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Response Monitoring, Tolerability, and Effectiveness of Imatinib Treatment for Chronic Myeloid Leukemia in a Retrospective Research Database

David D. Stenehjem, Frederick Albright, Kuan-Ling Kuo, Karina Raimundo, Hillevi Bauer, Paul J. Shami, Michael W. Deininger, Lei Chen, and Diana I. Brixner

included patients older than 18 years at diagnosis between 2001 and 2010; an ICD-9 code indicative of CML (205.1, 205.10, 205.11, 205.12) and physician or laboratory-documented CP-CML; and use of imatinib as first-line CML therapy (initial cytoreduction

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The Role of Transplant in Multiple Myeloma

Matthew Mei and George Somlo

Conclusions Although much has been accomplished in the treatment of MM, the disease remains incurable, and patients with the highest-risk disease have a very poor prognosis. The benefit of additional cytoreduction afforded by either single or tandem ASCT is

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Variation in National Use of Long-Term ADT by Disease Aggressiveness Among Men With Unfavorable-Risk Prostate Cancer

Vinayak Muralidhar, Paul J. Catalano, Gally Reznor, Brandon A. Mahal, Toni K. Choueiri, Christopher J. Sweeney, Neil E. Martin, Clair J. Beard, Yu-Wei Chen, Michelle D. Nezolosky, Karen E. Hoffman, Felix Y. Feng, Quoc-Dien Trinh, and Paul L. Nguyen

– 2527 . 3. Hanks GE Pajak TF Porter A . Phase III trial of long-term adjuvant androgen deprivation after neoadjuvant hormonal cytoreduction and radiotherapy in locally advanced carcinoma of the prostate: the Radiation Therapy Oncology Group

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The Cost of Initial Care for Medicare Patients With Advanced Ovarian Cancer

Renata R. Urban, Hao He, Rafael Alfonso-Cristancho, Melissa M. Hardesty, and Barbara A. Goff

Wiechert A . Patient, treatment and discharge factors associated with hospital readmission within 30 days after surgical cytoreduction for epithelial ovarian carcinoma . Gynecol Oncol 2013 ; 130 : 407 – 410 . 27. FDA Draft Guidance on

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Local Therapies for Hepatic Metastases

Fabian M. Johnston, Michael N. Mavros, Joseph M. Herman, and Timothy M. Pawlik

-arterial therapy for NELM is more defined. Several studies have shown that intra-arterial therapy can help treat extensive intrahepatic disease and lead to cytoreduction of the disease and, in turn, hormone-related symptoms. 27 In one multi-institutional analysis

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Clinical Sequencing Contributes to a BRCA-Associated Cancer Rediagnosis That Guides an Effective Therapeutic Course

Jocelyn S. Chapman, Saurabh Asthana, Lindsay Cade, Matthew T. Chang, Zhen Wang, Charles J. Zaloudek, Stefanie Ueda, Eric A. Collisson, and Barry S. Taylor

cytoreduction to no visible disease and with minimal residual disease seen at surgery after completing 6 cycles of neoadjuvant chemotherapy. Although her pretreatment CA-125 was 4495 U/mL, this decreased to 37 U/mL after therapy and before Figure 2

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Hematopoietic Stem Cell Transplantation for Older Patients With Myelodysplastic Syndromes

H. Joachim Deeg and Marcos de Lima

. Nonmyeloablative stem cell transplantation and cell therapy as an alternative to conventional bone marrow transplantation with lethal cytoreduction for the treatment of malignant and nonmalignant hematologic diseases . Blood 1998 ; 91 : 756 – 763 . 52

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Healthcare Access Dimensions and Guideline-Concordant Ovarian Cancer Treatment: SEER-Medicare Analysis of the ORCHiD Study

Mary Katherine Montes de Oca, Lauren E. Wilson, Rebecca A. Previs, Anjali Gupta, Ashwini Joshi, Bin Huang, Maria Pisu, Margaret Liang, Kevin C. Ward, Maria J. Schymura, Andrew Berchuck, and Tomi F. Akinyemiju

OC, including cancer-directed surgery and chemotherapy. 3 – 8 National guidelines for the treatment of advanced-stage OC recommend surgical staging and cytoreduction plus systemic chemotherapy. 9 Maximal cytoreductive surgery correlates with

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Patient-Defined Goals and Preferences Among Adults With Advanced Neuroendocrine Tumors

Daneng Li, Can-Lan Sun, Heeyoung Kim, Christiana Crook, Ya-Han Zhang, Rebecca Allen, Richard Ballena, Shadman Hyder, Marianna Koczywas, Vincent Chung, Dean Lim, Vani Katheria, William Dale, and Gagandeep Singh

. Pancreatic cancer: a review . JAMA 2021 ; 326 : 851 – 862 . 10.1001/jama.2021.13027 34547082 42. Stewart CL , Warner S , Ito K , Cytoreduction for colorectal metastases: liver, lung, peritoneum, lymph nodes, bone, brain. When does it palliate

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Combined Androgen Blockade in Localized Prostate Cancer Treated With Definitive Radiation Therapy

Lucas K. Vitzthum, Chris Straka, Reith R. Sarkar, Rana McKay, J. Michael Randall, Ajay Sandhu, James D. Murphy, and Brent S. Rose

after neoadjuvant hormonal cytoreduction and radiotherapy in locally advanced carcinoma of the prostate: the Radiation Therapy Oncology Group protocol 92-02 . J Clin Oncol 2003 ; 21 : 3972 – 3978 . 10.1200/JCO.2003.11.023 14581419 11. Mostaghel EA