, and by whom consent would be obtained in a population screening program remain unanswered. 7 , 9 , 13 Low provider knowledge of MSI/IHC and scarce genetic counseling resources 14 would likely leave many patients poorly informed about the
Search Results
Counterpoint: Implementing Population Genetic Screening for Lynch Syndrome Among Newly Diagnosed Colorectal Cancer Patients—Will the Ends Justify the Means?
Michael J. Hall
Clinical Sequencing Contributes to a BRCA-Associated Cancer Rediagnosis That Guides an Effective Therapeutic Course
Jocelyn S. Chapman, Saurabh Asthana, Lindsay Cade, Matthew T. Chang, Zhen Wang, Charles J. Zaloudek, Stefanie Ueda, Eric A. Collisson, and Barry S. Taylor
for genetic counseling, which revealed no family history of hereditable cancer. Plasma was sent for cell-free DNA (cfDNA) sequencing. 7 A baseline staging CT scan was obtained before the planned initiation of gemcitabine and nanoparticle albumin
QIM19-122: Quality Improvement Initiatives in the Second Year of an Adolescent and Young Adult Oncology Clinic
Heather Bowers, Kerri Susko, Aniket Saha, and Elizabeth Cull
Background: Adolescent and young adult (AYA) oncology patients have a distinctive set of needs that are often not addressed by primary providers in busy clinical practices. Genetic counseling, fertility preservation, clinical trial enrollment, and
Genetic Kidney Cancer Syndromes
Thai H. Ho and Eric Jonasch
testing of selected genes based on renal cell carcinoma (RCC) histology: (A) clear cell, (B) papillary type I, (C) papillary type II, and (D) chromophobe. Persons with RCC aged 46 years or younger should be considered for genetic counseling and germline
Current Approaches in Familial Colorectal Cancer: A Clinical Perspective
Patrick M. Lynch
Individuals with a family history of colorectal cancer or colorectal adenomas have an increased risk for colorectal cancer. When no hereditary syndrome is evident, screening is based on empiric risk estimates. The risk is greatest for individuals with specific inherited cancer-predisposing disorders. When conditions such as familial adenomatous polyposis or hereditary nonpolyposis colorectal cancer are diagnosed, specific neoplasm risk estimates can usually be performed based on advances in molecular genetics. These estimates lead to more straightforward and cost-effective approaches to surveillance and management. The National Comprehensive Cancer Center Network (NCCN) and other groups have provided detailed guidelines for evaluating patients based on recognition of clinical syndrome characteristics, followed by appropriate genetic counseling, genetic testing, and optimal surveillance. The NCCN guidelines are used as a frame of reference for this discussion of selected recent advances in human cancer genetics as they apply to clinical practice.
Your Genes: One Size Doesn't Fit All
Mary E. Freivogel and Stephanie A. Cohen
misconceptions about what she noted as an increasing workforce shortage in genetic counseling and, in fact, about the genetic counseling profession itself. Workforce shortages and barriers to care are common in many specialties in healthcare. 2 However
QIM21-082: Germline Testing in Pancreatic Adenocarcinoma: A Single Academic Center Experience
Veena Gujju, Mahum Nadeem, Hussein A. Assi, and Hassan Hatoum
patients with PDAC irrespective of family history. In this quality improvement project, we aim to report a single institution experience in implementing this new guideline, and thus provide real-world data on genetic counseling in clinical practice
Breast Cancer Risk Counseling: A Teachable Moment?
Mary Daly
. Genetic counseling is defined as the process of helping people understand and adapt to the medical, psychologic, and familial implications of genetic contributions to disease. The primary reasons cited by women who are considering genetic testing for
QIM20-129: Are You Ready? Assessing Readiness to Implement Quality Improvement in Hospitals Participating in a Breast Cancer Collaborative
Lindsey Kreutzer, Ashley Byerly, Eileen Ngo, Julie K. Johnson, Karl Y. Bilimoria, and Anthony D. Yang
documents. At the specialty/unit-level, perceptions of readiness to implement the QI project were strong, overall; however, one hospital unit (Genetic Counseling) identified a need to strengthen understanding of how the project would personally benefit
Molecular Tests in Pancreatic Cancer: Critical Role of Molecular Testing, Expanding Access, and Adherence to the NCCN Guidelines for Pancreatic Cancer
Nirag Jhala, Jeffrey Petersen, and Darshana Jhala
, significant challenges in adoption of universal germline testing and referral for genetic counseling for pancreatic adenocarcinoma continue. 2 , 3 These barriers could be a result of a combination of causes, including, but not limited to, the need for
