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Updates to the Management of Patients With Relapsed or Refractory Indolent Follicular and Marginal Zone Lymphomas

Presented by: Ann S. LaCasce and Ariela Noy

Therapeutics announced the voluntary withdraw of umbralisib (UKONIQ) from sale for the approved indications of adult patients with MZL who have received at least one prior anti-CD20–based regimen and for adult patients with FL who have received at least 3 prior

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NCCN Guidelines Insights: Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma, Version 2.2019

William G. Wierda, John C. Byrd, Jeremy S. Abramson, Syed F. Bilgrami, Greg Bociek, Danielle Brander, Jennifer Brown, Asher A. Chanan-Khan, Julio C. Chavez, Steve E. Coutre, Randall S. Davis, Christopher D. Fletcher, Brian Hill, Brad S. Kahl, Manali Kamdar, Lawrence D. Kaplan, Nadia Khan, Thomas J. Kipps, Shuo Ma, Sami Malek, Anthony Mato, Claudio Mosse, Vishala T. Neppalli, Mazyar Shadman, Tanya Siddiqi, Deborah Stephens, Nina Wagner, Mary A. Dwyer, and Hema Sundar

/research support from AbbVie, Inc.; Acerta Pharma, LLC; Cyclacel Pharmaceuticals, Inc.; Gilead Sciences, Inc.; Intrexon Corporation; Juno Therapeutics, Inc.; Kite Pharma, Inc.; Oncternal Therapeutics; Precigen, Inc.; Xencor, Inc.; Pharmacyclics, Inc.; Roche

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Communicating Treatment Options to Older Patients: Challenges and Opportunities

Arti Hurria

of new therapeutics. Although oncology therapeutics undergo a stringent approval process under FDA regulations, older adults are inexplicably under-represented in registration trials. As of 1993, federal law has mandated that the NIH include and

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Systemic Management of Colorectal Cancer

Wells A. Messersmith

“You really can't treat colorectal cancer [CRC] today without molecular testing,” remarked Wells A. Messersmith, MD, Co-Director of the Developmental Therapeutics Program, University of Colorado Cancer Center, and Professor of Medicine, Director

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Active Systemic Treatment of Pancreatic Cancer

Margaret Tempero

Biotech Resources, LLC, NeoHealth Inc., Novocure, Opsona Therapeutics, Portola Pharmaceuticals, Inc., and Threshold Pharmaceuticals Inc.; and grant/research support from Celgene Corporation and Halozyme Therapeutics, Inc.; and she has served as a

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NCCN Guidelines: Pretransplant Recipient Evaluation and Management of Graft-Versus-Host Disease

Corey Cutler and Steven Z. Pavletic

clinical management have not changed, though they have become more complicated with the development and even FDA approval of new drugs for this indication. Similarly, use of HCT has shifted with the development of novel therapeutics in leukemia and lymphoma

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NCCN Guidelines Updates: Management of Metastatic Colorectal Cancer

Wells A. Messersmith

Guidelines regarding BRAF . Abbreviation: mAb, monoclonal antibody. Disclosures: Dr. Messersmith has disclosed that he receives institutional grant/research support from Alexo Therapeutics, Inc.; D3 Pharma; Genentech, Inc.; Immunomedics; Incyte; Millennium

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Primary Androgen Deprivation Therapy for Nonmetastatic Prostate Cancer in Asia: Unique or Not?

Masaki Shiota

expectancy <10 years was challenged. This study has several limitations. First, the data on diagnosis, therapeutics, and outcome are very limited, and Gleason score, prostate-specific antigen level at diagnosis, detailed clinical stage and modality used for

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Advances in the Care of Adult Patients With Acute Lymphoblastic Leukemia: Optimism Tempered by Reality

Joseph C. Alvarnas and Patrick A. Brown

new classes of antileukemia drugs and cellular therapeutics are fast becoming part of our ALL care strategy. These include therapeutics targeted at the expanding list of tumor-specific gene mutations and rearrangements that characterize the novel “Ph

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Molecular Tests in Pancreatic Cancer: Critical Role of Molecular Testing, Expanding Access, and Adherence to the NCCN Guidelines for Pancreatic Cancer

Nirag Jhala, Jeffrey Petersen, and Darshana Jhala

diagnosis and their involvement in genomic testing has helped improve precision therapeutics for pancreatic adenocarcinoma. Recently, the WHO has also recommended that tumor mutational profiling can be performed on EUS-guided FNA/B and that it can help with