presented at the annual meeting. Conclusions: The testing of molecularly targeted therapeutics in PDX models of pediatric solid tumors is feasible and may be beneficial to understanding the driver mutations and underlying biology of these malignancies. We
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YIA20-006: Preclinical Pediatric MATCH
Elizabeth Stewart, Kaley Blankenship, Lauren Hoffmann, and Burgess Freeman
EPR21-039: Socioeconomic Disparities in Receipt of Care in Lung Cancer
Evangelia Valilis, Catherine Yip, Laura Prichett, Catherine Burdalski, and Josephine Feliciano
care. This study aimed to evaluate the association of socio-demographic factors with lung cancer treatment at a large academic center that serves a diverse patient population. In the era of improved outcomes related to improved therapeutics such as
A “Shot Heard ’Round the World” on Cancer Drug Costs?
Harold J. Burstein
Recently, members of the pharmacy and therapeutics committee at Memorial Sloan-Kettering Cancer Center (MSKCC) in New York reported that MSKCC will not offer ziv-aflibercept (Zaltrap, Sanofi Oncology) to patients with advanced colorectal cancer at
The Time Has Come!
Margaret Tempero
When imatinib was approved by the FDA almost 20 years ago, a passionate prediction arose that, going forward, all targeted therapeutics would be approved without regard for the primary site of disease, based solely on the presumed molecular driver
NCCN Guidelines® Insights: Ovarian Cancer, Version 3.2022
Featured Updates to the NCCN Guidelines
Deborah K. Armstrong, Ronald D. Alvarez, Floor J. Backes, Jamie N. Bakkum-Gamez, Lisa Barroilhet, Kian Behbakht, Andrew Berchuck, Lee-may Chen, Viola C. Chitiyo, Mihaela Cristea, Maria DeRosa, Eric L. Eisenhauer, David M. Gershenson, Heidi J. Gray, Rachel Grisham, Ardeshir Hakam, Angela Jain, Amer Karam, Gottfried E. Konecny, Charles A. Leath III, Gary Leiserowitz, Joyce Liu, Lainie Martin, Daniela Matei, Michael McHale, Karen McLean, David S. Miller, Sanja Percac-Lima, Steven W. Remmenga, John Schorge, Daphne Stewart, Premal H. Thaker, Roberto Vargas, Andrea Wahner Hendrickson, Theresa L. Werner, Emese Zsiros, Mary A. Dwyer, and Lisa Hang
receiving consulting fees from Seagen Inc. David M. Gershenson, MD, Panel Member, has disclosed serving as a scientific advisor for Genentech, Inc., Onconova Therapeutics, and Verastem Oncology; owning equity interest/stock options in Bristol-Myers Squibb
Research Priorities in Geriatric Oncology: Addressing the Needs of an Aging Population
Arti Hurria, Supriya Gupta Mohile, and William Dale
rationale for these research directions. Cancer Therapeutics in the Oldest Adults (Ages 75 and Older) Among FDA-approved treatments for cancer, only 9% of patients enrolled in registration trials were 75 years or older, whereas 31% of patients with
Fatigue is the Most Important Symptom for Advanced Cancer Patients Who Have Had Chemotherapy
Zeeshan Butt, Sarah K. Rosenbloom, Amy P. Abernethy, Jennifer L. Beaumont, Diane Paul, Debra Hampton, Paul B. Jacobsen, Karen L. Syrjala, Jamie H. Von Roenn, and David Cella
, Bristol-Myers Squibb, Centocor, Cell Therapeutics, Inc., Genentech, GlaxoSmithKline, Eli Lilly and Company, Merck & Co., Novartis, Ortho Biotech, Pfizer, sanofi-aventis, and Takeda Pharmaceuticals. References 1. Cella DF Tulsky DS Gray G
Express Scripts? Really?
Margaret Tempero
Acorda Therapeutics, which is offered to patients free for 2 months before any charges begin. This model makes sense to me. I'm certainly not an expert in commercial enterprise, but I would think a company could shape a business model around this. And I
Oncology Research Program
metastatic head and neck squamous cell carcinoma (R/M HNSCC) has a dismal survival rate, and development of novel therapeutics has been met with little success. Although immunotherapeutics have shown promise in this devastating disease, most patients do not
Oncology Research Program
survival, and development of novel therapeutics has been met with little success. Although immunotherapeutics have shown promise in this devastating disease, most patients do not derive a benefit and a sizable population are not candidates for this therapy
