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EPR22-104: A Comparison of the Burden of Leukemia Amongst Various Regions of the World, 1990-2019

Alaaeldin Ahmed, Chinmay Jani, Padmanabh Bhatt, Harpreet Singh, Ruchi Jani, Joseph Shalhoub, Dominic Marshall, Prudence Lam, and Justin Salciccioli

Background : Acute Myeloid Leukemia (AML) is the most common acute leukemia in adults accounting for about 80% of adult leukemia cases. In contrast, it accounts for less than 10% of children less than ten years of age. In the last two decades

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HSR24-159: Relationship Between Durable Transfusion Independence (TI) and Survival Outcomes in Patients (Pts) With Lower-Risk Myelodysplastic Syndrome (LR-MDS): An Analysis From US Health Insurance Claims Data

Rami S. Komrokji, Nishan Sengupta, Dylan Supina, Shyamala Navada, Ravi Potluri, Rohit Tyagi, Timothy Werwath, Zhouer Xie, Eric Padron, and David Sallman

.1, D46.9, D46.A, and D46.B) from Oct 2015 to Mar 2023. No diagnosis of MDS/acute myeloid leukemia (AML) or use of higher-risk MDS or AML medication before their respective index diagnosis dates were allowed. Lines of treatment were determined by the

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CLO23-066: Risk of Secondary Malignancies After Platinum-Based Chemotherapy in Testicular Seminoma Patients: A Population-Based Study

Hiffsa Taj, Ayman Qasrawi, and Zin Myint

myeloid leukemia (SIR 11.86, CI: 5.12–23.38). Conclusions: In our study, patients with seminoma had increased risk of contralateral testis cancers. Patients with stage I who received chemotherapy did not have increased risk of other solid or hematologic

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QIM23-131: A Retrospective Review of Myelodysplastic Syndrome Management (MDS) at Watson Clinic LLP: From Diagnosis to Primary Course of Treatment

Shane Burke, Galina Vugman, Noreen McGowan, and Michelle Sharrett

Comprehensive Cancer Network (NCCN) Guidelines recommend treatment patterns based on risk of progression into Acute Myeloid Leukemia (AML). Adherence to these guidelines improves survival rates in patients with MDS. An MDS work-up should include an extensive

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Developmental Therapeutics for Myelodysplastic Syndromes

Aung Naing, Lubomir Sokol, and Alan F. List

. 22. Foran J Paquette R Copper M . A phase I study of repeated oral dosing with SU11248 for the treatment of patients with acute myeloid leukemia who have failed or are not eligible for conventional chemotherapy [abstract] . Blood 2002 ; 100

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Epigenetic Modulation in Hematologic Malignancies: Challenges and Progress

Constantine S. Mitsiades and Kenneth C. Anderson

-sensitive ovarian tumors . Nat Med 2003 ; 9 : 568 - 574 . 54. Melki JR Vincent PC Clark SJ . Concurrent DNA hypermethylation of multiple genes in acute myeloid leukemia . Cancer Res 1999 ; 59 : 3730 - 3740 . 55. Hegi ME Liu L Herman JG

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Improving Outcomes of Acute Promyelocytic Leukemia in the Current Era: Analysis of the SEER Database

Guru Subramanian Guru Murthy, Aniko Szabo, Laura Michaelis, Karen-Sue Carlson, Lyndsey Runaas, Sameem Abedin, and Ehab Atallah

Background Acute promyelocytic leukemia (APL) is a unique subtype of acute myeloid leukemia (AML) that is characterized by chromosomal translocation t(15;17) with fusion of PML-RARA genes and cell-cycle arrest at the promyelocyte stage. 1 APL

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Treatment Disparities Faced by Undocumented Workers From Low- and Middle-Income Countries in the United States With Hematologic Malignancies

Sara E. Nunnery, Andrew E. Fintel, W. Clay Jackson, Jason C. Chandler, Michael O. Ugwueke, and Mike G. Martin

urgent leukapheresis, a bone marrow biopsy was performed and a diagnosis of acute myeloid leukemia (AML) was made. He was started on induction chemotherapy with cytarabine, idarubicin, and cladribine (7+3+5). 4 The final bone marrow biopsy revealed high

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Infectious Complications Associated With Immunomodulating Monoclonal Antibodies Used in the Treatment of Hematologic Malignancy

Sophia Koo and Lindsey R. Baden

lymphoproliferative disorders . Blood 2002 ; 100 : 3121 – 3127 . 51. Ho AY Pagliuca A Kenyon M . Reduced-intensity allogeneic hematopoietic stem cell transplantation for myelodysplastic syndrome and acute myeloid leukemia with multilineage dysplasia

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The NCCN 2019 Annual Congress: Hematologic Malignancies

Robert W. Carlson

neoplasms. Also in the congress, blood cancer experts described updates in treatment strategies for Hodgkin lymphoma, advances in first-line acute myeloid leukemia management, and progress in personalized therapeutic approaches in myelodysplastic syndromes