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Leslie A. Fecher, Shrinivas Bishu, Robert J. Fontana, Salim S. Hayek, and Bryan J. Schneider

, nutritional supplements, or other potential hepatotoxins); serologic testing for viral hepatitis, muscle injury, or alcohol; and contrast-enhanced CT or MRI imaging of the liver in select patients ( Figure 3 ). Grade 3/4 liver injury occurs in 1% to 3% of

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J. Sybil Biermann, Warren Chow, Damon R. Reed, David Lucas, Douglas R. Adkins, Mark Agulnik, Robert S. Benjamin, Brian Brigman, G. Thomas Budd, William T. Curry, Aarati Didwania, Nicola Fabbri, Francis J. Hornicek, Joseph B. Kuechle, Dieter Lindskog, Joel Mayerson, Sean V. McGarry, Lynn Million, Carol D. Morris, Sujana Movva, Richard J. O'Donnell, R. Lor Randall, Peter Rose, Victor M. Santana, Robert L. Satcher, Herbert Schwartz, Herrick J. Siegel, Katherine Thornton, Victor Villalobos, Mary Anne Bergman, and Jillian L. Scavone

. Fertility consultation should also be considered. In the 2017 update, imaging of the primary site was clarified to include MRI with or without CT, both with contrast. Other imaging recommendations include chest CT and whole-body PET/CT and/or bone scan

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J. Sybil Biermann, Douglas R. Adkins, Robert S. Benjamin, Brian Brigman, Warren Chow, Ernest U. Conrad III, Deborah A. Frassica, Frank J. Frassica, Suzanne George, Kenneth R. Hande, Francis J. Hornicek, G. Douglas Letson, Joel Mayerson, Sean V. McGarry, Brian McGrath, Carol D. Morris, Richard J. O'Donnell, R. Lor Randall, Victor M. Santana, Robert L. Satcher, Herrick J. Siegel, Neeta Somaiah, and Alan W. Yasko

. Standard staging workup for a suspected primary bone sarcoma should include chest imaging (chest radiograph or CT to detect pulmonary metastases), appropriate imaging of the primary site (plain radiographs, MRI for local staging, and/or CT scan), and bone

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Presenter: Stephen W. Behrman

intervention and investigation. High-quality imaging with either CT or MRI is recommended, and patients should undergo genetic evaluation to assess for germline somatic alterations. Prognosis According to Dr. Behrman, perception among the public and

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Andrea K. Ng and Lois B. Travis

with HL who undergo radiotherapy in the modern treatment era will probably incur a lower risk for breast cancer. For survivors of HL, NCCN recommends mammogram/breast MRI screening 8 to 10 years after irradiation or by 40 years of age. The American

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Timothy Gilligan, Daniel W. Lin, Rahul Aggarwal, David Chism, Nicholas Cost, Ithaar H. Derweesh, Hamid Emamekhoo, Darren R. Feldman, Daniel M. Geynisman, Steven L. Hancock, Chad LaGrange, Ellis G. Levine, Thomas Longo, Will Lowrance, Bradley McGregor, Paul Monk, Joel Picus, Phillip Pierorazio, Soroush Rais-Bahrami, Philip Saylor, Kanishka Sircar, David C. Smith, Katherine Tzou, Daniel Vaena, David Vaughn, Kosj Yamoah, Jonathan Yamzon, Alyse Johnson-Chilla, Jennifer Keller, and Lenora A. Pluchino

experienced in the management of these patients should also be considered. Additionally, patients with postorchiectomy beta-hCG levels >5,000 IU/L should undergo brain MRI because they are at an increased risk of having brain metastases. Further workup should

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William J. Gradishar, Benjamin O. Anderson, Sarah L. Blair, Harold J. Burstein, Amy Cyr, Anthony D. Elias, William B. Farrar, Andres Forero, Sharon Hermes Giordano, Lori J. Goldstein, Daniel F. Hayes, Clifford A. Hudis, Steven J. Isakoff, Britt-Marie E. Ljung, P. Kelly Marcom, Ingrid A. Mayer, Beryl McCormick, Robert S. Miller, Mark Pegram, Lori J. Pierce, Elizabeth C. Reed, Kilian E. Salerno, Lee S. Schwartzberg, Mary Lou Smith, Hatem Soliman, George Somlo, John H. Ward, Antonio C. Wolff, Richard Zellars, Dorothy A. Shead, and Rashmi Kumar

: Breast and Ovarian (to view the most recent version of these guidelines, visit NCCN.org ). Use of MRI during initial workup is optional and may be specially considered for mammographically occult tumors. MRI may be used to define the extent of cancer

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Robert J. Motzer, Neeraj Agarwal, Clair Beard, Graeme B. Bolger, Barry Boston, Michael A. Carducci, Toni K. Choueiri, Robert A. Figlin, Mayer Fishman, Steven L. Hancock, Gary R. Hudes, Eric Jonasch, Anne Kessinger, Timothy M. Kuzel, Paul H. Lange, Ellis G. Levine, Kim A. Margolin, M. Dror Michaelson, Thomas Olencki, Roberto Pili, Bruce G. Redman, Cary N. Robertson, Lawrence H. Schwartz, Joel Sheinfeld, and Jue Wang

imaging in the diagnosis and staging of renal and perirenal neoplasms . Radiology 1985 ; 154 : 709 – 715 . 7 Janus CL Mendelson DS . Comparison of MRI and CT for study of renal and perirenal masses . Crit Rev Diag Imaging 1991 ; 32 : 69

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clinical decision-making around the use of imaging in patients with cancer by outlining all imaging procedures recommended in the NCCN Guidelines, including radiographs, CT scans, MRI, functional nuclear medicine imaging (PET, SPECT), and ultrasound. NCCN

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Barbara Dull, Andrew Linkugel, Julie A. Margenthaler, and Amy E. Cyr

%. 1 In this group of patients, the NCCN Clinical Practice Guidelines in Oncology (NCCN Guidelines) recommend standard imaging with diagnostic bilateral mammography and ultrasound; breast MRI may also be used. 3 Additional staging studies are only