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Pazopanib Sensitivity in a Patient With Breast Cancer and FGFR1 Amplification

Fiona Tsui-Fen Cheng, Fu Ou-Yang, Nina Lapke, Kai-Che Tung, Yen-Kung Chen, Yuh-Yu Chou, and Shu-Jen Chen

was fatigue. After 3 months of treatment, therapeutic changes were evaluated by radiologic imaging. The most striking treatment effect was observed in the brain. Before treatment, tumors with internal calcifications and perifocal edema were observed in

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Advances in the Treatment of Non-Small Cell Lung Cancer

Leora Horn

was also seen in many patients, noted Dr. Horn. “There seemed to be no significant difference based on age, gender, performance status, histology, and molecular status,” she added. Fatigue was the most common adverse event reported with nivolumab

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A Change of Heart

Crystal S. Denlinger

, incorporating the outlined approach into practice is more straight-forward—discussing the receipt of age-appropriate vaccination or addressing issues such as pain or fatigue are daily aspects of a provider's routine clinical care. Other algorithms are more

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Systemic Therapy for Metastatic Colorectal Cancer

Leonard Saltz

more than half the patients derive no benefit, but the other half may obtain enough benefit to really matter,” he said. Fatigue can be a problem; starting treatment with a 25% dose reduction may be necessary to manage this, he noted, although he also

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Clinical Treatment Decisions for Advanced Renal Cell Cancer

Toni K. Choueiri

disease showed pazopanib to be non-inferior to sunitinib and to be associated with less hand-foot skin reaction, fatigue, stomatitis, and mucositis, though more liver function abnormalities and hair color changes. 5 Median PFS was 8.4 months with

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Targeted MAPK Pathway Inhibitors in Patients With Disseminated Pilocytic Astrocytomas

Anastasia Drobysheva, Laura J. Klesse, Daniel C. Bowers, Veena Rajaram, Dinesh Rakheja, Charles F. Timmons, Jason Wang, Korgun Koral, Lynn Gargan, Erica Ramos, and Jason Y. Park

combination therapy showed stable disease. The only reported adverse effect was fatigue. Patient 3 presented at 4 years of age with ataxia, hallucinations, and marked hydrocephalus associated with large midbrain PA and extensive intracranial and spinal

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Evolving Use of Androgen Deprivation Therapy in Prostate Cancer Management

James L. Mohler

was better, including erectile function, with intermittent ADT. 13 Toxicities associated with ADT include fatigue, hot flashes, loss of libido, osteoporosis, and metabolic syndrome, and there is an increased risk for stroke, myocardial infarction, and

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NCCN News

for supportive care areas including, but not limited to, adult cancer pain, antiemesis, cancer- and treatment-related anemia and infections, fatigue, distress management, palliative care, and survivorship. NCCN publishes a full library of 61 clinical

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Small Cell Lung Cancer in Light/Never Smokers – A Role for Molecular Testing?

Gordon Taylor Moffat, Tao Wang, and Andrew G. Robinson

nonproductive cough, shortness of breath, and fatigue. Initial assessment revealed decreased breath sounds in the left upper lobe (LUL) region and no palpable lymphadenopathy. Chest CT revealed a large necrotic LUL mass extending to the hilus and aortic arch

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NCCN Distress Thermometer Problem List Update

Kristine A. Donovan, George Handzo, Cheyenne Corbett, Jessica Vanderlan, Benjamin W. Brewer, and Kauser Ahmed

and fatigue were retained because nonpharmacologic interventions delivered by psychosocial professionals are known to be effective in relieving distress caused by these symptoms. 5 “Tobacco use” was added to distinguish it from other substances. The