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Diagnosis and Treatment of Chordoma

Brian J. Williams, Daniel M.S. Raper, Erin Godbout, T. David Bourne, Daniel M. Prevedello, Amin B. Kassam, and Deric M. Park

extent of surgical resection and surgical margins. This article reviews the epidemiology, pathogenesis, presentation, diagnosis, and management of chordoma, and highlights future directions for potential therapy. Epidemiology Chordoma is a rare

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Mental Illness Stigma as a Barrier to Psychosocial Services for Cancer Patients

Alicia K. Matthews, Patrick W. Corrigan, and Judith Lee Rutherford

,” October 28–29, 2002 . Washington, D.C. : Institute of Medicine , 2002 . 10 Fawzy F Fawzy N Arnt L . Critical review of psychosocial interventions in cancer care . Arch Gen Psychiatry 1995 ; 52 : 100 – 113 . 11 Sparber A

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Oncology Research Program

scientific peer-review process and are overseen by the ORP. Several NCCN sponsored-studies funded through the grant mechanism are highlighted below. Impact of Temsirolimus Therapy on Circulating Tumor Cell Biology in Men with Castration

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Racial Background and Health Behaviors Among Adults With Cancer in Canada: Results of a National Survey

Omar Abdel-Rahman

the present analysis do indicate association rather causation, and further work is needed to confirm these results. These limitations need to be reviewed against the strengths of the present study, including its relatively big sample size, and the

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Next-Generation Sequencing: Role in Gynecologic Cancers

Tarra Evans and Ursula Matulonis

high-risk inherited genes, but its use in treatment remains limited. 5 , 6 This review discusses the impact of NGS on the understanding of molecular pathogenesis, cancer screening and prevention, diagnosis, and therapeutic strategies for gynecologic

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Soft Tissue Sarcoma, Version 2.2018, NCCN Clinical Practice Guidelines in Oncology

Margaret von Mehren, R. Lor Randall, Robert S. Benjamin, Sarah Boles, Marilyn M. Bui, Kristen N. Ganjoo, Suzanne George, Ricardo J. Gonzalez, Martin J. Heslin, John M. Kane III, Vicki Keedy, Edward Kim, Henry Koon, Joel Mayerson, Martin McCarter, Sean V. McGarry, Christian Meyer, Zachary S. Morris, Richard J. O'Donnell, Alberto S. Pappo, I. Benjamin Paz, Ivy A. Petersen, John D. Pfeifer, Richard F. Riedel, Bernice Ruo, Scott Schuetze, William D. Tap, Jeffrey D. Wayne, Mary Anne Bergman, and Jillian L. Scavone

were predictors of time to LR, but no difference in OS was seen. In a report from the Memorial Sloan Kettering Cancer Center that reviewed the long-term outcomes of 200 patients treated with limb-sparing surgery, pathologically negative re

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Fertility Preservation in Patients With Breast Cancer: Necessity, Methods, and Safety

Adrienne G. Waks and Ann H. Partridge

in this journal CE activity: 1) review the learning objectives and author disclosures; 2) study the education content; 3) take the posttest with a 66% minimum passing score and complete the evaluation at http://education.nccn.org/node/78105 ; and 4

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Chronic Lymphocytic Leukemia: Individualizing Treatment Approach

Andrew D. Zelenetz

. Frontline Setting Dr. Zelenetz briefly reviewed recent clinical trial data on some of the treatment options used for newly diagnosed CLL. He first discussed long-term data from 2 clinical trials that evaluated FCR (fludarabine

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Treatment of Metastatic Breast Cancer

William J. Gradishar

such as the pace of the disease, the patient’s overall medical condition, and comorbidities. Dr. Gradishar reviewed the current clinical data on endocrine therapy and strategies to overcome endocrine resistance, and discussed new agents used in

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Combined Modality Therapy of Localized Gastric and Esophageal Cancers

Prajnan Das, Norio Fukami, and Jaffer A. Ajani

Hafstrom L Glimelius B . Chemotherapy in gastric cancer: a review and updated meta-analysis . Eur J Surg 2002 ; 168 : 597 – 608 . 32. Hermans J Bonenkamp JJ Boon MC . Adjuvant therapy after curative resection for gastric cancer: meta