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Improving Outcomes of Acute Promyelocytic Leukemia in the Current Era: Analysis of the SEER Database

Guru Subramanian Guru Murthy, Aniko Szabo, Laura Michaelis, Karen-Sue Carlson, Lyndsey Runaas, Sameem Abedin, and Ehab Atallah

), and other agents, has remarkably transformed the outcomes of this disorder, with current cure rates exceeding 90%. 2 – 5 However, this result is often a projection of data from clinical trials that included carefully selected patients and may not

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Randomized Trial of a Palliative Care Intervention to Improve End-of-Life Care Discussions in Patients With Metastatic Breast Cancer

Joseph A. Greer, Beverly Moy, Areej El-Jawahri, Vicki A. Jackson, Mihir Kamdar, Juliet Jacobsen, Charlotta Lindvall, Jennifer A. Shin, Simone Rinaldi, Heather A. Carlson, Angela Sousa, Emily R. Gallagher, Zhigang Li, Samantha Moran, Magaret Ruddy, Maya V. Anand, Julia E. Carp, and Jennifer S. Temel

/caregiver or oncologist. When these patients received PC, they did not follow the intervention protocol. Study Measures Documentation of EoL Care Preferences (Primary Outcome) To identify clinician documentation of EoL care discussions, we used

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Regional Radiation Therapy Impacts Outcome for Node-Positive Cutaneous Melanoma

Tobin Strom, Javier F. Torres-Roca, Akash Parekh, Arash O. Naghavi, Jimmy J. Caudell, Daniel E. Oliver, Jane L. Messina, Nikhil I. Khushalani, Jonathan S. Zager, Amod Sarnaik, James J. Mulé, Andy M. Trotti, Steven A. Eschrich, Vernon K. Sondak, and Louis B. Harrison

included. Demographic, histopathologic, radiation, and outcome data were reviewed. Patients were treated with either SLNB alone (n=49) or followed by completion LND (n=270) or therapeutic LND (n=91). Most patients with a known primary underwent wide

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Locally Advanced Colon Cancer: Evaluation of Current Clinical Practice and Treatment Outcomes at the Population Level

Charlotte E.L. Klaver, Lieke Gietelink, Willem A. Bemelman, Michel W.J.M. Wouters, Theo Wiggers, Rob A.E.M. Tollenaar, Pieter J. Tanis, and on behalf of the Dutch Surgical Colorectal Audit Group

Dutch Surgical Colorectal Audit (DSCA) has been evaluating and reporting on the quality of care of primary CRC surgery since 2009. 7 , 8 The goal of this study was to evaluate current clinical practice regarding and short-term outcomes of the treatment

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Screening and Stepped Care Targeting Psychological Distress in Patients With Metastatic Colorectal Cancer: The TES Cluster Randomized Trial

Claudia S.E.W. Schuurhuizen, Annemarie M.J. Braamse, Aartjan T.F. Beekman, Pim Cuijpers, Mecheline H.M. van der Linden, Adriaan W. Hoogendoorn, Hans Berkhof, Dirkje W. Sommeijer, Vera Lustig, Suzan Vrijaldenhoven, Haiko J. Bloemendal, Cees J. van Groeningen, Annette A. van Zweeden, Maurice J.D.L. van der Vorst, Ron Rietbroek, Cathrien S. Tromp-van Driel, Machteld N.W. Wymenga, Peter W. van der Linden, Aart Beeker, Marco B. Polee, Erdogan Batman, Maartje Los, Aart van Bochove, Jan A.C. Brakenhoff, Inge R.H.M. Konings, Henk M.W. Verheul, and Joost Dekker

interventions and social support for patients with diagnosed distress have been shown to be effective, 7 – 11 but so far no conclusive evidence shows that the combination of screening and subsequent treatment of distress actually improves patient outcomes

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Risk of Cardiovascular Diseases Among Older Breast Cancer Survivors in the United States: A Matched Cohort Study

Anthony A. Matthews, Sharon Peacock Hinton, Susannah Stanway, Alexander R. Lyon, Liam Smeeth, Krishnan Bhaskaran, and Jennifer L. Lund

focusing on composite cardiovascular outcomes. 4 – 13 Before attempting to fully understand the mechanisms behind changes in cardiovascular risk in women diagnosed with breast cancer, there is a pressing need for evidence on associations between breast

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Treatment Patterns and Survival Outcomes in Patients With Breast Cancer on Medicaid, Pre- and Post-Expansion

Siran M. Koroukian, Weichuan Dong, Jeffrey M. Albert, Uriel Kim, Kirsten Eom, Johnie Rose, Cynthia Owusu, Kristine M. Zanotti, Gregory Cooper, and Jennifer Tsui

expansion the opportunity to join the program. Breast cancer is the second most common cancer in women, claiming >40,000 lives annually. 3 Prior studies comparing breast cancer treatment patterns and outcomes before and after Medicaid expansion have

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Patient-Defined Goals and Preferences Among Adults With Advanced Neuroendocrine Tumors

Daneng Li, Can-Lan Sun, Heeyoung Kim, Christiana Crook, Ya-Han Zhang, Rebecca Allen, Richard Ballena, Shadman Hyder, Marianna Koczywas, Vincent Chung, Dean Lim, Vani Katheria, William Dale, and Gagandeep Singh

and symptom relief, another study of older adults with solid tumors starting chemotherapy suggested that older adults may value other outcomes instead of survival. 11 The role of patient preferences in NETs has not yet been studied. Clinical trials

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Outcomes of COVID-19 in Patients With a History of Cancer and Comorbid Cardiovascular Disease

Sarju Ganatra, Sourbha S. Dani, Robert Redd, Kimberly Rieger-Christ, Rushin Patel, Rohan Parikh, Aarti Asnani, Vigyan Bang, Katherine Shreyder, Simarjeet S. Brar, Amitoj Singh, Dhruv S. Kazi, Avirup Guha, Salim S. Hayek, Ana Barac, Krishna S. Gunturu, Corrine Zarwan, Anne C. Mosenthal, Shakeeb A. Yunus, Amudha Kumar, Jaymin M. Patel, Richard D. Patten, David M. Venesy, Sachin P. Shah, Frederic S. Resnic, Anju Nohria, and Suzanne J. Baron

the highest risk of mortality. 1 – 8 Although both cancer and CVD have been independently associated with higher COVID-19–associated adverse outcomes, outcomes for patients with COVID-19 afflicted with a dual diagnosis of cancer and

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Randomized Trial of a Smartphone Mobile App to Improve Symptoms and Adherence to Oral Therapy for Cancer

Joseph A. Greer, Jamie M. Jacobs, Nicole Pensak, Lauren E. Nisotel, Joel N. Fishbein, James J. MacDonald, Molly E. Ream, Emily A. Walsh, Joanne Buzaglo, Alona Muzikansky, Inga T. Lennes, Steven A. Safren, William F. Pirl, and Jennifer S. Temel

survival. 10 – 14 Despite its importance for optimal outcomes, adherence to these medications varies widely, with rates ranging from as high as 100% to <50%. 15 – 18 A variety of patient-, clinician-, treatment-, and healthcare system–related factors are