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Exocrine Pancreas Cancer and Thromboembolic Events: A Systematic Literature Review
Andrew S. Epstein and Eileen M. O'Reilly
Analysis of Circulating Tumor Cells in Breast Cancer
Zeynep Eroglu, Odicie Fielder, and George Somlo
Through coordinated scientific, medical, and public health advances, 5-year survival rates for breast cancer approach 90%. However, microscopic residual disease frequently results in local relapse or metastasis, leading to approximately 40
Sessile Serrated Polyps: An Important Route to Colorectal Cancer
Matthew F. Kalady
initial lesion in the serrated pathway to cancer. HPs are the most common serrated polyp and are commonly located in the distal colon and rectum. Longacre and Fenoglio-Preiser 3 first recognized a subset of hyperplastic polyps with dysplasia as a
Next-Generation Cancer Vaccine Approaches: Integrating Lessons Learned From Current Successes With Promising Biotechnologic Advances
Dung T. Le and Elizabeth M. Jaffee
patients with advanced melanoma treated with gp100 peptide vaccine plus high-dose interleukin 2 (IL-2) over those treated with IL-2 alone. 12 Importantly, the success of sipuleucel-T for prostate cancer and the predicted success of agents that block the PD
Adult Cancer Pain
Robert H. Lurie Comprehensive Cancer Center of Northwestern University
Pain is one of the most common symptoms associated with cancer and one of the symptoms patients fear most; unrelieved pain denies them comfort and greatly affects their activities, motivation, interactions with family and friends, and overall quality of life. The importance of relieving pain and availability of effective therapies make it imperative that clinicians caring for cancer patients to be adept at assessing and treating cancer pain. The National Comprehensive Cancer Network Adult Cancer Pain Clinical Practice Guidelines in Oncology acknowledge the range of complex decisions faced in caring for these patients. As a result, they provide dosing guidelines for NSAIDs, opioids, and adjuvant analgesics. They also provide specific suggestions for escalating opioid dosage, managing opioid toxicity, and when and how to proceed to other techniques to manage cancer pain.
For the most recent version of the guidelines, please visit NCCN.org
Modern Approaches to Localized Cancer of the Esophagus
Robert E. Glasgow, David H. Ilson, James A. Hayman, Hans Gerdes, Mary F. Mulcahy, and Jaffer A. Ajani
E sophageal cancer is a highly lethal disease, with approximately 16,640 new cases diagnosed and 14,500 related deaths each year in the United States. 1 Despite recent decreases in the overall incidence of cancer and cancer-related deaths in the
Establishing an Anemia Clinic for Optimal Erythropoietic-Stimulating Agent Use in Hematology-Oncology Patients
Jeffrey A. Gilreath, Daniel S. Sageser, James A. Jorgenson, and George M. Rodgers
Belle S Barrett-Lee P . The European Cancer in Anaemia Survey (ECAS): a large, multinational, prospective survey defining the prevalence, incidence, and treatment of anaemia in cancer patients . Eur J Cancer 2004 ; 40 : 2293 – 2306 . 2
QIM19-117: Reducing Diagnostic Delays: Impact of a Novel Cancer Diagnostic Service
Luke Arney, Ryan Leib, Louise Schneider, Cori Kostick, Kerry Kilbridge, Ramin Khorasani, Oreofe Odejide, and Lindsay C. Carter
Background: Although timeliness of care was one of the aims of quality improvement in the Institute of Medicine’s 2001 “Crossing the Quality Chasm” report, a significant proportion of patients with cancer still experience delays in diagnosis and
Chemotherapy Hypersensitivity Reactions in Ovarian Cancer
Matthieu Picard, Ursula A. Matulonis, and Mariana Castells
Ovarian cancer is the leading cause of death among gynecologic malignancies and ranks fifth in overall cancer-related mortality among women in the United States. 1 Chemotherapy, particularly with a taxane and platinum combination, is key to
Psychostimulants for Cancer-Related Fatigue
William Breitbart and Yesne Alici
S everal pharmacologic agents have been considered and studied for the treatment of cancer-related fatigue, including psychostimulants, antidepressants, megestrol acetate, and amantadine. 1 A recent meta-analysis of pharmacologic treatment
