, which should be clarified on the pathology report. Immunohistochemical markers CK20 and CD56 tend to be positive in most cases of MCC, and neuroendocrine markers such as chromogranin, neuron-specific enolase, and synaptophysin may be present as well, he
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Andy I. Chen and Ranjana H. Advani
Edited by Kerrin G. Robinson
Disclosure: Désirée Lie, MD, MSEd, has disclosed no relevant financial relationships. References 1. Jaffe ES Harris NL Stein H Vardiman JW . World Health Organization Classification of Tumours: Pathology and Genetics of Tumours of the
Frank Qian Zhan, Vathani Sharon Packianathan, and Nathalie Charlotte Zeitouni
Merkel cell carcinoma-a case showing replacement of tumour cells by foamy cells . Br J Dermatol 2000 ; 142 : 1184 – 1189 . 25 Weedon D . Skin Pathology . 2nd ed . New York : Churchill Livingstone ; 2002 : 989 – 991 . 26
Julie Teruya-Feldstein
The author has no financial interest, arrangement, or affiliation with the manufacturers of any products discussed in the article or their competitors. References 1 . Jaffe E Harris N Stein H Vardiman J . Pathology and
Lauren Nye, Timothy K. Huyck, and William J. Gradishar
. Pathology showed a grade 3 invasive ductal carcinoma of the right breast. Hormonal studies showed a tumor staining positive for estrogen receptors (70%) and progesterone receptors (80%). Her-2/neu was negative at 0%. Ki-67 was 60%. Axillary lymph node biopsy
Yong Li, Xian Chen, Yanchun Qu, Jia-Ming Fan, Yan Li, Hui Peng, Yaojie Zheng, Yihong Zhang, and Hai-Bo Zhang
.1097/PAS.0000000000000404 25723109 11. Jo VY , Fletcher CD . WHO classification of soft tissue tumours: an update based on the 2013 (4th) edition . Pathology 2014 ; 46 : 95 – 104 . 24378391 10.1097/PAT.0000000000000050 12. Robinson DR , Wu YM
Kazuki Sudo, Xuemei Wang, Lianchun Xiao, Roopma Wadhwa, Hironori Shiozaki, Elena Elimova, David C. Rice, Jeffrey H. Lee, Brian Weston, Manoop S. Bhutani, Adarsh Hiremath, Nikolaos Charalampakis, Ritsuko Komaki, Mariela A. Blum, Stephen G. Swisher, Dipen M. Maru, Heath D. Skinner, Jeana L. Garris, Jane E. Rogers, Wayne L. Hofstetter, and Jaffer A. Ajani
, Houston, TX, USA. References 1. Taketa T Sudo K Correa AM . Post chemoradiation surgical pathology stage can customize the surveillance strategy in patients with esophageal adenocarcinoma . J Natl Compr Canc Netw 2014 ; 12 : 1139 – 1144
Robert W. Carlson, D. Craig Allred, Benjamin O. Anderson, Harold J. Burstein, W. Bradford Carter, Stephen B. Edge, John K. Erban, William B. Farrar, Andres Forero, Sharon Hermes Giordano, Lori J. Goldstein, William J. Gradishar, Daniel F. Hayes, Clifford A. Hudis, Britt-Marie Ljung, David A. Mankoff, P. Kelly Marcom, Ingrid A. Mayer, Beryl McCormick, Lori J. Pierce, Elizabeth C. Reed, Jasgit Sachdev, Mary Lou Smith, George Somlo, John H. Ward, Antonio C. Wolff, and Richard Zellars
available online and not published in this issue are sections of the guidelines on noninvasive breast cancer and special considerations in breast cancer. Pathology Assessment A central component of the treatment of breast cancer is full knowledge of
James M. Cleary, Scott Rodig, Paul M. Barr, Atul B. Shinagare, Jeffrey W. Clark, Geoffrey I. Shapiro, and Philippe Armand
presented with lymphadenopathy and right arm edema. Pathology revealed anaplastic large cell lymphoma. Immunohistochemistry was positive for ALK1 and fluorescence in situ hybridization analysis demonstrated a t(2;5) chromosomal translocation. The patient
Paul F. Engstrom, Mara G. Bloom, George Daniel Demetri, Phillip G. Febbo, William Goeckeler, Marc Ladanyi, Bryan Loy, Kate Murphy, Michael Nerenberg, Paul Papagni, Mark Robson, Robert W. Sweetman, Sean Tunis, Jessica DeMartino, and Jonathan K. Larsen
Editorial Panel Molecular Pathology Codification Workgroup (MPCW). This group has “proposed codes which address greater than 90% of medically useful molecular testing currently being performed and within the realm of the workgroup's charge. The services
