in Oncology (NCCN Guidelines) for NSCLC, many chemotherapy drugs are useful for treating patients with advanced-stage NSCLC. Among them are platinum agents (eg, cisplatin, carboplatin), taxanes (eg, paclitaxel, albumin-bound paclitaxel, docetaxel
Search Results
Advances in the Treatment of Non-Small Cell Lung Cancer
Leora Horn
Induction Chemotherapy for Head and Neck Cancer: Will History Repeat Itself?
Athanassios Argiris
-fluoruracil (F) versus P, F and paclitaxel (T) as induction therapy in locally advanced head & neck cancer (LAHNC) (Abstr) . Proc Am Soc Clin Oncol 2003 ; 22 : A1997 . 8 Vermorken JB Remenar E Van Herpen C . Standard cisplatin/infusional 5
Cervical Cancer, Version 2.2015
Wui-Jin Koh, Benjamin E. Greer, Nadeem R. Abu-Rustum, Sachin M. Apte, Susana M. Campos, Kathleen R. Cho, Christina Chu, David Cohn, Marta Ann Crispens, Oliver Dorigo, Patricia J. Eifel, Christine M. Fisher, Peter Frederick, David K. Gaffney, Ernest Han, Warner K. Huh, John R. Lurain III, David Mutch, Amanda Nickles Fader, Steven W. Remmenga, R. Kevin Reynolds, Nelson Teng, Todd Tillmanns, Fidel A. Valea, Catheryn M. Yashar, Nicole R. McMillian, and Jillian L. Scavone
single agents in the metastatic disease setting based on several randomized phase III trials. 18 , 19 Cisplatin is a standard backbone of combination chemotherapy regimens, and cisplatin-based chemotherapy regimens (eg, cisplatin/paclitaxel
Point: Intraperitoneal Chemotherapy in the Management of Ovarian Cancer
Maurie Markman
: 4265 – 4269 . 16 Francis P Rowinsky E Schneider J . Phase 1 feasibility and pharmacologic study of weekly intraperitoneal paclitaxel: A Gynecologic Oncology Group pilot study . J Clin Oncol 1995 ; 13 : 2961 – 2967 . 17 Markman
Chemotherapy Hypersensitivity Reactions in Ovarian Cancer
Matthieu Picard, Ursula A. Matulonis, and Mariana Castells
doxorubicin (PLD) seems to significantly reduce the incidence of HSRs attributable to carboplatin compared with administering carboplatin as a single agent or in combination with paclitaxel. 31 , 32 The effect of PLD on reducing carboplatin-related infusion
Novel Agents for Metastatic Triple-Negative Breast Cancer: Finding the Positive in the Negative
Neelima Vidula, Leif W. Ellisen, and Aditya Bardia
III study compared veliparib with carboplatin and paclitaxel followed by maintenance veliparib versus chemotherapy in germline BRCA1/2 -mutant HER2-negative advanced breast cancer. 18 Median PFS improved from 12.6 to 14.5 months with the addition of
Updates in HER2-Positive and Triple-Negative Breast Cancers
Presented by: Melinda L. Telli and William J. Gradishar
1mic disease. 3 Treatment with weekly paclitaxel for 12 cycles plus trastuzumab for 1 year led to a 7-year OS rate of 95%, with only 4 of 406 patients experiencing distant recurrences. The subsequent ATEMPT trial evaluated the newer agent ado
PACIFIC: An Ocean of Hope in Patients With Stage III Unresectable Non–Small Cell Lung Cancer
Dipesh Uprety and David E. Marinier
used for concurrent CRT, including cisplatin/etoposide, carboplatin/paclitaxel, cisplatin/vinblastine, and, for nonsquamous pathology, carboplatin or cisplatin with pemetrexed. 7 The carboplatin/paclitaxel regimen is given weekly with radiation therapy
CRE24-050: Microangiopathic Hemolytic Anemia as the Presenting Manifestation of Metastatic Breast Cancer
Nirmala Ghimirey, Phuong Uyen Vo, James Dibb, Jordan Hatch, and Sameer Mahesh
carcinoma: ER+/PR-/HER2-. The patient’s most recent mammography was two months prior to presentation and did not show evidence of malignancy, even in retrospective analysis. With the diagnosis of metastatic breast cancer, she was started on paclitaxel. After
HSR21-060: Real-World Treatment Patterns After Trastuzumab-Based Regimen in Patients With HER2-Positive Metastatic Gastric Cancer in the United States
Feng Lin, Jinlin Song, Melissa Pavilack, Jipan Xie, Catherine Fernan, Ahmed Noman, and Winghan Jacqueline Kwong
patients who used TBR as 1L, 130 initiated 2L treatment and trastuzumab was used again as 2L in 72 patients. The most common regimens used in 2L post 1L TBR were paclitaxel + ramucirumab (15.4%), FOLFOX + trastuzumab (11.5%), and capecitabine + trastuzumab