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induction and consolidation therapy. On multivariate analysis, postconsolidation MRD status independently affected relapse rate, overall survival, and relapse-free survival ( P < .001, for all comparisons). 21 Vinditti et al., 22 , 23 recently confirmed

-dose therapy for patients with newly diagnosed localized or metastatic EWS (NCT00020566). After initial induction chemotherapy and local therapy, patients undergo risk-stratified consolidation therapy ( Figure 1 ). Patients who experience poor response (R2) are

consolidative therapy vs. maintenance therapy or observation for patients with oligometastatic non-small-cell lung cancer: long-term results of a multi-institutional, phase II, randomized study . J Clin Oncol 2019 ; 37 : 1558 – 1565 . 10.1200/JCO.19

patient with AML should involve, among other considerations, the assessment of outcomes with standard consolidation therapy. Although long-term remission rates with chemotherapy may approach 40% in some groups of adult patients, the standard chemotherapy

Cavo M Tacchetti P Patriarca F . Bortezomib with thalidomide plus dexamethasone compared with thalidomide plus dexamethasone as induction therapy before, and consolidation therapy after, double autologous stem-cell transplantation in newly diagnosed

, and consolidation therapy after, double autologous stem-cell transplantation in newly diagnosed multiple myeloma: a randomised phase 3 study . Lancet 2010 ; 376 : 2075 – 2085 . 12 Rajkumar SV Jacobus S Callander NS . Lenalidomide plus

grade 3 or 4 infection-related adverse events was significantly higher in patients receiving rituximab maintenance/consolidation therapy than in those undergoing observation (relative risk, 2.9; 95% CI, 1.21–3.27). 43 In long-term follow-up of the EORTC

. a complete remission, and then received 2 additional cycles as consolidation therapy. The patient then experienced disease relapse and achieved a second remission after treatment with high-dose cytarabine and vosaroxin followed by decitabine. He then

myeloid leukemia: a Southwest oncology group study (9031) . Blood 1998 ; 91 : 3607 – 3615 . 98 Heil G Hoelzer D Sanz MA . A randomized, double-blind, placebo-controlled, phase III study of filgrastim in remission induction and consolidation

. Consolidation therapy with low-dose thalidomide and prednisolone prolongs the survival of multiple myeloma patients undergoing a single autologous stem-cell transplantation procedure . J Clin Oncol 2009 ; 27 : 1788 – 1793 . 41 Barlogie B Tricot G