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Advances in Supportive Care for Multiple Myeloma

Noopur S. Raje, Andrew J. Yee, and G. David Roodman

3.7 years. 35 Dental extractions are a major risk factor for the development of ONJ. 34 , 36 Attention to dental hygiene and minimizing invasive procedures (eg, tooth extractions, dental implants) may reduce the risk of ONJ. 37 IMWG guidelines

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Managing Pain in Patients and Survivors: Challenges Within the United States Opioid Crisis

Judith A. Paice

. “For goal-setting surrounding pain, the focus has shifted from looking for zero on a pain scale to improving patients’ function. For a thorough assessment, we need to ask patients about risk factors for misuse. Family history is a crude proxy for risk

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Mammographic Breast Density: Effect on Imaging and Breast Cancer Risk

Renee W. Pinsky and Mark A. Helvie

area of tissue is known as percent mammographic density ( PMD ). Breast Density Measurement Recognition of breast density as a breast cancer risk factor and measurement of density have been evolving for more than 30 years. This affects a large number

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Multidisciplinary Management of Locally Advanced Rectal Cancer: Neoadjuvant Approaches

Swaminathan Murugappan, William P. Harris, Christopher G. Willett, and Edward Lin

cancer, requiring specific multimodality approaches. This article reviews the biology, risk factors, and evolving treatment of LARC. Important advances have been made in the past 3 decades in the multimodality treatment of patients with LARC. In the

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Myelodysplastic Syndromes, Version 2.2015

Peter L. Greenberg, Richard M. Stone, Rafael Bejar, John M. Bennett, Clara D. Bloomfield, Uma Borate, Carlos M. De Castro, H. Joachim Deeg, Amy E. DeZern, Amir T. Fathi, Olga Frankfurt, Karin Gaensler, Guillermo Garcia-Manero, Elizabeth A. Griffiths, David Head, Virginia Klimek, Rami Komrokji, Lisa A. Kujawski, Lori J. Maness, Margaret R. O’Donnell, Daniel A. Pollyea, Bart Scott, Paul J. Shami, Brady L. Stein, Peter Westervelt, Benton Wheeler, Dorothy A. Shead, and Courtney Smith

DNMT3A, U2AF1, SRSF2, CBL, PRPF8, SETBP1 , and KRAS . 23 , 26 , 29 – 32 Mutations of SF3B1 have been associated with a more favorable prognosis, but this may not be an independent risk factor. 26 , 33 Mutations of TP53 are strongly associated

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Role of Laparoscopic Surgery in the Management of Endometrial Cancer

Meaghan Tenney and Joan L. Walker

RJ . Relationship between surgical-pathological risk factors and outcome in clinical stage I and II carcinoma of the endometrium: a Gynecologic Oncology Group study . Gynecol Oncol 1991 ; 40 : 55 – 65 . 5 FIGO . Corpus cancer staging

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Opioid Misuse and Abuse: Risk Assessment and Management in Patients with Cancer Pain

Doralina L. Anghelescu, Jennifer Harman Ehrentraut, and Lane G. Faughnan

Treatment of chronic pain with opioids is associated with the risk of abuse, misuse, diversion, and addiction. 1 Patients receiving chronic opioid therapy (COT) for malignant or nonmalignant pain should be assessed for risk factors of abuse and

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Lung Cancer Screening, Version 3.2018, NCCN Clinical Practice Guidelines in Oncology

Douglas E. Wood, Ella A. Kazerooni, Scott L. Baum, George A. Eapen, David S. Ettinger, Lifang Hou, David M. Jackman, Donald Klippenstein, Rohit Kumar, Rudy P. Lackner, Lorriana E. Leard, Inga T. Lennes, Ann N.C. Leung, Samir S. Makani, Pierre P. Massion, Peter Mazzone, Robert E. Merritt, Bryan F. Meyers, David E. Midthun, Sudhakar Pipavath, Christie Pratt, Chakravarthy Reddy, Mary E. Reid, Arnold J. Rotter, Peter B. Sachs, Matthew B. Schabath, Mark L. Schiebler, Betty C. Tong, William D. Travis, Benjamin Wei, Stephen C. Yang, Kristina M. Gregory, and Miranda Hughes

The NCCN Guidelines 1) describe risk factors for lung cancer; 2) recommend criteria for selecting individuals with high-risk factors for screening; 3) provide recommendations for evaluation and follow-up of lung nodules found during screening; 4

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BPI19-015: Reduction of Inappropriate Prophylactic Pegylated Granulocyte Colony-Stimulating Factor (pGCSF) Use for Lung Cancer Patients: Five-Year Follow Up of a Quality Improvement (QI) Initiative at the Cleveland Clinic Taussig Cancer Institute (TCI)

Anne K. Hubben, Nathan Pennell, Marc Shapiro, Craig Savage, and James P. Stevenson

chemotherapy initiated between January 2016 and August 2018. PP pGCSF use was appropriate if prescribed with chemotherapy regimens with a high risk (>20%) for FN, or intermediate risk (10%–20%) if other accepted FN risk factors were present. PP use with FN low

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Evidence and Controversies in the Use of Post-Mastectomy Radiation

Shaneli A. Fernando and Stephen B. Edge

with or without tamoxifen and without radiotherapy: results from five National Surgical Adjuvant Breast and Bowel Project randomized clinical trials . J Clin Oncol 2004 ; 22 : 4247 – 4254 . 7. Wallgren A Bonetti M Gelber RD . Risk factors