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localized gastric cancer. Postoperative chemotherapy plus chemoradiation is an alternative option for patients who received less than a D2 lymph node dissection .” GAST-F 3 of 16 First-Line Therapy; Useful in Certain Circumstances; HER2

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Michael D. Green and James A. Hayman

guidelines favor lymph node dissection more strongly in fit patients with clinically apparent disease versus those with clinically node-negative, SLNB-positive disease, but definitive RT can also be considered in both settings. The advantage of further

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Jeffrey J. Wargo, David R. Carr, Jose A. Plaza, and Claire F. Verschraegen

perform a radical lymph node dissection to reduce the tumor burden. On final pathology, the tumor was poorly differentiated, measuring 10 cm in maximum diameter, with 8 of 28 nodes positive for metastases and extranodal extension (2.5 cm in greatest

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Benjamin E. Greer and Wui-Jin Koh

evaluation and sentinel lymph node biopsy (SLNB) or bilateral inguinofemoral lymph node dissection (LND). Lateral lesions should have ipsilateral groin node evaluation plus SLNB or ispsilateral groin LND. LND is performed through a separate incision, Dr

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Daniel G. Coit and Anthony J. Olszanski

with lesions 0.76 to 1.0 mm, SLNB can be considered. For patients with lesions thicker than 1 mm, SLNB is recommended ( Figure 1 ). Patients with stage IIIA (sentinel lymph node-positive) disease should undergo completion lymph node dissection or be

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Ernest S. Han and Mark Wakabayashi

, pelvic and para-aortic lymph node dissection, and peritoneal biopsies and washings performed through a vertical midline incision. 2 – 4 When evidence of a metastatic tumor is present within the abdominal/pelvic cavity, tumor debulking is performed with

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Jaffer A. Ajani, James S. Barthel, Tanios Bekaii-Saab, David J. Bentrem, Thomas A. D'Amico, Prajnan Das, Crystal Denlinger, Charles S. Fuchs, Hans Gerdes, James A. Hayman, Lisa Hazard, Wayne L. Hofstetter, David H. Ilson, Rajesh N. Keswani, Lawrence R. Kleinberg, Michael Korn, Kenneth Meredith, Mary F. Mulcahy, Mark B. Orringer, Raymond U. Osarogiagbon, James A. Posey, Aaron R. Sasson, Walter J. Scott, Stephen Shibata, Vivian E. M. Strong, Mary Kay Washington, Christopher Willett, Douglas E. Wood, Cameron D. Wright, and Gary Yang

with positive margins, is acceptable for symptomatic palliation of bleeding in unresectable tumors. Palliative gastric resection should not be performed unless the patient is symptomatic and lymph node dissection is not required (page 386). Gastric

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Vivian E. Strong, Thomas A. D’Amico, Lawrence Kleinberg, and Jaffer Ajani

regarding the assignment of therapy: which patients should be considered to have a surgically curable tumor based on nodal status? Although various surgical approaches may be used, adequate lymph node dissection should accompany the resection, either a 2

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Melinda L. Telli, William J. Gradishar, and John H. Ward

. Patients with positive needle biopsy results for whom upfront surgery is planned have several options. The patient can proceed with an axillary lymph node dissection (ALND) or, if she meets all the ACOSOG Z0011 trial criteria 3 and also has low tumor

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Andrew K. Lee and Christopher L. Amling

surveillance. Preoperative knowledge of the probability of finding high-grade disease in the prostate specimen may also alter surgical technique or the decision to perform lymph node dissection. Chun et al. 18 , 19 developed 2 nomograms, one predicting Gleason