. Pathology showed a grade 3 invasive ductal carcinoma of the right breast. Hormonal studies showed a tumor staining positive for estrogen receptors (70%) and progesterone receptors (80%). Her-2/neu was negative at 0%. Ki-67 was 60%. Axillary lymph node biopsy
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Lauren Nye, Timothy K. Huyck, and William J. Gradishar
James M. Cleary, Scott Rodig, Paul M. Barr, Atul B. Shinagare, Jeffrey W. Clark, Geoffrey I. Shapiro, and Philippe Armand
presented with lymphadenopathy and right arm edema. Pathology revealed anaplastic large cell lymphoma. Immunohistochemistry was positive for ALK1 and fluorescence in situ hybridization analysis demonstrated a t(2;5) chromosomal translocation. The patient
Stephen B. Edge
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Philip E. Castle
-diagnosed cervical intraepithelial neoplasia grade 2 to the quality control pathology-reviewed diagnoses: an ALTS report . Am J Clin Pathol 2007 ; 127 : 805 – 815 . 79. Stoler MH Castle PE Solomon D Schiffman M . The expanded use of HPV testing in
Paul F. Engstrom, Juan Pablo Arnoletti, Al B. Benson III, Jordan D. Berlin, J. Michael Berry, Yi-Jen Chen, Michael A. Choti, Harry S. Cooper, Raza A. Dilawari, Dayna S. Early, Peter C. Enzinger, Marwan G. Fakih, James Fleshman Jr., Charles Fuchs, Jean L. Grem, James A. Knol, Lucille A. Leong, Edward Lin, Mary F. Mulcahy, Eric Rohren, David P. Ryan, Leonard Saltz, David Shibata, John M. Skibber, William Small Jr., Constantinos Sofocleous, James Thomas, Alan P. Venook, and Christopher Willett
persistent infection with a high-risk form of HPV (e.g., HPV-16 or -18) is believed to be strongest. 4 , 6 , 7 For example, a study of tumor specimens from 60 pathology laboratories showed that HPV-16 was detected in 84% and 0% of anal and rectal cancer
Frank Qian Zhan, Vathani Sharon Packianathan, and Nathalie Charlotte Zeitouni
Merkel cell carcinoma-a case showing replacement of tumour cells by foamy cells . Br J Dermatol 2000 ; 142 : 1184 – 1189 . 25 Weedon D . Skin Pathology . 2nd ed . New York : Churchill Livingstone ; 2002 : 989 – 991 . 26
Lin-Chi Chen, William D. Travis, and Lee M. Krug
proposed criteria for large-cell neuroendocrine carcinoma. An ultrastructural, immunohistochemical, and flow cytometric study of 35 cases . Am J Surg Pathol 1991 ; 15 : 529 – 553 . 4. Travis WD Brambilla E Muller-Hermelink HK . Pathology and
Lucas Vieira dos Santos, João Paulo Lima, Kathia Cristina Abdalla, Arinilda Campos Bragagnoli, Florinda Almeida Santos, Alexandre dos Anjos Jácome, and Fabiano Elias Porto
-hematological toxicity during treatment with imatinib in patients with early and late chronic phase chronic myeloid leukemia . Leuk Lymphoma 2008 ; 49 : 2328 – 2332 . 11. Miettinen M Lasota J . Gastrointestinal stromal tumors: pathology and prognosis at
Hyung L. Kim, Marvin R. Puymon, Maochun Qin, Khurshid Guru, and James L. Mohler
products discussed in the article or their competitors. References 1. Jemal A Siegel R Ward E . Cancer statistics, 2008 . CA Cancer J Clin 2008 ; 58 : 71 – 96 . 2. Yatani R Chigusa I Akazaki K . Geographic pathology of latent
Paul F. Engstrom, Mara G. Bloom, George Daniel Demetri, Phillip G. Febbo, William Goeckeler, Marc Ladanyi, Bryan Loy, Kate Murphy, Michael Nerenberg, Paul Papagni, Mark Robson, Robert W. Sweetman, Sean Tunis, Jessica DeMartino, and Jonathan K. Larsen
Editorial Panel Molecular Pathology Codification Workgroup (MPCW). This group has “proposed codes which address greater than 90% of medically useful molecular testing currently being performed and within the realm of the workgroup's charge. The services
