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Shane Burke, Galina Vugman, Noreen McGowan, and Michelle Sharrett

Comprehensive Cancer Network (NCCN) Guidelines recommend treatment patterns based on risk of progression into Acute Myeloid Leukemia (AML). Adherence to these guidelines improves survival rates in patients with MDS. An MDS work-up should include an extensive

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Alaaeldin Ahmed, Chinmay Jani, Padmanabh Bhatt, Harpreet Singh, Ruchi Jani, Joseph Shalhoub, Dominic Marshall, Prudence Lam, and Justin Salciccioli

Background : Acute Myeloid Leukemia (AML) is the most common acute leukemia in adults accounting for about 80% of adult leukemia cases. In contrast, it accounts for less than 10% of children less than ten years of age. In the last two decades

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Moon Ley Tung, Athena Puski, Jennifer L Stinson, Nicole Huser, and Madeline VanDerGraaf

Background: Hereditary myeloid malignancy syndromes (HMMS) are increasingly recognized in adult patients with myelodysplastic syndrome (MDS) or acute myeloid leukemia (AML). Timely diagnosis of HMMS is critical to ensure appropriate bone marrow

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Hiffsa Taj, Ayman Qasrawi, and Zin Myint

myeloid leukemia (SIR 11.86, CI: 5.12–23.38). Conclusions: In our study, patients with seminoma had increased risk of contralateral testis cancers. Patients with stage I who received chemotherapy did not have increased risk of other solid or hematologic

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CME/CE articles published in previous issues of JNCCN: Exocrine Pancreas Cancer and Thromboembolic Events: A Systematic Literature Review Expiration Date: 7/7/13 Monitoring Minimal Residual Disease in Acute Myeloid Leukemia: Ready

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/4/13 Exocrine Pancreas Cancer and Thromboembolic Events: A Systematic Literature Review Expiration Date: 7/7/13 Monitoring Minimal Residual Disease in Acute Myeloid Leukemia: Ready for Prime Time? Expiration Date: 8/7/13 Androgen Deprivation Therapy

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Constantine S. Mitsiades and Kenneth C. Anderson

-sensitive ovarian tumors . Nat Med 2003 ; 9 : 568 - 574 . 54. Melki JR Vincent PC Clark SJ . Concurrent DNA hypermethylation of multiple genes in acute myeloid leukemia . Cancer Res 1999 ; 59 : 3730 - 3740 . 55. Hegi ME Liu L Herman JG

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Aung Naing, Lubomir Sokol, and Alan F. List

. 22. Foran J Paquette R Copper M . A phase I study of repeated oral dosing with SU11248 for the treatment of patients with acute myeloid leukemia who have failed or are not eligible for conventional chemotherapy [abstract] . Blood 2002 ; 100

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Guru Subramanian Guru Murthy, Aniko Szabo, Laura Michaelis, Karen-Sue Carlson, Lyndsey Runaas, Sameem Abedin, and Ehab Atallah

Background Acute promyelocytic leukemia (APL) is a unique subtype of acute myeloid leukemia (AML) that is characterized by chromosomal translocation t(15;17) with fusion of PML-RARA genes and cell-cycle arrest at the promyelocyte stage. 1 APL

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Sara E. Nunnery, Andrew E. Fintel, W. Clay Jackson, Jason C. Chandler, Michael O. Ugwueke, and Mike G. Martin

urgent leukapheresis, a bone marrow biopsy was performed and a diagnosis of acute myeloid leukemia (AML) was made. He was started on induction chemotherapy with cytarabine, idarubicin, and cladribine (7+3+5). 4 The final bone marrow biopsy revealed high