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Vishruth K. Reddy, Varsha Jain, Sriram Venigalla, William P. Levin, Robert J. Wilson II, Kristy L. Weber, Anusha Kalbasi, Ronnie A. Sebro, and Jacob E. Shabason

involving surgery, radiation oncology, medical oncology, radiology, and pathology. 2 NCCN Clinical Practice Guidelines in Oncology (NCCN Guidelines) for STS recommend the addition of neoadjuvant or adjuvant radiation therapy (RT) to surgery for patients

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Jordan E. Rullo and Sandhya Pruthi

preoperatively. 2 For women undergoing risk-reducing surgeries for elevated breast or ovarian cancer risk or hereditary predisposition, the impact on sexual health is one of the most influential factors when deciding to undergo these surgeries. 3 Among BRCA

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Andrea Cercek, Karyn A. Goodman, Carla Hajj, Emily Weisberger, Neil H. Segal, Diane L. Reidy-Lagunes, Zsofia K. Stadler, Abraham J. Wu, Martin R. Weiser, Philip B. Paty, Jose G. Guillem, Garrett M. Nash, Larissa K. Temple, Julio Garcia-Aguilar, and Leonard B. Saltz

those of local recurrence. 1 , 2 The current standard management for stage II (T3/T4N0) and stage III (TanyN1/N2) rectal cancer is neoadjuvant chemoradiotherapy, followed by surgery, with 4 months of adjuvant systemic chemotherapy given at the end. 1

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Quisette P. Janssen, Jacob L. van Dam, Laura R. Prakash, Deesje Doppenberg, Christopher H. Crane, Casper H.J. van Eijck, Susannah G. Ellsworth, William R. Jarnagin, Eileen M. O’Reilly, Alessandro Paniccia, Marsha Reyngold, Marc G. Besselink, Matthew H.G. Katz, Ching-Wei D. Tzeng, Amer H. Zureikat, Bas Groot Koerkamp, Alice C. Wei, and for the Trans-Atlantic Pancreatic Surgery (TAPS) Consortium

declare itself for patients with elevated tumor markers, thereby improving patient selection for surgery. 4 In the current NCCN Guidelines (Version 2.2021), neoadjuvant chemotherapy may be followed by radiotherapy (RT), without clear specification on

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Sandra O. Gollnick

treated with PDT or surgically removed. Both before and after PDT, “we saw an increased T-cell response against that Hip1 antigen that we did not see following surgery,” Dr. Gollnick reported. This systemic antitumor immune response was inversely

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Kan Wu, Xu Liu, Zhihong Liu, Yiping Lu, Xianding Wang, and Xiang Li

Background Adrenocortical carcinoma (ACC) is a rare but highly aggressive tumor with an estimated incidence of 0.7 to 2.0 per 1,000,000 adult individuals annually. 1 Radical surgery is still the mainstay treatment of patients with

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Deborah K. Armstrong, Ronald D. Alvarez, Jamie N. Bakkum-Gamez, Lisa Barroilhet, Kian Behbakht, Andrew Berchuck, Lee-may Chen, Mihaela Cristea, Maria DeRosa, Eric L. Eisenhauer, David M. Gershenson, Heidi J. Gray, Rachel Grisham, Ardeshir Hakam, Angela Jain, Amer Karam, Gottfried E. Konecny, Charles A. Leath III, Joyce Liu, Haider Mahdi, Lainie Martin, Daniela Matei, Michael McHale, Karen McLean, David S. Miller, David M. O’Malley, Sanja Percac-Lima, Elena Ratner, Steven W. Remmenga, Roberto Vargas, Theresa L. Werner, Emese Zsiros, Jennifer L. Burns, and Anita M. Engh

Overview Primary treatment of presumed ovarian, fallopian tube, or primary peritoneal cancer usually consists of appropriate surgical staging and debulking surgery, followed in most (but not all) patients by systemic chemotherapy (OV-1, OV-4, above

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Angela W Zhang, Camille M Powers, Kathryn E Gallaway, and Alexandra K Callan

Background : Leg length discrepancy (LLD) is a potential long-term complication in skeletally immature patients with lower extremity bone tumors undergoing limb salvage surgery. Surgical reconstruction violates the epiphyseal plates around the

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Joyce Valerie Veld, Femke Julie Amelung, Wernard Aat Antoine Borstlap, Emo Eise van Halsema, Esther Catharina Josephina Consten, Peter Derk Siersema, Frank ter Borg, Edwin Silvester van der Zaag, Paul Fockens, Willem Adrianus Bemelman, Jeanin Elise van Hooft, Pieter Job Tanis, and for the Dutch Snapshot Research Group

postoperative morbidity and mortality. 1 Initial decompression of a distended colon as a bridge to surgery (BTS) is likely to change the risk profile of the patient, but it requires an additional intervention with its own disadvantages. The construction of a