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Don’t Give Up – They Eventually Grow Up: Issues in AYA Medicine

Peter F. Coccia

?”; “You feel warm; let’s take your temperature.”; “You have a fever; we are going to the emergency room.” I further think that having a reliable support system (eg, mothers, spouses, significant others, friends) has a major influence on outcomes of therapy

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Notes From the Other Side

Margaret Tempero

something this simple, just think about how difficult it must be for our patients to master the pharmacopeia required for complex chemotherapy or symptom management drugs, not to mention remembering what to do in case of fever or a myriad of other

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Summary and Comparison of Myeloid Growth Factor Guidelines in Patients Receiving Cancer Chemotherapy

Gary H. Lyman and Jessica Malone Kleiner

– 4311 . 7. Crawford J Ozer H Stoller R . Reduction by granulocyte colony-stimulating factor of fever and neutropenia induced by chemotherapy in patients with small-cell lung cancer . N Engl J Med 1991 ; 325 : 164 – 170 . 8

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Safety at the Time of the COVID-19 Pandemic: How to Keep Our Oncology Patients and Healthcare Workers Safe

Pelin Cinar, Timothy Kubal, Alison Freifeld, Asmita Mishra, Lawrence Shulman, James Bachman, Rafael Fonseca, Hope Uronis, Dori Klemanski, Kim Slusser, Matthew Lunning, and Catherine Liu

symptoms such as a new or worsening cough within the past 14 days, shortness of breath, muscle aches, or fever, and may also include assessment of exposure risk, including travel history or exposure to a COVID-19–positive individual. If any concerning

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Antimicrobial Stewardship in Cancer Patients: The Time is Now

Samuel L. Aitken, Jerod L. Nagel, Lilian Abbo, William Alegria, Jason N. Barreto, Sanjeet Dadwal, Alison G. Freifeld, Rupali Jain, Steven A. Pergam, Frank P. Tverdek, Susan K. Seo, and on behalf of the Antimicrobial Stewardship in Cancer Consortium ASCC

-specific, evidence-based guidelines and clinical pathways to standardize prescribing is not only feasible but necessary. Examples of highly used pathways in patients with cancer include the management of fever and neutropenia, antifungal prophylaxis and treatment

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Guidelines of the National Comprehensive Cancer Network on the Use of Myeloid Growth Factors with Cancer Chemotherapy: A Review of the Evidence

Gary H. Lyman

R . Reduction by granulocyte colony-stimulating factor of fever and neutropenia induced by chemotherapy in patients with small-cell lung cancer . N Engl J Med 1991 ; 325 : 164 – 170 . 18 Trillet-Lenoir V Green J Manegold C

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Importance of Risk Factors for Febrile Neutropenia Among Patients Receiving Chemotherapy Regimens Not Classified as High-Risk in Guidelines for Myeloid Growth Factor Use

Derek Weycker, Xiaoyan Li, Rich Barron, Hongsheng Wu, P.K. Morrow, Hairong Xu, Maureen Reiner, Jacob Garcia, Shivani K. Mhatre, and Gary H. Lyman

Background Neutropenia is a common side effect of myelosuppressive chemotherapy that increases the risk of infection, which is typically signaled by fever. When neutropenic patients develop fever (ie, febrile neutropenia [FN]), the likelihood

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Infusion-Compatible Antibiotic Formulations for Rapid Administration to Improve Outcomes in Cancer Outpatients With Severe Sepsis and Septic Shock: The Sepsis STAT Pack

Jason D. Goldman, Amelia Gallaher, Rupali Jain, Zach Stednick, Manoj Menon, Michael J. Boeckh, Paul S. Pottinger, Stephen M. Schwartz, and Corey Casper

uncomplicated neutropenic fever, but differ regarding which antibiotics should be included in combination therapy for initial management of SS/SSh, reflecting sparse and conflicting data in patients with cancer and SS/SSh. We reasoned that intervening in the

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Long-Term Outcomes of Myeloid Growth Factor Treatment

Gary H. Lyman and David C. Dale

( ELANE ). 21 , 22 Patients with cyclic neutropenia have oscillations in blood neutrophils usually at 3-week intervals, measured from nadir to nadir. During the period of most severe neutropenia, fever, severe mouth ulcers, pharyngitis, sinusitis, anal

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fevers, sweats, weight loss, and pneumonia. A surgical biopsy is often required to effectively diagnose a patient with mesothelioma according to Dr. Krug. PET scans can aid in staging as well, detecting unexpected metastases in 10 percent of cases