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Ronan J. Kelly

before and after surgery are widely used based on physician preference and access to radiation rather than compelling evidence favoring one approach over another. CRT followed by surgery is predominantly the preferred treatment in the United States, with

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Al B. Benson III, Alan P. Venook, Mahmoud M. Al-Hawary, Lynette Cederquist, Yi-Jen Chen, Kristen K. Ciombor, Stacey Cohen, Harry S. Cooper, Dustin Deming, Paul F. Engstrom, Jean L. Grem, Axel Grothey, Howard S. Hochster, Sarah Hoffe, Steven Hunt, Ahmed Kamel, Natalie Kirilcuk, Smitha Krishnamurthi, Wells A. Messersmith, Jeffrey Meyerhardt, Mary F. Mulcahy, James D. Murphy, Steven Nurkin, Leonard Saltz, Sunil Sharma, David Shibata, John M. Skibber, Constantinos T. Sofocleous, Elena M. Stoffel, Eden Stotsky-Himelfarb, Christopher G. Willett, Evan Wuthrick, Kristina M. Gregory, Lisa Gurski, and Deborah A. Freedman-Cass

rectal cancer surgery (ie, curative or palliative), consideration must also be given to the likely functional results of treatment, including the probability of maintaining or restoring normal bowel function/anal continence and preserving genitourinary

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Stanley J. Miller, Murad Alam, James S. Andersen, Daniel Berg, Christopher K. Bichakjian, Glen M. Bowen, Richard T. Cheney, L. Frank Glass, Roy C. Grekin, Alan L. Ho, Anne Kessinger, Nanette Liegeois, Daniel D. Lydiatt, Jeff Michalski, William H. Morrison, Kishwer S. Nehal, Kelly C. Nelson, Paul Nghiem, Thomas Olencki, Clifford S. Perlis, Ashok R. Shaha, Malika Tuli, Marshall M. Urist, Linda C. Wang, and John A. Zic

irregular and frequently deep subclinical extensions, every effort should be made to completely remove this tumor at initial therapy. If initial surgery yields positive margins, re-resection is recommended whenever possible, with the goal of achieving clear

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Margaret von Mehren, R. Lor Randall, Robert S. Benjamin, Sarah Boles, Marilyn M. Bui, Kristen N. Ganjoo, Suzanne George, Ricardo J. Gonzalez, Martin J. Heslin, John M. Kane III, Vicki Keedy, Edward Kim, Henry Koon, Joel Mayerson, Martin McCarter, Sean V. McGarry, Christian Meyer, Zachary S. Morris, Richard J. O'Donnell, Alberto S. Pappo, I. Benjamin Paz, Ivy A. Petersen, John D. Pfeifer, Richard F. Riedel, Bernice Ruo, Scott Schuetze, William D. Tap, Jeffrey D. Wayne, Mary Anne Bergman, and Jillian L. Scavone

Stage IV (synchronous metastatic disease) Recurrent disease General Principles Surgery Positive surgical margin is a strong predictor of local recurrence (LR) for patients with extremity STS. 23 – 28 Microscopically positive margins

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Soft Tissue Sarcoma, Version 2.2012

Featured Updates to the NCCN Guidelines

Margaret von Mehren, Robert S. Benjamin, Marilyn M. Bui, Ephraim S. Casper, Ernest U. Conrad III, Thomas F. DeLaney, Kristen N. Ganjoo, Suzanne George, Ricardo Gonzalez, Martin J. Heslin, John M. Kane III, Joel Mayerson, Sean V. McGarry, Christian Meyer, Richard J. O'Donnell, Benjamin Paz, John D. Pfeifer, Raphael E. Pollock, R. Lor Randall, Richard F. Riedel, Scott Schuetze, Karen D. Schupak, Herbert S. Schwartz, Sridhar Shankar, Brian A. Van Tine, Jeffrey Wayne, Hema Sundar, and Nicole R. McMillian

this study, among patients with primary resectable GIST, R0 resection (complete removal of all gross and microscopic disease) was performed in 77% of patients, and partial organ-preserving and function-preserving surgery was reported in most of these

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Margaret Tempero

surgery early on a Monday morning after enduring the usual preparations and feeling a bit apprehensive. Still, I was psyched; ready to go! As I waited for my call to pre-op, I received a call instead from the orthopedic resident. My surgery was cancelled

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Brent K. Hollenbeck, James E. Montie, and John T. Wei

. Invited commentary: Measurement of quality in surgery: that's our job . Surgery 2004 ; 135 : 576 – 578 . 9 Donaldson MS Nolan K . Measuring the quality of health care: state of the art . Jt Comm J Qual Improv 1997 ; 23 : 283 – 292

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Presenter: Christopher G. Willett

, Department of Radiation Oncology, Duke Cancer Institute. SCRT Versus Long-Course Chemoradiotherapy For patients with localized rectal cancer, SCRT is often given as 25 Gy in 5 fractions without concurrent chemotherapy and surgery performed within days of

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Jason P. Wilson, David Mattson, and Stephen B. Edge

Adjuvant Breast and Bowel Project (NSABP) B-04 trial showed no difference in survival among those treated with radical mastectomy (including axillary clearance), simple mastectomy plus radiation without axillary surgery, or simple mastectomy alone. 1 This

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Douglas E. Wood

testing and surgery, and the potential lack of true patient benefit due to lead-time and overdiagnosis bias. Yet many people have asked troubling questions about the prolonged lack of support for lung cancer early diagnosis, and some suggest that patients