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vemurafenib and cobimetinib for 28 and 29 months, respectively—except for short breaks (18 and 10 days, respectively) due to rash and neutropenia—without clinical or radiologic changes ( Figure 1M, N ). Results of pathology, NGS, and partial MRI were published

neutropenia were collected and graded according to NCI Common Terminology Criteria for Adverse Events, version 4.1. Grade 1 neutropenia occurred in 15.5% of the patients (n=31), grade 2 in 31.5% (n=63), grade 3 in 38.5% (n=77), and grade 4 in 3% (n=6). Dose

-897 ), the first node in the “Yes” pathway for “Significant concerns about alopecia or neutropenia” should have read, “Platinum/ pemetrexed + bevacizumab” (page 894). The editorial office apologizes for this error. A corrected copy of the editorial is

, the NCCN Guidelines Panel initially established the febrile neutropenia threshold for use of myeloid growth factors at 20%; this standard has now been adopted by virtually all other guidelines committees. Moreover, it was the NCCN Panel who stressed

Overview Neutropenia (< 500 neutrophils/mcL or < 1000 neutrophils/mcL and a predicted decline to < 500/mcL over the next 48 hours) and resulting febrile neutropenia (≥ 38.3°C orally or ≥ 38.0°C over 1 hour) can be induced by myelosuppressive

neutropenia and fever] . Rev Esp Quimioter 2001 ; 14 : 75 – 83 . 3 Hughes WT Armstrong D Bodey GP . 2002 guidelines for the use of antimicrobial agents in neutropenic patients with cancer . Clin Infect Dis 2002 ; 34 : 730 – 751 . 4

INTRODUCTION : Myelosuppressive hematologic adverse events (HAEs; anemia, neutropenia, thrombocytopenia) are common complications of cytotoxic chemotherapy, a cornerstone of treatment for extensive-stage small cell lung cancer (ES-SCLC). This

in those who developed TLS. No significant association was found between Ven ramp up and TLS incidence. 42(37.8%) had known infections prior to starting HMA+Ven. 41 patients (36.9%) were diagnosed with febrile neutropenia; 36 (32.4%) had confirmed