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NCCN Guidelines Updates: Prostate Cancer and Prostate Cancer Early Detection

Peter H. Carroll and James L. Mohler

men with high-risk, very high-risk, regional, or metastatic prostate cancer. Men with BRCA1 /2, ATM, PALB2 , or FANCA should be referred for genetic counseling and early use of platinum chemotherapy, or consider enrollment on a clinical trial. 2

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Genetic/Familial High-Risk Assessment: Breast and Ovarian, Version 1.2014

Mary B. Daly, Robert Pilarski, Jennifer E. Axilbund, Saundra S. Buys, Beth Crawford, Susan Friedman, Judy E. Garber, Carolyn Horton, Virginia Kaklamani, Catherine Klein, Wendy Kohlmann, Allison Kurian, Jennifer Litton, Lisa Madlensky, P. Kelly Marcom, Sofia D. Merajver, Kenneth Offit, Tuya Pal, Boris Pasche, Gwen Reiser, Kristen Mahoney Shannon, Elizabeth Swisher, Nicoleta C. Voian, Jeffrey N. Weitzel, Alison Whelan, Georgia L. Wiesner, Mary A. Dwyer, and Rashmi Kumar

emphasized that these guidelines were not developed as a substitute for professional genetic counseling. Rather, they are intended to serve as a resource for health care providers to identify individuals who may benefit from cancer risk assessment and genetic

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Advancing the Standard of Cancer Care in 2014

Robert W. Carlson

and supportive care topics. For example, this special edition includes a presentation on “Genetic Counseling in Patients with Familial Risk for Colorectal Cancer,” a topic that was translated into new NCCN Guidelines for Genetic/Familial High

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Hope for a Future Free of Unconscious Biases and Racial Anxiety in Cancer Care

Elliot A. Asare and Oluwadamilola M. Fayanju

, receive palliative care consultation, or be referred for genetic counseling. 5 Although we can actively mitigate our conscious biases, our unconscious or implicit biases, defined as “attitudes and beliefs about race, ethnicity, age, ability, gender, or

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Point: Justification for Lynch Syndrome Screening Among All Patients With Newly Diagnosed Colorectal Cancer

Heather Hampel

their relatives to undergo genetic counseling and testing to learn if they too are at increased risk for cancer and could benefit from intensive cancer surveillance. The costs of screening can be offset by the benefits of cancer prevention in the patient

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Ovarian Clear Cell Carcinoma in Cowden Syndrome

Kevin Yauy, Marion Imbert-Bouteille, Virginie Bubien, Clothilde Lindet-Bourgeois, Gauthier Rathat, Helene Perrochia, Gaëtan MacGrogan, Michel Longy, Didier Bessis, Julie Tinat, Stéphanie Baert-Desurmont, Maud Blanluet, Pierre Vande Perre, Karen Baudry, Pascal Pujol, and Carole Corsini

be a promising treatment strategy for this cancer. 24 , 25 Offering family genetic testing to relatives of the proband and subsequently setting up personalized medical management is a critical component of cancer genetic counseling. Interestingly

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Interpretation of Genetic Testing for Lynch Syndrome in Patients With Putative Familial Colorectal Cancer

Christina Rybak and Michael J. Hall

provide ongoing comprehensive genetic risk information to current and past patients. Although tumor testing and risk evaluation have become integral aspects of medical oncology care, the complete process of cancer genetic counseling, from the construction

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NCCN Guidelines Insights: Survivorship, Version 2.2020

Featured Updates to the NCCN Guidelines

Crystal S. Denlinger, Tara Sanft, Javid J. Moslehi, Linda Overholser, Saro Armenian, K. Scott Baker, Gregory Broderick, Wendy Demark-Wahnefried, Debra L. Friedman, Mindy Goldman, Norah Lynn Henry, Christine Hill-Kayser, Melissa Hudson, Nazanin Khakpour, Divya Koura, Allison L. McDonough, Michelle Melisko, Kathi Mooney, Halle C. F. Moore, Natalie Moryl, Tracey O’Connor, Electra D. Paskett, Chirayu Patel, Lindsay Peterson, William Pirl, M. Alma Rodriguez, Kathryn J. Ruddy, Lillie Shockney, Sophia Smith, Karen L. Syrjala, Amye Tevaarwerk, Phyllis Zee, Nicole R. McMillian, and Deborah A. Freedman-Cass

, with genetic counseling and testing as appropriate, is also recommended (see SURV-3 , page 1018). Conclusions Subsequent primary cancers and cardiovascular disease are 2 leading causes of death in cancer survivors. Risk of the former can be mitigated

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Modification and Implementation of NCCN Guidelines™ on Breast Cancer in the Middle East and North Africa Region

Omalkhair Abulkhair, Nagi Saghir, Lobna Sedky, Ahmed Saadedin, Heba Elzahwary, Neelam Siddiqui, Mervat Al Saleh, Fady Geara, Nuha Birido, Nadia Al-Eissa, Sana Al Sukhun, Huda Abdulkareem, Menar Mohamed Ayoub, Fawaz Deirawan, Salah Fayaz, Alaa Kandil, Sami Khatib, Mufid El-Mistiri, Dorria Salem, El Siah Hassan Sayd, Mohammed Jaloudi, Mohammad Jahanzeb, and William I. Gradishar

). Genetic Counseling for High-Risk Women Recommendations: Setup for infrastructure, genetic counselors, and nurses is encouraged and should be prepared along with laws to protect women and families with positive hereditary factors from discrimination at

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The Genetics of Hereditary Non-Polyposis Colorectal Cancer

Stephen B. Gruber and Wendy Kohlmann

and molecular genetics of hereditary nonpolyposis colorectal cancer (Lynch syndromes): Genetic counseling implications . Cancer Epidemiol Biomarkers Prev 1997 ; 6 : 987 – 991 .