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Preventive Health in Cancer Survivors: What Should We Be Recommending?

Linda S. Overholser and Carlin Callaway

cause of death for adults in the US general population, is now known to be a leading cause of death in individuals treated for cancer. 7 – 12 As with cancer, CVD in survivors could be due to common behavioral risk factors, a family history, a late

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What’s in a Number? Examining the Prognostic and Predictive Importance of Platelet Count in Patients With Essential Thrombocythemia

Andrew T. Kuykendall and Rami Komrokji

corresponding risk category being assigned. 2 – 4 Additional risk factors have been proposed but not universally incorporated into risk-stratification models, including cardiovascular risk factors, leukocytosis, and, perhaps most controversially, platelet count

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Prevention and Treatment of Cancer-Related Infections

Lindsey Robert Baden, William Bensinger, Michael Angarone, Corey Casper, Erik R. Dubberke, Alison G. Freifeld, Ramiro Garzon, John N. Greene, John P. Greer, James I. Ito, Judith E. Karp, Daniel R. Kaul, Earl King, Emily Mackler, Kieren A. Marr, Jose G. Montoya, Ashley Morris-Engemann, Peter G. Pappas, Ken Rolston, Brahm Segal, Susan K. Seo, Sankar Swaminathan, Maoko Naganuma, and Dorothy A. Shead

risk factor for the development of infections in patients undergoing chemotherapy. Effective strategies to anticipate, prevent, and manage infectious complications in neutropenic patients with cancer have led to improved outcomes. 1 – 12 Because of

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Managing Pain in Patients and Survivors: Challenges Within the United States Opioid Crisis

Judith A. Paice

. “For goal-setting surrounding pain, the focus has shifted from looking for zero on a pain scale to improving patients’ function. For a thorough assessment, we need to ask patients about risk factors for misuse. Family history is a crude proxy for risk

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Advances in Supportive Care for Multiple Myeloma

Noopur S. Raje, Andrew J. Yee, and G. David Roodman

3.7 years. 35 Dental extractions are a major risk factor for the development of ONJ. 34 , 36 Attention to dental hygiene and minimizing invasive procedures (eg, tooth extractions, dental implants) may reduce the risk of ONJ. 37 IMWG guidelines

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Mammographic Breast Density: Effect on Imaging and Breast Cancer Risk

Renee W. Pinsky and Mark A. Helvie

area of tissue is known as percent mammographic density ( PMD ). Breast Density Measurement Recognition of breast density as a breast cancer risk factor and measurement of density have been evolving for more than 30 years. This affects a large number

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Role of Laparoscopic Surgery in the Management of Endometrial Cancer

Meaghan Tenney and Joan L. Walker

RJ . Relationship between surgical-pathological risk factors and outcome in clinical stage I and II carcinoma of the endometrium: a Gynecologic Oncology Group study . Gynecol Oncol 1991 ; 40 : 55 – 65 . 5 FIGO . Corpus cancer staging

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Opioid Misuse and Abuse: Risk Assessment and Management in Patients with Cancer Pain

Doralina L. Anghelescu, Jennifer Harman Ehrentraut, and Lane G. Faughnan

Treatment of chronic pain with opioids is associated with the risk of abuse, misuse, diversion, and addiction. 1 Patients receiving chronic opioid therapy (COT) for malignant or nonmalignant pain should be assessed for risk factors of abuse and

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Multidisciplinary Management of Locally Advanced Rectal Cancer: Neoadjuvant Approaches

Swaminathan Murugappan, William P. Harris, Christopher G. Willett, and Edward Lin

cancer, requiring specific multimodality approaches. This article reviews the biology, risk factors, and evolving treatment of LARC. Important advances have been made in the past 3 decades in the multimodality treatment of patients with LARC. In the

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Myelodysplastic Syndromes, Version 2.2015

Peter L. Greenberg, Richard M. Stone, Rafael Bejar, John M. Bennett, Clara D. Bloomfield, Uma Borate, Carlos M. De Castro, H. Joachim Deeg, Amy E. DeZern, Amir T. Fathi, Olga Frankfurt, Karin Gaensler, Guillermo Garcia-Manero, Elizabeth A. Griffiths, David Head, Virginia Klimek, Rami Komrokji, Lisa A. Kujawski, Lori J. Maness, Margaret R. O’Donnell, Daniel A. Pollyea, Bart Scott, Paul J. Shami, Brady L. Stein, Peter Westervelt, Benton Wheeler, Dorothy A. Shead, and Courtney Smith

DNMT3A, U2AF1, SRSF2, CBL, PRPF8, SETBP1 , and KRAS . 23 , 26 , 29 – 32 Mutations of SF3B1 have been associated with a more favorable prognosis, but this may not be an independent risk factor. 26 , 33 Mutations of TP53 are strongly associated