. Pathology showed a grade 3 invasive ductal carcinoma of the right breast. Hormonal studies showed a tumor staining positive for estrogen receptors (70%) and progesterone receptors (80%). Her-2/neu was negative at 0%. Ki-67 was 60%. Axillary lymph node biopsy
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Lauren Nye, Timothy K. Huyck, and William J. Gradishar
Paul F. Engstrom, Mara G. Bloom, George Daniel Demetri, Phillip G. Febbo, William Goeckeler, Marc Ladanyi, Bryan Loy, Kate Murphy, Michael Nerenberg, Paul Papagni, Mark Robson, Robert W. Sweetman, Sean Tunis, Jessica DeMartino, and Jonathan K. Larsen
Editorial Panel Molecular Pathology Codification Workgroup (MPCW). This group has “proposed codes which address greater than 90% of medically useful molecular testing currently being performed and within the realm of the workgroup's charge. The services
Lin-Chi Chen, William D. Travis, and Lee M. Krug
proposed criteria for large-cell neuroendocrine carcinoma. An ultrastructural, immunohistochemical, and flow cytometric study of 35 cases . Am J Surg Pathol 1991 ; 15 : 529 – 553 . 4. Travis WD Brambilla E Muller-Hermelink HK . Pathology and
Francisco Civantos
lesions.) Based on pathology, 49% (n = 22) had squamous cell carcinoma, 29% (n = 13) had severe dysplasia, 20% (n = 9) had carcinoma in situ, and 2% (n = 1) had a verrucous carcinoma. The photosensitizing agent, porfimer sodium (Photofrin), was injected
Frank C. Detterbeck
been active in many ITMIG committees and workgroups. This community spans all continents (except Antarctica), and includes all specialties active in this space (thoracic surgery, radiation oncology, medical oncology, pathology, neurology, epidemiology
Julie Teruya-Feldstein
The author has no financial interest, arrangement, or affiliation with the manufacturers of any products discussed in the article or their competitors. References 1 . Jaffe E Harris N Stein H Vardiman J . Pathology and
Lucas Vieira dos Santos, João Paulo Lima, Kathia Cristina Abdalla, Arinilda Campos Bragagnoli, Florinda Almeida Santos, Alexandre dos Anjos Jácome, and Fabiano Elias Porto
-hematological toxicity during treatment with imatinib in patients with early and late chronic phase chronic myeloid leukemia . Leuk Lymphoma 2008 ; 49 : 2328 – 2332 . 11. Miettinen M Lasota J . Gastrointestinal stromal tumors: pathology and prognosis at
Justin Lee, Jennifer Axilbund, W. Brian Dalton, Daniel Laheru, Stanley Watkins, David Chu, Karen Cravero, Berry Button, Kelly Kyker-Snowman, Ian Waters, Christopher D. Gocke, Josh Lauring, and Ben Ho Park
circumferential mass around the duodenum. She underwent a pancreaticoduodenectomy (Whipple) procedure, with pathology showing a 3.0-cm moderately to poorly differentiated duodenal adenocarcinoma. Of 28 lymph nodes, 6 were positive for disease. The patient
Robert W. Carlson, D. Craig Allred, Benjamin O. Anderson, Harold J. Burstein, W. Bradford Carter, Stephen B. Edge, John K. Erban, William B. Farrar, Andres Forero, Sharon Hermes Giordano, Lori J. Goldstein, William J. Gradishar, Daniel F. Hayes, Clifford A. Hudis, Britt-Marie Ljung, David A. Mankoff, P. Kelly Marcom, Ingrid A. Mayer, Beryl McCormick, Lori J. Pierce, Elizabeth C. Reed, Jasgit Sachdev, Mary Lou Smith, George Somlo, John H. Ward, Antonio C. Wolff, and Richard Zellars
available online and not published in this issue are sections of the guidelines on noninvasive breast cancer and special considerations in breast cancer. Pathology Assessment A central component of the treatment of breast cancer is full knowledge of
Paul F. Engstrom, Juan Pablo Arnoletti, Al B. Benson III, Jordan D. Berlin, J. Michael Berry, Yi-Jen Chen, Michael A. Choti, Harry S. Cooper, Raza A. Dilawari, Dayna S. Early, Peter C. Enzinger, Marwan G. Fakih, James Fleshman Jr., Charles Fuchs, Jean L. Grem, James A. Knol, Lucille A. Leong, Edward Lin, Mary F. Mulcahy, Eric Rohren, David P. Ryan, Leonard Saltz, David Shibata, John M. Skibber, William Small Jr., Constantinos Sofocleous, James Thomas, Alan P. Venook, and Christopher Willett
persistent infection with a high-risk form of HPV (e.g., HPV-16 or -18) is believed to be strongest. 4 , 6 , 7 For example, a study of tumor specimens from 60 pathology laboratories showed that HPV-16 was detected in 84% and 0% of anal and rectal cancer
