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Yuan-Yuan Lei, Suzanne C. Ho, Ashley Cheng, Carol Kwok, Chi-Kiu Iris Lee, Ka Li Cheung, Roselle Lee, Herbert H.F. Loong, Yi-Qian He, and Winnie Yeo

-specific HRQoL issues relevant to a broad spectrum of patients with cancer. 30 The QLQ-C30 included a global health and QoL domain, 5 functional domains (physical, role, emotional, cognitive, and social), 3 symptom domains (fatigue, nausea and vomiting, and pain

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Rodger J. Winn

-controlled trial . J Clin Oncol 2001 ; 19 : 2865 - 2874 . 2 Berndt E Kallich J McDermott A . Reductions in anaemia and fatigue are associated with improvements in productivity in cancer patients receiving chemotherapy . Pharmacoeconomics 2005 ; 23

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Kevin O’Brien, Rahul Dave, Skand Shekhar, Fady Hannah-Shmouni, Leora E. Comis, Beth I. Solomon, Marcus Chen, William A. Gahl, Edmond FitzGibbon, Bernadette R. Gochuico, and Juvianee I. Estrada-Veras

, in combination with ostalgia, fatigue, and asthenia, can create balance, gait, and gross and fine motor coordination difficulties. 22 Deficits can range from mild issues resulting in subtle changes that can be readily addressed with occupational

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Nisar Ahmad, Denise M. Adams, Jiang Wang, Rajan Prakash, and Nagla Abdel Karim

past medical history presented with right upper quadrant abdominal pain, fatigue, poor appetite, and an approximately 20-lb weight loss over 2 to 3 months. She denied alcohol or illicit drug use. She had smoked half a pack of cigarettes per day for many

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Amy A. Kirkham, Riggs J. Klika, Tara Ballard, Paul Downey, and Kristin L. Campbell

A review of randomized controlled trials by a panel of clinical and research experts confirmed that during and after cancer treatment, exercise is safe and beneficial for reducing many common sequelae of cancer treatment, such as fatigue

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William G. Wierda, John C. Byrd, Jeremy S. Abramson, Seema Bhat, Greg Bociek, Danielle Brander, Jennifer Brown, Asher Chanan-Khan, Steve E. Coutre, Randall S. Davis, Christopher D. Fletcher, Brian Hill, Brad S. Kahl, Manali Kamdar, Lawrence D. Kaplan, Nadia Khan, Thomas J. Kipps, Jeffrey Lancet, Shuo Ma, Sami Malek, Claudio Mosse, Mazyar Shadman, Tanya Siddiqi, Deborah Stephens, Nina Wagner, Andrew D. Zelenetz, Mary A. Dwyer, and Hema Sundar

, HCL is characterized by symptoms of fatigue and weakness, and most patients will present with splenomegaly (symptomatic or asymptomatic) and/or hepatomegaly, pancytopenia, and uncommonly peripheral lymphadenopathy. 2 Additionally, patients may also

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Namrata Vijayvergia, Prashant C. Shah, and Crystal S. Denlinger

study of JBR.10 participants, global QOL declined in both the observation and chemotherapy arms, with both groups experiencing high symptom burden related to fatigue and postsurgical pain. A higher proportion of patients in the observation arm reported

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Daniel C. McFarland, Kelly M. Shaffer, Heather Polizzi, John Mascarenhas, Marina Kremyanskaya, Jimmie Holland, and Ronald Hoffman

physical symptom burden that has been shown to adversely affect their quality of life and psychological outcomes. 2 , 3 Although it is known that patients with MPNs report frequent fatigue, early satiety, or pruritus depending on their MPN type and

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Alexandra K. Zaleta, Melissa F. Miller, Julie S. Olson, Eva Y.N. Yuen, Thomas W. LeBlanc, Craig E. Cole, Shauna McManus, and Joanne S. Buzaglo

quality of life (QoL), including fatigue, pain, breathlessness, muscle weakness, and peripheral neuropathy, 11 , 12 which can negatively impact work, social, and familial roles. 13 Research has shown patients with MM experience greater symptom burden and

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Jesse D. Troy, Carlos M. de Castro, Mary Ruth Pupa, Greg P. Samsa, Amy P. Abernethy, and Thomas W. LeBlanc

patient-reported distress might correlate with disease activity, given that it reflects how patients are feeling, perhaps beyond what is measurable in routine laboratory assessments (eg, fatigue is known to correlate poorly with hemoglobin levels). 12