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David J. Worhunsky, Yifei Ma, Yulia Zak, George A. Poultsides, Jeffrey A. Norton, Kim F. Rhoads, and Brendan C. Visser

are more likely to have staging based on pathology specimens, whereas SS patients are more often staged clinically (ie, via imaging) without pathologic data. This is supported by the difference in the rate of surgery between the groups, with patients

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C. Anthony Blau, Arturo B. Ramirez, Sibel Blau, Colin C. Pritchard, Michael O. Dorschner, Stephen C. Schmechel, Timothy J. Martins, Elisabeth M. Mahen, Kimberly A. Burton, Vitalina M. Komashko, Amie J. Radenbaugh, Katy Dougherty, Anju Thomas, Christopher P. Miller, James Annis, Jonathan R. Fromm, Chaozhong Song, Elizabeth Chang, Kellie Howard, Sharon Austin, Rodney A. Schmidt, Michael L. Linenberger, Pamela S. Becker, Francis M. Senecal, Brigham H. Mecham, Su-In Lee, Anup Madan, Roy Ronen, Janusz Dutkowski, Shelly Heimfeld, Brent L. Wood, Jackie L. Stilwell, Eric P. Kaldjian, David Haussler, and Jingchun Zhu

Sequencing is performed at the University of Washington (UW) in the Departments of Pathology (WES and RNA-Seq) and Laboratory Medicine (UW-OncoPlex). WES and UW-OncoPlex are performed in accordance with Clinical Laboratory Improvement Amendments (CLIA

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Jeffrey S. Dome, Elizabeth A. Mullen, David B. Dix, Eric J. Gratias, Peter F. Ehrlich, Najat C. Daw, James I. Geller, Murali Chintagumpala, Geetika Khanna, John A. Kalapurakal, Lindsay A. Renfro, Elizabeth J. Perlman, Paul E. Grundy, and Conrad V. Fernandez

therapeutic trials, and to build a well-annotated tumor bank to enable basic and translational research. Submission of imaging studies, pathology slides, operative notes, and pathology reports was required within 14 days of initial surgical procedure for

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Thanh H. Dellinger, Amy A. Hakim, Stephen J. Lee, Mark T. Wakabayashi, Robert J. Morgan, and Ernest S. Han

Vulva with stage IA vulvar cancer with stromal invasion of ≤1 mm, treatment consists of a wide local excision without further adjuvant treatment for tumors with negative margins on final pathology. For tumors with >1 mm invasion and that are up to

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Rahul Aggarwal, Tian Zhang, Eric J. Small, and Andrew J. Armstrong

of primary NEPC, consisting of solid sheets of cells with large nuclei and abundant, eosinophilic cytoplasm. The Paneth cell subtype is identified on hematoxylin-eosin stained pathology sections based on its intense eosinophilic staining pattern with

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Parijatham S. Thomas

of atypical hyperplasia through its natural history: a longitudinal cohort study . Cancer Prev Res (Phila) 2014 ; 7 : 211 – 217 . 4. Bombonati A Sgroi DC . The molecular pathology of breast cancer progression . J Pathol 2011 ; 223

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Oxana Palesh, Arianna Aldridge-Gerry, Ayhan Ulusakarya, Elisabet Ortiz-Tudela, Lucile Capuron, and Pasquale F. Innominato

-wake systems results in a higher incidence of pathologies, such as accelerated aging, 8 metabolic syndrome, 9 and affective and cognitive impairments, 10 and also a higher incidence of cancer. 11 Immunity, Metabolic Regulation, and Sleep Strong

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Ronan J. Kelly

Harris CC . Pathology & Genetics: Tumours of the Lung, Pleura, Thymus and Heart . Lyon, France : IARC Press . 2004 : 146 – 248 . 5. Chen G Marx A Chen WH . New WHO histologic classification predicts prognosis of thymic epithelial tumors

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Gregory P. Kalemkerian, Billy W. Loo Jr, Wallace Akerley, Albert Attia, Michael Bassetti, Yanis Boumber, Roy Decker, M. Chris Dobelbower, Afshin Dowlati, Robert J. Downey, Charles Florsheim, Apar Kishor P. Ganti, John C. Grecula, Matthew A. Gubens, Christine L. Hann, James A. Hayman, Rebecca Suk Heist, Marianna Koczywas, Robert E. Merritt, Nisha Mohindra, Julian Molina, Cesar A. Moran, Daniel Morgensztern, Saraswati Pokharel, David C. Portnoy, Deborah Rhodes, Chad Rusthoven, Jacob Sands, Rafael Santana-Davila, Charles C. Williams Jr, Karin G. Hoffmann, and Miranda Hughes

extensive-stage disease, chemotherapy alone can palliate symptoms and prolong survival; however, long-term survival is rare. 11 For the 2018 update, the NCCN panel added a new section on pathology to the Guidelines (see SCL-B 1 of 2, page 1176). The WHO

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Joshua I. Warrick

Roupret M Yaxley J . Micropapillary urothelial carcinoma of the urinary bladder: a clinicopathological analysis of 72 cases . Pathology 2010 ; 42 : 650 – 654 . 11. Nigwekar P Tamboli P Amin MB . Plasmacytoid urothelial carcinoma: detailed