once daily on days 1–5, 8–12, 15–19, and 22–26 in the absence of disease progression or unacceptable toxicity. Blood samples are collected periodically for correlative laboratory studies. Patients also undergo diffusion-weighted MRI for analysis of in
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Anisley Valenciaga, O. Hans Iwenofu, and Gabriel Tinoco
image of MRI showing hypointense large soft tissue mass (3.1 × 5.3 × 5.0 cm) in the right neck (yellow arrow) while patient was receiving pazopanib prior to radiation therapy. Following radiation, the patient experienced considerable pain in her
Arif Kamal, Tian Zhang, Steve Power, and P. Kelly Marcom
disease in asymptomatic patients. 4 This was further demonstrated by a recent meta-analysis showing that preoperative MRI did not reduce long-term breast cancer recurrence. 5 Furthermore, increased imaging can have inadequate specificity, leading to
Joshua K. Sabari, John V. Heymach, and Beth Sandy
permitted. Active CNS metastases: untreated or treated and progressing; measurable CNS metastases: ≥10 mm in longest diameter by contrast-enhanced MRI. Table 2. Meaningful Clinical Benefit of Mobocertinib in PPP and EXCLAIM Extension Cohorts 41
Angela K. Green, Deborah Korenstein, Carol Aghajanian, Brooke Barrow, Michael Curry, and Roisin E. O’Cearbhaill
surveillance imaging within our institution and not through an outside provider or hospital. Frequency of unique events for CT or MRI of the chest, abdomen, and/or pelvis in the year after completion of first-line chemotherapy was calculated for patients
Sapho X. Roodbeen, Marta Penna, Susan van Dieren, Brendan Moran, Paris Tekkis, Pieter J. Tanis, Roel Hompes, and on behalf of the International TaTME Registry Collaborative
patients on the staging MRI scan. Approximately two-thirds of patients received some form of NAT. After NAT, good tumor regression grade was reported in 46% of patients. A low anterior resection was performed in most patients (91%). Complete details on
David S. Ettinger, Wallace Akerley, Gerold Bepler, Matthew G. Blum, Andrew Chang, Richard T. Cheney, Lucian R. Chirieac, Thomas A. D'Amico, Todd L. Demmy, Ramaswamy Govindan, Frederic W. Grannis Jr., Thierry Jahan, David H. Johnson, Anne Kessinger, Ritsuko Komaki, Feng-Ming Kong, Mark G. Kris, Lee M. Krug, Quynh-Thu Le, Inga T. Lennes, Renato Martins, Janis O'Malley, Raymond U. Osarogiagbon, Gregory A. Otterson, Jyoti D. Patel, Katherine M. Pisters, Karen Reckamp, Gregory J. Riely, Eric Rohren, Scott J. Swanson, Douglas E. Wood, and Stephen C. Yang
function tests and MRI of the chest can also be done if clinically indicated. On CT, thymoma can look like malignant mesothelioma; however, pleural effusion does not typically occur with thymoma. Alpha-fetoprotein (AFP) and β–human chorionic gonadotropin (β
Juan Francisco Rodríguez-Moreno, María Apellaniz-Ruiz, Juan María Roldan-Romero, Ignacio Durán, Luis Beltrán, Cristina Montero-Conde, Alberto Cascón, Mercedes Robledo, Jesus García-Donas, and Cristina Rodríguez-Antona
palliative radiotherapy Figure 1. (A) Initial tumor dissemination detected by PET/CT (arrows). (B) MRI showing skull metastasis (arrow), which was surgically removed in 2015. for a painful right iliac metastasis and started sunitinib treatment
Surekha Yadav
imaging (CT/MRI) with 18F-FDG PETCT and to elaborate on the diagnostic accuracy of functional PET imaging over conventional imaging techniques. MATERIAL AND METHODS : An aggressive tumor of the young, Ewing sarcoma. Is around 15% of all bone tumors. We
So Kato
enough to impair structural integrity; OVF is caused by universal trabecular thinning that renders a vertebra unable to tolerate the physiologic load. MRI is considered the imaging modality with the strongest discriminant capability, enabling
