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Charise Gleason, Ajay Nooka, and Sagar Lonial

) neurotoxicity: enhancement by protein-deficient diet . J Appl Toxicol 2004 ; 24 : 497 – 500 . 16 Lonial S Waller EK Richardson PG . Risk factors and kinetics of thrombocytopenia associated with bortezomib for relapsed, refractory multiple myeloma

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Joan How and Gabriela S. Hobbs

system used only 2 covariates: a hemoglobin (Hgb) level <10 g/dL and a WBC count <4×10 9 /L or >30×10 9 /L. 3 With the presence or absence of each variable at diagnosis, 3 risk groups were identified (low = no risk factors; intermediate = either low Hgb

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Jeffrey Crawford, Jeffrey Allen, James Armitage, Douglas W. Blayney, Spero R. Cataland, Mark L. Heaney, Sally Htoy, Susan Hudock, Dwight D. Kloth, David J. Kuter, Gary H. Lyman, Brandon McMahon, David P. Steensma, Saroj Vadhan-Raj, Peter Westervelt, and Michael Westmoreland

, including the disease type, chemotherapeutic regimen (high-dose, dose-dense, or standard-dose therapy), patient risk factors, and treatment intent. Three categories based on the intent of chemotherapy have been designated by the panel, including curative

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Anita Pudusseri and Alex C. Spyropoulos

risk factors can be considered at moderate risk. 3 – 5 The procedural bleeding risk can be classified into 2 groups: high risk (with a 2-day risk of major bleeding of 2%–4%) or low risk (with a 2-day risk of major bleeding Table 1 Clinical Risk

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Kan Wu, Xu Liu, Zhihong Liu, Yiping Lu, Xianding Wang, and Xiang Li

Based on the risk factors available in the SEER database, as well as the fact that age >55 years and node-positive status are known to decrease survival, the following 5 variables were considered as high-risk characteristics for recurrence or death

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Allan C. Halpern and Sanjay K. Mandal

identify people at high risk for cutaneous malignant melanoma . CMAJ 1992 ; 147 : 445 – 453 . 23. Tucker MA Halpern A Holly EA . Clinically recognized dysplastic nevi. A central risk factor for cutaneous melanoma . JAMA 1997 ; 277 : 1439

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Brahm H. Segal and Alison G. Freifeld

. Cytosine arabinoside as a major risk factor for Streptococcus viridans septicemia following bone marrow transplantation: a 5-year prospective study . Bone Marrow Transplant 1995 ; 16 : 565 – 570 . 9. Bochud PY Calandra T Francioli P

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Judith A. Paice

should delve deeper into potential risk factors for the abuse of pain medications, according to Dr. Paice. Current or past habits with regard to alcohol and tobacco use should be explored. Environmental and genetic exposure to substance abuse disorder in

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Christopher K. Bichakjian, Thomas Olencki, Sumaira Z. Aasi, Murad Alam, James S. Andersen, Daniel Berg, Glen M. Bowen, Richard T. Cheney, Gregory A. Daniels, L. Frank Glass, Roy C. Grekin, Kenneth Grossman, Susan A. Higgins, Alan L. Ho, Karl D. Lewis, Daniel D. Lydiatt, Kishwer S. Nehal, Paul Nghiem, Elise A. Olsen, Chrysalyne D. Schmults, Aleksandar Sekulic, Ashok R. Shaha, Wade L. Thorstad, Malika Tuli, Marshall M. Urist, Timothy S. Wang, Sandra L. Wong, John A. Zic, Karin G. Hoffmann, and Anita Engh

generally have a good prognosis due to low rates of metastasis. A number of risk factors are associated with development of BCC. The most recognized environmental carcinogen is sunlight. Evidence reveals that the relationship between sun exposure and BCC

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Aby Z. Philip

-risk (defined as having 0 risk factors), 87% for intermediate-risk (1 or 2 risk factors), and 68% for high-risk groups (3 or 4 risk factors). 6 Cytogenetic data have been reported in several series of SMZL. Chromosomal aberrations have been detected in