, Lydia J. Hammond, and Griselda Zuccarino-Catania

, multicenter study . J Clin Oncol 2009 ; 27 : 5794 – 5799 . 19826129 10.1200/JCO.2008.21.4809 17. Ficarra V , Schips L , Guillè F , . Multiinstitutional European validation of the 2002 TNM staging system in conventional and papillary localized

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John P. Sherbeck, Lili Zhao, and Richard W. Lieberman

. Int J Gynecol Cancer 2015 ; 25 : 1437 – 1444 . 5. Alagkiozidis I Weedon J Grossman A . Extent of lymph node dissection and overall survival in patients with uterine carcinosarcoma, papillary serous and endometrioid adenocarcinoma: a

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Aatur D. Singhi, Siraj M. Ali, Jill Lacy, Andrew Hendifar, Khanh Nguyen, Jamie Koo, Jon H. Chung, Joel Greenbowe, Jeffrey S. Ross, Marina N. Nikiforova, Herbert J. Zeh, Inderpal S. Sarkaria, Anil Dasyam, and Nathan Bahary

. ALK fusion genes, including EML4-ALK and STRN-ALK , have been identified in multiple cancer types, including lung adenocarcinoma, colorectal adenocarcinoma, breast cancer, renal cell carcinoma, renal medullary carcinoma, and papillary thyroid

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Ronan J. Kelly

. Several subtypes of thymic carcinoma exist, including squamous cell, basaloid, sarcomatoid, mucoepidermoid, papillary, lymphoepithelioma-like, and undifferentiated carcinomas. Knowledge of the tumor biology underlying the different phenotypes between

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Mary B. Daly, Robert Pilarski, Jennifer E. Axilbund, Michael Berry, Saundra S. Buys, Beth Crawford, Meagan Farmer, Susan Friedman, Judy E. Garber, Seema Khan, Catherine Klein, Wendy Kohlmann, Allison Kurian, Jennifer K. Litton, Lisa Madlensky, P. Kelly Marcom, Sofia D. Merajver, Kenneth Offit, Tuya Pal, Huma Rana, Gwen Reiser, Mark E. Robson, Kristen Mahoney Shannon, Elizabeth Swisher, Nicoleta C. Voian, Jeffrey N. Weitzel, Alison Whelan, Myra J. Wick, Georgia L. Wiesner, Mary Dwyer, Rashmi Kumar, and Susan Darlow

tumours in Norway: a nested case-control study . Br J Cancer 2004 ; 91 : 1829 – 1834 . 12. Jazaeri AA Lu K Schmandt R . Molecular determinants of tumor differentiation in papillary serous ovarian carcinoma . Mol Carcinog 2003 ; 36 : 53

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Philippe E. Spiess, Simon Horenblas, Lance C. Pagliaro, Matthew C. Biagioli, Juanita Crook, Peter E. Clark, Richard E. Greenberg, and Cesar E. Ercole

staging system in 2010, and recognizes 4 subtypes of SCC: verrucous, papillary squamous, warty, and basaloid (“see Staging Table, in the NCCN Clinical Practice Guidelines in Oncology for Penile Cancer, available online at NCCN.org [ST-1]”). Adenosquamous

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Benjamin R. Roman, Snehal G. Patel, Marilene B. Wang, Anna M. Pou, F. Christopher Holsinger, David Myssiorek, David Goldenberg, Samuel Swisher-McClure, Alexander Lin, Jatin P. Shah, and Judy A. Shea

variation in surveillance strategies after curative-intent surgery for upper aerodigestive tract cancer . Ann Surg Oncol 2006 ; 13 : 1063 – 1071 . 54. Wu AW Wang MB Nguyen CT . Surgical practice patterns in the treatment of papillary thyroid

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Yue Chen, Zi-Qi Zheng, Fo-Ping Chen, Jian-Ye Yan, Xiao-Dan Huang, Feng Li, Ying Sun, and Guan-Qun Zhou

28628563 11. Suh YJ , Kwon H , Kim SJ , . Factors affecting the locoregional recurrence of conventional papillary thyroid carcinoma after surgery: a retrospective analysis of 3381 patients . Ann Surg Oncol 2015 ; 22 : 3543 – 3549 . 25743326 10

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Robert J. Morgan Jr, Ronald D. Alvarez, Deborah K. Armstrong, Robert A. Burger, Lee-may Chen, Larry Copeland, Marta Ann Crispens, David M. Gershenson, Heidi J. Gray, Ardeshir Hakam, Laura J. Havrilesky, Carolyn Johnston, Shashikant Lele, Lainie Martin, Ursula A. Matulonis, David M. O’Malley, Richard T. Penson, Matthew A. Powell, Steven W. Remmenga, Paul Sabbatini, Joseph T. Santoso, Julian C. Schink, Nelson Teng, Theresa L. Werner, Mary A. Dwyer, and Miranda Hughes

, although MMMT has not been included in IP chemotherapy trials. 21 , 38 However, MMMT/carcinosarcoma is basically papillary serous carcinoma (ie, a poorly differentiated carcinoma); therefore, IP may be used for MMMT. NCCN Guidelines Insights