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Presenter: Stephen W. Behrman

intervention and investigation. High-quality imaging with either CT or MRI is recommended, and patients should undergo genetic evaluation to assess for germline somatic alterations. Prognosis According to Dr. Behrman, perception among the public and

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Guidelines recommend starting screening earlier and often include breast MRI in addition to mammography.” The NCCN Guidelines for Patients: Breast Cancer Screening and Diagnosis also address the appropriate evaluation of breast symptoms most commonly seen

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Ammar Sukari, Misako Nagasaka, and Erin Wakeling

. The right lung sample was positive for EGFR exon 18 mutation (G719R) and T790M. The left lung sample showed EGFR exon 19 deletion (E746 del) and T790M. At diagnosis, she did not have any metastases outside the thoracic area and her brain MRI at

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Robert J. Besaw, Adrienne R. Terra, Grace L. Malvar, Tobias R. Chapman, Lauren M. Hertan, and Benjamin L. Schlechter

and her anemia normalized within 5 months. During cycle 6, the patient developed headaches and auditory hallucinations. A brain MRI scan revealed a 3.3 × 3.0-cm right posterior temporal mass of unknown age because no prior brain imaging had been

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Hugo J.A. Adams, John M.H. de Klerk, Rob Fijnheer, Stefan V. Dubois, Rutger A.J. Nievelstein, and Thomas C. Kwee

pretreatment imaging of DLBCL (whether diagnostic CT alone, FDG-PET/CT, MRI, or FDG-PET/MRI) is under continuing development, and surely goes beyond mere integration into the existing NCCN-IPI. Factors such as cost-effectiveness and the ability of pretreatment

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Mary B. Daly, Jennifer E. Axilbund, Saundra Buys, Beth Crawford, Carolyn D. Farrell, Susan Friedman, Judy E. Garber, Salil Goorha, Stephen B. Gruber, Heather Hampel, Virginia Kaklamani, Wendy Kohlmann, Allison Kurian, Jennifer Litton, P. Kelly Marcom, Robert Nussbaum, Kenneth Offit, Tuya Pal, Boris Pasche, Robert Pilarski, Gwen Reiser, Kristen Mahoney Shannon, Jeffrey R. Smith, Elizabeth Swisher, and Jeffrey N. Weitzel

breast cancer. For example, this risk threshold was used in a recent update to the American Cancer Society (ACS) guidelines on breast screening that incorporates MRI. 124 First-degree relatives of individuals with a known deleterious gene mutation in

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Barbara Dull, Andrew Linkugel, Julie A. Margenthaler, and Amy E. Cyr

%. 1 In this group of patients, the NCCN Clinical Practice Guidelines in Oncology (NCCN Guidelines) recommend standard imaging with diagnostic bilateral mammography and ultrasound; breast MRI may also be used. 3 Additional staging studies are only

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Benjamin E. Greer, Wui-Jin Koh, Nadeem R. Abu-Rustum, Sachin M. Apte, Susana M. Campos, John Chan, Kathleen R. Cho, Larry Copeland, Marta Ann Crispens, Nefertiti DuPont, Patricia J. Eifel, David K. Gaffney, Warner K. Huh, Daniel S. Kapp, John R. Lurain III, Lainie Martin, Mark A. Morgan, Robert J. Morgan Jr., David Mutch, Steven W. Remmenga, R. Kevin Reynolds, William Small Jr., Nelson Teng, and Fidel A. Valea

, cystoscopy, and proctosigmoidoscopy. More complex radiologic and surgical staging procedures are not addressed in the FIGO classification. In the United States, however, CT, MRI, combined PET-CT, and surgical staging are often used to guide treatment options

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Ritesh R. Kotecha, Ronan Flippot, Taylor Nortman, Annalisa Guida, Sujata Patil, Bernard Escudier, Robert J. Motzer, Laurence Albiges, and Martin H. Voss

Cancer Center for patients with mRCC included mandatory brain screening by CT/MRI at study entry. Among 1,689 patients screened, 72 (4.3%; 95% CI, 3.3%–5.3%) were found to have incidental brain metastases without documented neurologic symptoms upon

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Randy C. Miles, Christoph I. Lee, Qin Sun, Aasthaa Bansal, Gary H. Lyman, Jennifer M. Specht, Catherine R. Fedorenko, Mikael Anne Greenwood-Hickman, Scott D. Ramsey, and Janie M. Lee

definitions of advanced imaging surveillance. 19 – 23 Panageas et al, 23 for example, who showed advanced imaging surveillance use in 40% of early-stage breast cancer survivors using SEER-Medicare linked data, included breast MRI in their analysis, likely