, because high tumor vascularity was associated with lower locoregional control and overall survival. Contrast-enhanced dynamic MRI (CD-MRI) is an imaging modality that can be used to measure vessel permeability, tumor cellular volume, and vascular volume
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Christopher K. Bichakjian, Thomas Olencki, Murad Alam, James S. Andersen, Daniel Berg, Glen M. Bowen, Richard T. Cheney, Gregory A. Daniels, L. Frank Glass, Roy C. Grekin, Kenneth Grossman, Alan L. Ho, Karl D. Lewis, Daniel D. Lydiatt, William H. Morrison, Kishwer S. Nehal, Kelly C. Nelson, Paul Nghiem, Clifford S. Perlis, Ashok R. Shaha, Wade L. Thorstad, Malika Tuli, Marshall M. Urist, Timothy S. Wang, Andrew E. Werchniak, Sandra L. Wong, John A. Zic, Karin G. Hoffmann, Nicole R. McMillian, and Maria Ho
metastatic potential of this tumor. PET/CT scanning is gaining importance in diagnostic imaging of MCC and may be preferred in some instances. CT or MRI may be used if PET/CT is not available. In a review of 102 patients, PET/CT changed the stage and
Christopher Loiselle and Wui-Jin Koh
alter the arrangement of surrounding normal tissues. Tumor regression during treatment is a fortunate, though complex, reality and renders target definition based on a single preradiation CT scan less dependable. Serial MRI has been used to
Keli Turner, Sheelu Varghese, and H. Richard Alexander
CT scans and tissue biopsy with appropriate immunohistochemical staining. Although CT scan is the diagnostic imaging most commonly used, MRI using specific acquisition protocols may be increasingly used in the future. 20 The role of PET or PET/CT is
Ali Mokdad, Travis Browning, John C. Mansour, Hao Zhu, Amit G. Singal, and Adam C. Yopp
on characteristic radiographic imaging on dynamic contrasted-enhanced CT or MRI. Most of these diagnostic imaging studies are ordered by primary care physicians, who are at the beginning of the cancer care continuum and must not only discern an
Marta Penas-Prado, Terri S. Armstrong, and Mark R. Gilbert
. Some of these barriers can be overcome by using telehealth resources to discuss patient management across local and specialized centers. Incorporate MRI Standards and Criteria for Progression The current NCCN Guidelines do not provide specific
Aatur D. Singhi, Siraj M. Ali, Jill Lacy, Andrew Hendifar, Khanh Nguyen, Jamie Koo, Jon H. Chung, Joel Greenbowe, Jeffrey S. Ross, Marina N. Nikiforova, Herbert J. Zeh, Inderpal S. Sarkaria, Anil Dasyam, and Nathan Bahary
cycles with subsequent chemotoxicity. The patient was switched to gemcitabine and nab-paclitaxel, but again experienced chemotoxicity, and progression of her liver metastases was seen on MRI. CGP of one of her metastases revealed an exon 6 EML4 –exon 20
George D. Demetri, Scott Antonia, Robert S. Benjamin, Marilyn M. Bui, Ephraim S. Casper, Ernest U. Conrad III, Thomas F. DeLaney, Kristen N. Ganjoo, Martin J. Heslin, Raymond J. Hutchinson, John M. Kane III, G. Douglas Letson, Sean V. McGarry, Richard J. O'Donnell, I. Benjamin Paz, John D. Pfeifer, Raphael E. Pollock, R. Lor Randall, Richard F. Riedel, Karen D. Schupak, Herbert S. Schwartz, Katherine Thornton, Margaret von Mehren, and Jeffrey Wayne
and contiguity to nearby visceral structures and neurovascular landmarks. The propensities to spread to various locations vary among the subtypes of sarcoma. Therefore, imaging should be individualized based on the subtype of sarcoma. MRI with or
Gauri R. Varadhachary
mammography and ultrasound, bilateral breast MRI is a sensitive modality to evaluate for occult primary breast carcinoma. 12 – 14 Conventional workup for neck adenopathy presenting as squamous cell carcinoma CUP includes either CT or MRI and triple endoscopy
Matthias Holdhoff, Maciej M. Mrugala, Christian Grommes, Thomas J. Kaley, Lode J. Swinnen, Carlos Perez-Heydrich, and Lakshmi Nayak
diagnosis of PCNSL requires comprehensive workup and staging. In addition to imaging of the brain and entire spine using MRI with contrast, cerebrospinal fluid analysis (CSF) and ophthalmologic examination to rule out ocular involvement are necessary. Brain
