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Kimberly Davies, Matthew Barth, Saro Armenian, Anthony N. Audino, Phillip Barnette, Branko Cuglievan, Hilda Ding, James B. Ford, Paul J. Galardy, Rebecca Gardner, Rabi Hanna, Robert Hayashi, Alexandra E. Kovach, Andrea Judit Machnitz, Kelly W. Maloney, Lianna Marks, Kristin Page, Anne F. Reilly, Joanna L. Weinstein, Ana C. Xavier, Nicole R. McMillian, and Deborah A. Freedman-Cass

diagnosis, staging, initial treatment, disease reassessment, surveillance, therapy for relapsed/refractory disease, and supportive care for clinicians who treat sporadic pediatric BL and DLBCL. These guidelines do not include recommendations for the

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Erich M. Sturgis and K. Kian Ang

limited nodal stage: N0, N1, and N2a). Contemporary studies have found very limited stratification of HPV-associated oropharyngeal cancer outcomes attributable to the TNM staging system, partly because very few HPV-positive cancers present without

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Donald A. Podoloff, Ranjana H. Advani, Craig Allred, Al B. Benson III, Elizabeth Brown, Harold J. Burstein, Robert W. Carlson, R. Edward Coleman, Myron S. Czuczman, Dominique Delbeke, Stephen B. Edge, David S. Ettinger, Frederic W. Grannis Jr., Bruce E. Hillner, John M. Hoffman, Krystyna Kiel, Ritsuko Komaki, Steven M. Larson, David A. Mankoff, Kenneth E. Rosenzweig, John M. Skibber, Joachim Yahalom, JQ Michael Yu, and Andrew D. Zelenetz

The use of positron emission tomography (PET scanning) is increasing rapidly in the United States. The most common use of PET scanning is related to oncology, especially in staging and managing lymphoma, lung cancer, and colorectal cancer ( Figure 1

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Thomas W. Flaig

for primary treatment of stage II disease in cystectomy candidates. For patients ineligible for cystectomy, the recommended primary treatment is concurrent CRT or radiotherapy. Staging Changes In 2017, AJCC incorporated changes in staging criteria for

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B. Daniel Campos and Jean F. Botha

Edited by Kerrin G. Robinson

hepatocellular carcinoma: the Milan criteria and beyond . Liver Transpl 2006 ; 12 ( 11 Suppl 2 ): S8 – 13 25 Yao FY Kerlan RK Jr Hirose R . Excellent outcome following down-staging of hepatocellular carcinoma prior to liver transplantation: an

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Brian Vicuna and Al B. Benson III

. Ann Surg 1954 ; 139 : 846 – 852 . 6. Compton CC . Key issues in reporting common cancer specimens: problems in pathologic staging of colon cancer . Arch Pathol Lab Med 2006 ; 130 : 318 – 324 . 7. O'Connell JB Maggard MA Ko

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Arif Kamal, Tian Zhang, Steve Power, and P. Kelly Marcom

services in early-stage breast cancer (ESBC), stating, “Don't perform PET, CT, and radionuclide bone scans in the staging of early breast cancer at low risk for metastasis.” 1 For these recommendations, the Choosing Wisely initiative defines early

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Darren Sigal, Marie Tartar, Marin Xavier, Fei Bao, Patrick Foley, David Luo, Jason Christiansen, Zachary Hornby, Edna Chow Maneval, and Pratik Multani

incidence over the past 30 years, making effective NET therapy an important unmet medical need. 2 Contemporary understanding of NETs has been clouded by divergent nomenclature, staging, and grading systems. NETs can form anywhere within the diffuse

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Wui-Jin Koh, Nadeem R. Abu-Rustum, Sarah Bean, Kristin Bradley, Susana M. Campos, Kathleen R. Cho, Hye Sook Chon, Christina Chu, Rachel Clark, David Cohn, Marta Ann Crispens, Shari Damast, Oliver Dorigo, Patricia J. Eifel, Christine M. Fisher, Peter Frederick, David K. Gaffney, Ernest Han, Warner K. Huh, John R. Lurain III, Andrea Mariani, David Mutch, Christa Nagel, Larissa Nekhlyudov, Amanda Nickles Fader, Steven W. Remmenga, R. Kevin Reynolds, Todd Tillmanns, Stefanie Ueda, Emily Wyse, Catheryn M. Yashar, Nicole R. McMillian, and Jillian L. Scavone

histologic types are not within the scope of these guidelines. Currently, the International Federation of Gynecology and Obstetrics (FIGO) evaluation procedures for staging are limited to colposcopy, biopsy, conization of the cervix, cystoscopy, and

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Derek J. Erstad, Mariela Blum, Jeannelyn S. Estrella, Prajnan Das, Bruce D. Minsky, Jaffer A. Ajani, Paul F. Mansfield, Naruhiko Ikoma, and Brian D. Badgwell

appropriately requires a lower ELN count and LNR for discrimination, whereas the converse is true for high-burden disease. Given the inaccuracy of clinical staging in gastric cancer, it is prudent to apply to all patients a more stringent threshold predicated on