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Michelle C. Nguyen, Manisha H. Shah, David A. Liebner, Floor J. Backes, John Phay, and Lawrence A. Shirley

–small cell lung cancer, classical Hodgkin lymphoma, gastric cancer, head and neck squamous cell cancer, urothelial bladder cancer, and microsatellite-unstable tumors. Multiple clinical trials are currently underway to evaluate its effectiveness in other solid

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Robert J. Motzer, Eric Jonasch, Neeraj Agarwal, Clair Beard, Sam Bhayani, Graeme B. Bolger, Sam S. Chang, Toni K. Choueiri, Ithaar H. Derweesh, Shilpa Gupta, Steven L. Hancock, Jenny J. Kim, Timothy M. Kuzel, Elaine T. Lam, Clayton Lau, Ellis G. Levine, Daniel W. Lin, Kim A. Margolin, M. Dror Michaelson, Thomas Olencki, Roberto Pili, Elizabeth R. Plimack, Edward N. Rampersaud, Bruce G. Redman, Charles J. Ryan, Joel Sheinfeld, Kanishka Sircar, Brad Somer, Jue Wang, Richard B. Wilder, Mary A. Dwyer, and Rashmi Kumar

- 50 Chemotherapy regimens used in the treatment of bladder cancer have been reported to achieve responses in collecting duct carcinoma. In a multicenter prospective study, 23 patients with no prior therapy were treated with a combination of

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Lainie Martin and Russell J. Schilder

Kraemer K . Vascular endothelial growth factor antisense pretreatment of bladder cancer cells significantly enhances the cytotoxicity of mitomycin C, gemcitabine and cisplatin . J Urol 2005 ; 174 : 328 – 331 . 12. Sanborn RE Sandler AB

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Al B. Benson III, Michael I. D’Angelica, Thomas A. Abrams, Chandrakanth Are, P. Mark Bloomston, Daniel T. Chang, Bryan M. Clary, Anne M. Covey, William D. Ensminger, Renuka Iyer, R. Kate Kelley, David Linehan, Mokenge P. Malafa, Steven G. Meranze, James O. Park, Timothy Pawlik, James A. Posey, Courtney Scaife, Tracey Schefter, Elin R. Sigurdson, G. Gary Tian, Jean-Nicolas Vauthey, Alan P. Venook, Yun Yen, Andrew X. Zhu, Karin G. Hoffmann, Nicole R. McMillian, and Hema Sundar

: 893 – 901 . 34. Agarwal AK Kalayarasan R Javed A . Role of staging laparoscopy in primary gall bladder cancer—an analysis of 409 patients: a prospective study to evaluate the role of staging laparoscopy in the management of gallbladder

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Suneel D. Kamath, Sheetal M. Kircher, and Al B. Benson III

distribution compared with cancer burden showed that breast, prostate, and brain cancers and leukemia were well funded, whereas colorectal, pancreatic, liver and bile duct, endometrial, and bladder cancers were poorly funded. 17 Based on these data, it is

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Carlotta Palumbo, Francesco A. Mistretta, Sophie Knipper, Angela Pecoraro, Zhe Tian, Shahrokh F. Shariat, Fred Saad, Claudio Simeone, Alberto Briganti, Alessandro Antonelli, and Pierre I. Karakiewicz

after radical cystectomy for bladder cancer: evidence for a patient changing risk profile over time . Eur Urol 2014 ; 66 : 361 – 370 . 10.1016/j.eururo.2013.09.050 24139235 9. Henson DE , Ries LA , Carriaga MT . Conditional survival of 56

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Nikolaos A. Trikalinos, Amy Zhou, Maria B. Majella Doyle, Kathryn J. Fowler, Ashley Morton, Neeta Vachharajani, Manik Amin, Jesse W. Keller, William C. Chapman, Elizabeth M. Brunt, and Benjamin R. Tan

unresectable biliary cancer including gall bladder cancer: a Korean Cancer Study Group phase II trial . Cancer Chemother Pharmacol 2010 ; 65 : 641 – 647 . 24. Lubner SJ Mahoney MR Kolesar JL . Report of a multicenter phase II trial testing a

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Pablo Maroto, Georgia Anguera, Juan Maria Roldan-Romero, Maria Apellániz-Ruiz, Ferran Algaba, Jacqueline Boonman, Mark Nellist, Cristina Montero-Conde, Alberto Cascón, Mercedes Robledo, and Cristina Rodríguez-Antona

number of cases included was low, stressing the need for additional studies. Extraordinary responses to mTOR inhibitors have rarely been described in patients with cancer. These responses include a patient with metastatic bladder cancer who experienced

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Emil Lou, Donna D'Souza, and Andrew C. Nelson

1, 2016 . 17. Grimmond SM Raghavan D Russell PJ . Detection of a rare point mutation in Ki-ras of a human bladder cancer xenograft by polymerase chain reaction and direct sequencing . Urol Res 1992 ; 20 : 121 – 126 . 18

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Crystal S. Denlinger, Jennifer A. Ligibel, Madhuri Are, K. Scott Baker, Wendy Demark-Wahnefried, Don Dizon, Debra L. Friedman, Mindy Goldman, Lee Jones, Allison King, Grace H. Ku, Elizabeth Kvale, Terry S. Langbaum, Kristin Leonardi-Warren, Mary S. McCabe, Michelle Melisko, Jose G. Montoya, Kathi Mooney, Mary Ann Morgan, Javid J. Moslehi, Tracey O’Connor, Linda Overholser, Electra D. Paskett, Jeffrey Peppercorn, Muhammad Raza, M. Alma Rodriguez, Karen L. Syrjala, Susan G. Urba, Mark T. Wakabayashi, Phyllis Zee, Nicole R. McMillian, and Deborah A. Freedman-Cass

participating in NCCTG and NSABP adjuvant chemotherapy trials . J Clin Oncol 2012 ; 30 : 406 – 412 . 6. Wyszynski A Tanyos SA Rees JR . Body mass and smoking are modifiable risk factors for recurrent bladder cancer . Cancer 2014 ; 120 : 408