% CI, 2%–16%). 26 This model was validated in an independent dataset. 28 Surgical Options for Patients With Relapsed or Stage IV Disease Patients with stage IV disease also may benefit from surgery. For example, lymph nodes suspicious for
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Kidney Cancer, Version 3.2022, NCCN Clinical Practice Guidelines in Oncology
Robert J. Motzer, Eric Jonasch, Neeraj Agarwal, Ajjai Alva, Michael Baine, Kathryn Beckermann, Maria I. Carlo, Toni K. Choueiri, Brian A. Costello, Ithaar H. Derweesh, Arpita Desai, Yasser Ged, Saby George, John L. Gore, Naomi Haas, Steven L. Hancock, Payal Kapur, Christos Kyriakopoulos, Elaine T. Lam, Primo N. Lara, Clayton Lau, Bryan Lewis, David C. Madoff, Brandon Manley, M. Dror Michaelson, Amir Mortazavi, Lakshminarayanan Nandagopal, Elizabeth R. Plimack, Lee Ponsky, Sundhar Ramalingam, Brian Shuch, Zachary L. Smith, Jeffrey Sosman, Mary A. Dwyer, Lisa A. Gurski, and Angela Motter
Older Patients, Cognitive Impairment, and Cancer: An Increasingly Frequent Triad
Martine Extermann
. 13 Marcantonio ER Goldman L Mangione CM . A clinical prediction rule for delirium after elective noncardiac surgery . JAMA 1994 ; 271 : 134 – 139 . 14 Inouye SK Viscoli CM Horwitz RI . A predictive model for delirium in
Hepatobiliary Cancers, Version 2.2021, NCCN Clinical Practice Guidelines in Oncology
Al B. Benson, Michael I. D’Angelica, Daniel E. Abbott, Daniel A. Anaya, Robert Anders, Chandrakanth Are, Melinda Bachini, Mitesh Borad, Daniel Brown, Adam Burgoyne, Prabhleen Chahal, Daniel T. Chang, Jordan Cloyd, Anne M. Covey, Evan S. Glazer, Lipika Goyal, William G. Hawkins, Renuka Iyer, Rojymon Jacob, R. Kate Kelley, Robin Kim, Matthew Levine, Manisha Palta, James O. Park, Steven Raman, Sanjay Reddy, Vaibhav Sahai, Tracey Schefter, Gagandeep Singh, Stacey Stein, Jean-Nicolas Vauthey, Alan P. Venook, Adam Yopp, Nicole R. McMillian, Cindy Hochstetler, and Susan D. Darlow
this disease, patients need careful consideration of treatment choice given the risk of potential toxicities from treatment and potential benefits. Surgery Partial hepatectomy is a potentially curative therapy for patients with a solitary tumor of
Systemic Therapy for Metastatic Melanoma in 2012: Dawn of a New Era
Shailender Bhatia and John A. Thompson
as surgery or radiation therapy, may provide palliation of symptoms caused by local tumor growth, the cornerstone of treatment for metastatic melanoma is systemic therapy to address the clinical and subclinical sites of metastases. Chemotherapeutic
A Case of Diffuse Large B-Cell Lymphoma in Association With Paraesophageal Leiomyoma: Highlighting False-Positivity of PET Scan and Importance of Tissue Diagnosis
Rajinder S. Grover, Kemp Kernstine, and Amrita Krishnan
performance status, and quick wound healing, which allowed her to receive chemotherapy within 4 weeks of the esophageal surgery. In an alternate scenario, if this patient had only undergone superficial parotidectomy, she would have been treated as stage IV
Gastric and Esophageal Cancers: Guidelines Updates
Presented by: Crystal S. Denlinger, Kristina A. Matkowskyj, and Mary F. Mulcahy
newly diagnosed patients, postoperative therapy with nivolumab after preoperative chemoradiation and surgery in patients who have achieved R0 resections but have residual disease is a category 1 recommendation. For the first-line treatment of advanced
Modification and Implementation of NCCN Guidelines™ on Non–Small Cell Lung Cancer in the Middle East and North Africa Region
Abdul-Rahman Jazieh, Hanaa Bamefleh, Ahmet Demirkazik, Rabab Mohamed Gaafar, Fady B. Geara, Mansur Javaid, Jamal Khader, Kian Khodadad, Walid Omar, Ahmed Saadeddin, Hassan Al Sabe, Mohammad Behgam Shadmehr, Amgad El Sherif, Najam Uddin, Mohammad Jahanzeb, and David Ettinger
formed. The committee comprises various experts in thoracic oncology, including medical and clinical oncology, radiation oncology, pulmonology medicine, thoracic surgery, radiology, and pathology. The committee convened twice and corresponded frequently
Institutional Review of Compliance With NCCN Guidelines for Breast Cancer: Lessons Learned From Real-Time Multidimensional Synoptic Reporting
Titilayo O. Adegboyega, Jeffrey Landercasper, Jared H. Linebarger, Jeanne M. Johnson, Jeremiah J. Andersen, Leah L. Dietrich, Collin D. Driscoll, Meghana Raghavendra, Anusha R. Madadi, Mohammed Al-Hamadani, Choua A. Vang, Kristen A. Marcou, Jane Hudak, and Ronald S. Go
emphasizing the importance of NCCN Guidelines. Since 2009, NCCN Guideline compliance has been recorded by surgeons prospectively at the point of patient contact before and after surgery using electronic synoptic templates (EST). The EST is incorporated into
Nanotechnologies in Cancer Treatment and Diagnosis
Stephanie A. Morris, Dorothy Farrell, and Piotr Grodzinski
detect and diagnose early-stage cancers, identify metastases noninvasively, and guide tumor removal during surgery. For image-guided surgery, the use of targeted nanoparticles to identify lesions has been an active area of investigation. In general
Treating Elderly Patients With Muscle-Invasive Bladder Cancer
Elizabeth R. Kessler, Janet B. Kukreja, Christopher L. Geiger, and Stacy M. Fischer
validated tools ( Table 1 ). Multiple studies have found that the CGA is more sensitive than performance status in determining functional impairment and risks associated with chemotherapy or surgery. 5 The CGA can uncover age-related issues in up to 50% of
