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Jay Gong, Jeffrey P. Gregg, Weijie Ma, Ken Yoneda, Elizabeth H. Moore, Megan E. Daly, Yanhong Zhang, Melissa J. Williams, and Tianhong Li

collapse (solid circle). (C–F) Histologic assessment of different lung pathologies. (C) Hematoxylin-eosin staining revealed LUAD at diagnosis and (D) invasive, well-differentiated, squamous cell carcinoma approximately 3.5 years later at the same location

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Kimberly Davies, Matthew Barth, Saro Armenian, Anthony N. Audino, Phillip Barnette, Branko Cuglievan, Hilda Ding, James B. Ford, Paul J. Galardy, Rebecca Gardner, Rabi Hanna, Robert Hayashi, Alexandra E. Kovach, Andrea Judit Machnitz, Kelly W. Maloney, Lianna Marks, Kristin Page, Anne F. Reilly, Joanna L. Weinstein, Ana C. Xavier, Nicole R. McMillian, and Deborah A. Freedman-Cass

-associated BL or DLBCL at this time. This discussion summarizes the NCCN Clinical Practice Guidelines in Oncology (NCCN Guidelines) for Pediatric Aggressive Mature B-Cell Lymphomas. These guidelines are intended to provide guidance regarding pathology and

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Wui-Jin Koh, Benjamin E. Greer, Nadeem R. Abu-Rustum, Susana M. Campos, Kathleen R. Cho, Hye Sook Chon, Christina Chu, David Cohn, Marta Ann Crispens, Don S. Dizon, Oliver Dorigo, Patricia J. Eifel, Christine M. Fisher, Peter Frederick, David K. Gaffney, Ernest Han, Susan Higgins, Warner K. Huh, John R. Lurain III, Andrea Mariani, David Mutch, Christa Nagel, Larissa Nekhlyudov, Amanda Nickles Fader, Steven W. Remmenga, R. Kevin Reynolds, Todd Tillmanns, Stefanie Ueda, Fidel A. Valea, Emily Wyse, Catheryn M. Yashar, Nicole McMillian, and Jillian Scavone

Squamous cell vulvar cancers are typically treated with primary surgery, with the potential integration of radiation (RT) and/or chemotherapy based on pathology and extent of disease. 14 Due to the high rates of morbidity with surgical treatment, the field

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L. Stewart Massad

, developed under the leadership of the American Society for Colposcopy and Cervical Pathology (ASCCP) in 2001 and 2006. 16 , 17 By extension, women with similar risk for CIN3 + based on other screening or triage tests also should undergo colposcopy. The

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Rachel L. Mitchell, Cory Kosche, Kelly Burgess, Shreya Wadhwa, Lela Buckingham, Ritu Ghai, Jacob Rotmensch, Oleksandra Klapko, and Lydia Usha

surgical debulking. Pathology was consistent with a high-grade serous carcinoma. Immunohistochemical staining was positive for TP53 ( Figure 2 ), WT-1, and ER. She received adjuvant chemotherapy with 6 cycles of carboplatin and paclitaxel. She remained

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Nadeem R. Abu-Rustum and Yukio Sonoda

evidence of metastasis. Sentinel node mapping was performed through cervical injection of blue dye with or without Technetium, as previously described. 14 Pathologic parameters were gathered from the final pathology report. Tumor diameter was estimated

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Leigh Selesner, Gabrielle Gauvin, Dorotea Mutabdzic, Eileen O’Halloran, Maxwell Kilcoyne, Kwan-Keat Ang, Jeffrey Farma, Elin Sigurdson, and Sanjay Reddy

. Diagnostic modality sensitivity and specificity were calculated by comparing findings on CT scan and DL to findings at the time of laparotomy and on final pathology. Specificity and sensitivity of the 2 modalities were compared using the McNemar Chi

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Jamie E. Flerlage, Susan M. Hiniker, Saro Armenian, Ellen C. Benya, Adam J. Bobbey, Vivian Chang, Stacy Cooper, Don W. Coulter, Branko Cuglievan, Bradford S. Hoppe, Leidy Isenalumhe, Kara Kelly, Leslie Kersun, Adam J. Lamble, Nicole A. Larrier, Jeffrey Magee, Kwadwo Oduro, Martha Pacheco, Anita P. Price, Kenneth B. Roberts, Christine M. Smith, Aliyah R. Sohani, Erin M. Trovillion, Emily Walling, Ana C. Xavier, Jennifer L. Burns, and Mallory Campbell

additional studies such as EBV serology and evaluation for underlying immunodeficiency. For additional information, see “Principles of Pathology” in the algorithm (see PHL-B 1 and 2 of 3, pages 742 and 743). The workup should include a thorough history and

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Laura J. Libby, Navneet Narula, Helen Fernandes, James F. Gruden, David J. Wolf, and Daniel M. Libby

Panel; Life Technologies, Inc., Grand Island, NY) showed that the patient harbored the KIT M541L variant in both the lymphangiomatosis and normal lung, suggesting the possibility of germline Figure 2. Surgical pathology. (A) Immunostain for D2

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Christopher K. Bichakjian, Thomas Olencki, Sumaira Z. Aasi, Murad Alam, James S. Andersen, Rachel Blitzblau, Glen M. Bowen, Carlo M. Contreras, Gregory A. Daniels, Roy Decker, Jeffrey M. Farma, Kris Fisher, Brian Gastman, Karthik Ghosh, Roy C. Grekin, Kenneth Grossman, Alan L. Ho, Karl D. Lewis, Manisha Loss, Daniel D. Lydiatt, Jane Messina, Kishwer S. Nehal, Paul Nghiem, Igor Puzanov, Chrysalyne D. Schmults, Ashok R. Shaha, Valencia Thomas, Yaohui G. Xu, John A. Zic, Karin G. Hoffmann, and Anita M. Engh

, 88 , 107 – 110 although a few studies have used other neuroendocrine markers. 111 Pathology Report Synoptic Reporting: Both historically and currently, consistent synoptic reporting of histopathologic parameters for MCCs is not widespread