knowledge regarding the typical characteristics of ICI-related esophagitis and the appropriate treatments for this condition. In this retrospective study, we aimed to characterize esophagitis associated with the use of ICIs and describe its clinical
Search Results
Clinicopathologic Features, Treatment Response, and Outcomes of Immune Checkpoint Inhibitor–Related Esophagitis
Kavea Panneerselvam, Rajan N. Amin, Dongguang Wei, Dongfeng Tan, Phillip J. Lum, Hao Chi Zhang, David M. Richards, Mehmet Altan, Petros Grivas, John A. Thompson, Anusha S. Thomas, and Yinghong Wang
Uptake of the 21-Gene Assay Among Women With Node-Positive, Hormone Receptor−Positive Breast Cancer
Megan C. Roberts, Allison W. Kurian, and Valentina I. Petkov
, including race, SES, and age, given the need to more deeply characterize test uptake in these groups over time. Population characteristics were analyzed using chi-square tests. Among those who received the 21-gene assay, kernel density estimates of the RS
Incident Cancer Detection During the COVID-19 Pandemic
Antoine Eskander, Qing Li, Jiayue Yu, Julie Hallet, Natalie G. Coburn, Anna Dare, Kelvin K.W. Chan, Simron Singh, Ambica Parmar, Craig C. Earle, Lauren Lapointe-Shaw, Monika K. Krzyzanowska, Timothy P. Hanna, Antonio Finelli, Alexander V. Louie, Nicole Look Hong, Jonathan C. Irish, Ian J. Witterick, Alyson Mahar, Christopher W. Noel, David R. Urbach, Daniel I. McIsaac, Danny Enepekides, and Rinku Sutradhar
. Data Sources The analysis was performed using data held at the ICES (previously known as the Institute for Clinical Evaluative Sciences). Demographic characteristics, vital status, and date of death for all individuals covered under the Ontario Health
Multiorgan Immune-Related Adverse Events During Treatment With Atezolizumab
Ganessan Kichenadasse, John O. Miners, Arduino A. Mangoni, Andrew Rowland, Ashley M. Hopkins, and Michael J. Sorich
outcomes. Baseline age, sex, race, tumor characteristics, serum lactate dehydrogenase and C-reactive protein (CRP) levels, lung immune prognostic index (LIPI), neutrophil-to-lymphocyte ratio, and various subpopulations of white cells were evaluated for
Allogeneic Stem Cell Transplantation for Philadelphia Chromosome–Positive Acute Myeloid Leukemia
Vijaya Raj Bhatt, Mojtaba Akhtari, R. Gregory Bociek, Jennifer N. Sanmann, Ji Yuan, Bhavana J. Dave, Warren G. Sanger, Anne Kessinger, and James O. Armitage
distinguish between the entities. 4 Clinical characteristics might also be helpful in making the distinction, including no history of CML or myeloproliferative disorder, no evidence of chronic or accelerated phases of CML after induction therapy, and no
Outcomes of a Dietary Intervention to Reduce Bladder Cancer Recurrence and Progression in Survivors of Non–Muscle-Invasive Bladder Cancer
Karen H. Kim Yeary, Han Yu, Margaret Gates Kuliszewski, Qiang Li, Susan E. McCann, Rachel Pratt, Frances G. Saad-Harfouche, Zinian Wang, Nikia Clark, Chong Wang, Elizabeth DiCarlo, and Li Tang
(NMIBC). NMIBC can be removed; however, up to 50% to 80% of NMIBC recurs within 5 years, with some patients experiencing progression to muscle-invasive disease with poor survival. 3 – 5 Depending on pathologic characteristics, patients with high
How to Choose An Appropriate Anticoagulant for Cancer-Associated Thrombosis
Jordan K. Schaefer, Amro Elshoury, Victoria R. Nachar, Michael B. Streiff, and Ming Y. Lim
General Anticoagulant Characteristics Anticoagulants recommended in current CAT treatment guidelines include low-molecular-weight heparin (LMWH), warfarin, and in recent years, the direct oral anticoagulants (DOACs). 4 Fondaparinux is also occasionally
Compliance With NCCN Guidelines for Evaluation and Treatment of Anemia Among Patients With Solid Tumors
Demetra Hypatia Hufnagel, Lia Manfredi Bos, Alaina Johnson Brown, and Lauren Shore Prescott
Characteristics A total of 25,018 patients met the inclusion criteria ( Table 1 ). Median age at diagnosis was 60 years (IQR, 51–68 years), and most patients were White (88%) and of non-Hispanic ethnicity (95%). The most common malignancies were respiratory tract
Systemic Therapy for Advanced Appendiceal Adenocarcinoma: An Analysis From the NCCN Oncology Outcomes Database for Colorectal Cancer
Mohamedtaki A. Tejani, Anna ter Veer, Dana Milne, Rebecca Ottesen, Tanios Bekaii-Saab, Al B. Benson III, Deborah Schrag, Stephen Shibata, John Skibber, Martin Weiser, Neal Wilkinson, and Steven J. Cohen
. All data used in this study, including patient and treatment characteristics, were longitudinally abstracted from medical records by trained data managers at each of the 8 participating Member Institutions. Eligibility for the Outcomes Database for CRC
Treatment Trends and Clinical Outcomes of Left-Sided RAS/RAF Wild-Type Metastatic Colorectal Cancer in the United States
Christopher Nevala-Plagemann, Siddharth Iyengar, Andrew D. Trunk, Lisa Pappas, Benjamin Haaland, and Ignacio Garrido-Laguna
Guidelines; Version 2.2021) do not specify a preferred chemotherapy plus targeted therapy combination for the up-front management of fit patients with left-sided RAS/RAF WT mCRC. 10 Clearly there is a need to identify patient or tumor characteristics that
