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CLO20-055: Optimal Timing of Radical Surgery From Diagnosis in Muscle Invasive Bladder Cancer (MIBC)

Saurabh Parasramka, Quan Chen, Bin Huang, Peng Wang, and Zin Myint

after diagnosis adversely effects survival outcomes. Neoadjuvant chemotherapy (NAC) has become the standard of care for appropriate patients, which delays definitive surgery. Optimal timing of surgery from the time of diagnosis is uncertain when done

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CLO22-051: Influence of Environmental Temperature on Pathological Complete Response and Overall Survival in Breast Cancer: A National Cancer Database Population-Based Study

Ashish Gupta, Kristopher Attwood, Kush Gupta, Asha Gandhi, Stephen Edge, Kazuaki Takabe, and Shipra Gandhi

CD8 + T Cells and higher immunosuppressive cells] than mice housed at 30°C. The incidence of cancer has been shown to be higher in colder climates. A pathologic complete response (pCR) following neoadjuvant chemotherapy (NAC) for early-stage breast

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CLO22-060: > 3 Courses of Neo-Adjuvant Chemotherapy (NACT) May Affect Outcomes of Advanced Ovarian Serous Adenocarcinoma Patients

Yunyun Liu, KKL Chan, and Hui Zhou

Purpose : Neoadjuvant chemotherapy (NACT) can reduce tumor burden, lower difficulty of surgery in advanced ovarian cancer. However, the option of NACT cycle is still highly controversial. This paper intends to explore whether the number of NACT

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CLO21-024: Serial Circulating Tumor DNA Analysis for Treatment Monitoring in an Inflammatory Triple-Negative Breast Cancer Patient

Urmeel Patel, Nicole Hook, Meenakshi Malhotra, Perry Olshan, Paul R. Billings, Alexey Aleshin, and Angel Rodriguez

patient underwent neoadjuvant chemotherapy with dose dense AC (ddAC) followed by paclitaxel. Following one month, the patient underwent radical mastectomy, followed by adjuvant treatment and periodic radiological imaging, along with circulating tumor DNA

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CLO23-032: Treatment of HER2+ Breast Cancer: A Retrospective of Disease Prognosis With Loss of HER2 Amplification on Residual Disease After Neoadjuvant Treatment in a Community Hospital Setting

Dariusz Uczkowski, Arunabh Sekhri, Shilpi Gupta, Leah Gendler, Krzysztof Misiukiewicz, Miles Levin, and Bonni Guerin

Background: Neoadjuvant chemotherapy (NAC) with Anti-Human Epidermal Growth Factor Receptor 2 (Anti-HER2) agents has increased rates of pathologic complete response (pCR) in stage II-III HER2+ breast cancer. Several retrospective studies have

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CLO24-092: Neoadjuvant Tyrosine Kinase Inhibitors (TKIs) Efficacy in EGFR Positive Stage III Non–Small Cell Lung Cancer (NSCLC): A Systematic Review and Meta-Analysis

John Kelvin Lalusis and John Lois Padayao

Background: Current treatment guidelines for potentially resectable stage IIIA NSCLC primarily include neoadjuvant chemotherapy with the goal of pathological downstaging and complete surgical resection. With favorable anti-tumor activity and

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CLO20-060: Factors Associated with the Uptake of Adjuvant Pertuzumab in Patients with Stage I-III HER2-positive Breast Cancer: The University of Colorado Cancer Center Experience

Ericson Stoen, Jodi Kagihara, Peter Kabos, Christine Fisher, and Jennifer R. Diamond

.01). Hormone receptor status and prior pathologic complete response to neoadjuvant chemotherapy (if given) did not correlate with P administration. Conclusions: In our study, the use of adjuvant P was common in high-risk patients including premenopausal women

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CLO20-050: Effect of Tumor Grade on Neoadjuvant Treatment Outcome in Esophageal Cancer

Jordan McDonald, Rutika Mehta, Sarah Hoffe, and Jose Pimiento

stage 1 disease were much less likely to receive neoadjuvant chemotherapy than those with stage 3 disease. Tumor grade was not significantly associated with treatment response (P=0.551), negative margin resection (P=0.252), disease recurrence (P=0

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CLO20-037: Time is On Our Side: Concomitant Needle Biopsy and Wire-Free Localization of Axillary Lymph Nodes May Decrease Redundant Preoperative Needle Localization in BI-RADS 5, 6 Breast Cancer Patients

Mary K. Hayes, Mayra Frau, Erica Bloomquist, and Heather Wright

Background: Accurate axillary lymph node (LN) staging impacts prognosis and treatment. Breast surgeons use pre- and post neoadjuvant chemotherapy (NACT) findings to plan extent of axillary LN surgery. NACT confers an excellent treatment response in

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Quality Indicators in the Management of Bladder Cancer

Jeffrey S. Montgomery, David C. Miller, and Alon Z. Weizer

-based neoadjuvant chemotherapy for patients with T2–T4 localized bladder cancer followed by radical cystectomy to optimize disease outcomes. 15 Perioperative Intravesical Chemotherapy Studies dating back to the early 1990s evaluated the use of immediate