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in the adjuvant chemotherapy of patients with node-positive primary breast cancer . 10 Schiff P Fant J Horowitz S . Promotion of microtubule assembly in vitro by taxol . Nature 1979 ; 227 : 665 – 667 . 11 Parness J Horoxitz

resection who have not undergone preoperative chemoradiation, capecitabine plus oxaliplatin was added as a category 2A adjuvant chemotherapy option following chemoradiation therapy with continuous 5-FU/RT or bolus 5-FU + leucovorin/RT or capecitabine

locoregional and distant failure. Chemoradiation is used to lower the rate of local recurrence, and adjuvant chemotherapy is used to lower the rate of both systemic and local recurrence. The initial principles of adjuvant chemotherapy were established before

in the right cerebellar hemisphere with hydrocephalus ( Figure 1E ). Complete Figure 1. (A) Posttherapy calcification of adrenalectomy and rare viable neuroblastoma cells showing good therapeutic response to adjuvant chemotherapy (hematoxylin

suggests there is a lot of room for improvement beyond just operating on these patients.” The 2008 Lung Adjuvant Cisplatin Evaluation (LACE) study, a pooled analysis of >4,500 patients from 5 largest trials of adjuvant chemotherapy in resected early

–IV ovarian cancer is the use of maintenance therapy after first-line primary/adjuvant chemotherapy. For patients who achieve a response after platinum-based first-line chemotherapy (± bevacizumab) for advanced disease, olaparib maintenance is a category 1

). In addition, the role of radiation in this disease is being further evaluated. Adjuvant Chemotherapy Adjuvant chemotherapy has not consistently been shown to improve overall survival in gastric cancer; Table 2 summarizes some of the early

among women receiving adjuvant chemotherapy for early-stage breast cancer who participated in a single-arm intervention trial of structured aerobic and resistance exercise programming compared with a historical cohort of similar patients who did not

adjuvant chemotherapy . Ann Surg 1982 ; 196 : 305 – 315 . 7 Potter DA Kinsella T Glatstein E . High-grade soft tissue sarcomas of the extremities . Cancer 1986 ; 58 : 190 – 205 . 8 Pisters PW Harrison LB Leung DH . Long

Background Over the past 50 years, substantial reductions in early breast cancer mortality have been documented due to a combination of earlier detection and to advances in adjuvant treatment. 1 – 4 In particular, adjuvant chemotherapy has