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Abiy Agiro, Andrea DeVries, Jennifer Malin, and Michael J. Fisch

FN were identified by the presence of inpatient hospitalization or emergency department (ED) visit with an ICD-9 CM code for neutropenia (288.0) and fever (780.6) using previously validated claims-based algorithms (positive predictive value [PPV], 87

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John A. Thompson, Bryan J. Schneider, Julie Brahmer, Amaka Achufusi, Philippe Armand, Meghan K. Berkenstock, Shailender Bhatia, Lihua E. Budde, Saurin Chokshi, Marianne Davies, Amro Elshoury, Yaron Gesthalter, Aparna Hegde, Michael Jain, Benjamin H. Kaffenberger, Melissa G. Lechner, Tianhong Li, Alissa Marr, Suzanne McGettigan, Jordan McPherson, Theresa Medina, Nisha A. Mohindra, Anthony J. Olszanski, Olalekan Oluwole, Sandip P. Patel, Pradnya Patil, Sunil Reddy, Mabel Ryder, Bianca Santomasso, Scott Shofer, Jeffrey A. Sosman, Yinghong Wang, Vlad G. Zaha, Megan Lyons, Mary Dwyer, and Lisa Hang

outpatient transplant experience. Hospitalization is warranted for patients at the first sign of CRS or neurotoxicity, including fever, hypotension, or change in mental status. Complete blood count, complete metabolic panel (including magnesium and phosphorus

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Harold J. Burstein

scientific factors centered on cancer. A century ago, infectious disease was the specialty du jour. New technologies led to life-changing discoveries: the causes of exotic illnesses like yellow fever; the introduction of antibiotics (or as it was called early

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Peter F. Coccia

?”; “You feel warm; let’s take your temperature.”; “You have a fever; we are going to the emergency room.” I further think that having a reliable support system (eg, mothers, spouses, significant others, friends) has a major influence on outcomes of therapy

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Gary H. Lyman and Jessica Malone Kleiner

– 4311 . 7. Crawford J Ozer H Stoller R . Reduction by granulocyte colony-stimulating factor of fever and neutropenia induced by chemotherapy in patients with small-cell lung cancer . N Engl J Med 1991 ; 325 : 164 – 170 . 8

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Margaret Tempero

something this simple, just think about how difficult it must be for our patients to master the pharmacopeia required for complex chemotherapy or symptom management drugs, not to mention remembering what to do in case of fever or a myriad of other

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Pelin Cinar, Timothy Kubal, Alison Freifeld, Asmita Mishra, Lawrence Shulman, James Bachman, Rafael Fonseca, Hope Uronis, Dori Klemanski, Kim Slusser, Matthew Lunning, and Catherine Liu

symptoms such as a new or worsening cough within the past 14 days, shortness of breath, muscle aches, or fever, and may also include assessment of exposure risk, including travel history or exposure to a COVID-19–positive individual. If any concerning

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Gary H. Lyman

R . Reduction by granulocyte colony-stimulating factor of fever and neutropenia induced by chemotherapy in patients with small-cell lung cancer . N Engl J Med 1991 ; 325 : 164 – 170 . 18 Trillet-Lenoir V Green J Manegold C

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Samuel L. Aitken, Jerod L. Nagel, Lilian Abbo, William Alegria, Jason N. Barreto, Sanjeet Dadwal, Alison G. Freifeld, Rupali Jain, Steven A. Pergam, Frank P. Tverdek, Susan K. Seo, and on behalf of the Antimicrobial Stewardship in Cancer Consortium ASCC

-specific, evidence-based guidelines and clinical pathways to standardize prescribing is not only feasible but necessary. Examples of highly used pathways in patients with cancer include the management of fever and neutropenia, antifungal prophylaxis and treatment

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Gary H. Lyman and David C. Dale

( ELANE ). 21 , 22 Patients with cyclic neutropenia have oscillations in blood neutrophils usually at 3-week intervals, measured from nadir to nadir. During the period of most severe neutropenia, fever, severe mouth ulcers, pharyngitis, sinusitis, anal