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standards. 22 VTR data were obtained via chart review by trained abstractors and included data associated with health service use and clinical, treatment, and tumor characteristics. The VDW pharmacy files provided data on national drug code

enrollment. Results Cohort Selection and Characteristics Of 27,456,015 women enrolled from 2004 to 2016, we identified 141,672 aged 40 to 64 years with evidence of a personal breast cancer history meeting our inclusion/exclusion criteria

original ALTTO trial. 10 Statistical Considerations Patient baseline characteristics were compared with respect to BMI category (underweight, normal weight, overweight, obese) using the chi-square test. Weight change was calculated as a percentage (by

for categorical variables. Association Between Clinical Characteristics and Upstaging Frequencies Associations between clinical characteristics and upstaging frequencies were assessed using the Fisher exact test for categorical variables and the

frequency and percentages where appropriate. The Student t test was used to compare baseline characteristics, frailty scores, and chemoimmunotherapy cycles received between frail and nonfrail patients. The chi-square test was used to compare categorical

. Clinical data included age at diagnosis, race, diagnosis year, family history of breast cancer, and breast cancer–specific genetic mutation status. Tumor characteristic data included AJCC stage, grade, size, and estrogen receptor (ER), progesterone receptor

potential associations between sociodemographic, stage, estrogen receptor (ER)/progesterone receptor (PR) status, and tumor and treatment characteristics using Pearson chi-square or Fisher exact tests. Survival analysis using Kaplan-Meier curves Figure 1

years. 4 , 5 Covariates Patient demographic and clinical characteristics were compared and used for model adjustment, including age at index diagnosis, race (white, black, other) type of MBC (de novo vs treated, secondary metastatic disease), HR status

delivery of postoperative chemotherapy include clinical factors, such as patient age, extent of postoperative complications, and presence of lymph node metastases. 10 – 13 In contrast, sociodemographic characteristics influencing receipt of adjuvant

cancer and a short life expectancy in the United States. Subjects/Patients and Methods Patient Characteristics and Study Design A population-based study was conducted of patients with low-risk prostate cancer identified by the SEER