Overview There are 3 main histologic types of thyroid carcinoma: differentiated (including papillary, follicular, and Hürthle), medullary, and anaplastic (aggressive undifferentiated tumor). Of 53,856 patients treated for thyroid carcinoma
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R. Michael Tuttle, Douglas W. Ball, David Byrd, Gilbert H. Daniels, Raza A. Dilawari, Gerard M. Doherty, Quan-Yang Duh, Hormoz Ehya, William B. Farrar, Robert I. Haddad, Fouad Kandeel, Richard T. Kloos, Peter Kopp, Dominick M. Lamonica, Thom R. Loree, William M. Lydiatt, Judith McCaffrey, John A. Olson Jr., Lee Parks, John A. Ridge, Jatin P. Shah, Steven I. Sherman, Cord Sturgeon, Steven G. Waguespack, Thomas N. Wang, and Lori J. Wirth
James S. Blachly, Gerard Lozanski, David M. Lucas, Michael R. Grever, Kari Kendra, and Leslie A. Andritsos
); papillary thyroid cancer (up to 69%); malignant melanoma (40%–60%); and hairy cell leukemia (HCL; up to 100% in a landmark paper). 2 – 9 Melanoma and HCL are of particular interest because both diseases have shown dramatic responses to therapy with the
Robert I Haddad, Lindsay Bischoff, Douglas Ball, Victor Bernet, Erik Blomain, Naifa Lamki Busaidy, Michael Campbell, Paxton Dickson, Quan-Yang Duh, Hormoz Ehya, Whitney S. Goldner, Theresa Guo, Megan Haymart, Shelby Holt, Jason P. Hunt, Andrei Iagaru, Fouad Kandeel, Dominick M. Lamonica, Susan Mandel, Stephanie Markovina, Bryan McIver, Christopher D. Raeburn, Rod Rezaee, John A. Ridge, Mara Y. Roth, Randall P. Scheri, Jatin P. Shah, Jennifer A. Sipos, Rebecca Sippel, Cord Sturgeon, Thomas N. Wang, Lori J. Wirth, Richard J. Wong, Michael Yeh, Carly J. Cassara, and Susan Darlow
main histologic types of thyroid carcinoma are (1) differentiated (including papillary, follicular, and Hürthle cell); (2) medullary; and (3) anaplastic, which is an aggressive undifferentiated tumor. Mortality rates for thyroid carcinoma are, in
Thai H. Ho and Eric Jonasch
renal parenchyma. Histologic classifications include clear cell, papillary, chromophobe, and translocation; rare subtypes include renal medullary and collecting duct. Hereditary familial RCC syndromes have yielded clues regarding the molecular
Nalan Nese, Ruta Gupta, Matthew H. T. Bui, and Mahul B. Amin
Edited by Kerrin G. Robinson
urothelial dysplasia . Mod Pathol 2003 ; 16 : 187 – 191 . 40 Sun W Herrera GA . E-cadherin expression in urothelial carcinoma in situ, superficial papillary transitional cell carcinoma, and invasive transitional cell carcinoma . Hum Pathol
Robert J. Motzer, Neeraj Agarwal, Clair Beard, Graeme B. Bolger, Barry Boston, Michael A. Carducci, Toni K. Choueiri, Robert A. Figlin, Mayer Fishman, Steven L. Hancock, Gary R. Hudes, Eric Jonasch, Anne Kessinger, Timothy M. Kuzel, Paul H. Lange, Ellis G. Levine, Kim A. Margolin, M. Dror Michaelson, Thomas Olencki, Roberto Pili, Bruce G. Redman, Cary N. Robertson, Lawrence H. Schwartz, Joel Sheinfeld, and Jue Wang
R. Michael Tuttle, Douglas W. Ball, David Byrd, Raza A. Dilawari, Gerard M. Doherty, Quan-Yang Duh, Hormoz Ehya, William B. Farrar, Robert I. Haddad, Fouad Kandeel, Richard T. Kloos, Peter Kopp, Dominick M. Lamonica, Thom R. Loree, William M. Lydiatt, Judith C. McCaffrey, John A. Olson Jr., Lee Parks, John A. Ridge, Jatin P. Shah, Steven I. Sherman, Cord Sturgeon, Steven G. Waguespack, Thomas N. Wang, and Lori J. Wirth
men. 7 Thyroid carcinoma has 3 main histologic types: differentiated (including papillary, follicular, and Hürthle cell), medullary, and anaplastic (aggressive undifferentiated tumor). Of 53,856 patients treated for thyroid carcinoma between 1985 and
Susan M. Domchek, Jill E. Stopfer, and Timothy R. Rebbeck
– 1479 . 5. Struewing JP Watson P Easton DF . Prophylactic oophorectomy in inherited breast/ovarian cancer families . J Natl Cancer Inst Monogr 1995 ; 17 : 33 – 35 . 6. White CD . Papillary intraperitoneal neoplasia resembling
Robert J. Motzer, Eric Jonasch, Neeraj Agarwal, Clair Beard, Sam Bhayani, Graeme B. Bolger, Sam S. Chang, Toni K. Choueiri, Ithaar H. Derweesh, Shilpa Gupta, Steven L. Hancock, Jenny J. Kim, Timothy M. Kuzel, Elaine T. Lam, Clayton Lau, Ellis G. Levine, Daniel W. Lin, Kim A. Margolin, M. Dror Michaelson, Thomas Olencki, Roberto Pili, Elizabeth R. Plimack, Edward N. Rampersaud, Bruce G. Redman, Charles J. Ryan, Joel Sheinfeld, Kanishka Sircar, Brad Somer, Jue Wang, Richard B. Wilder, Mary A. Dwyer, and Rashmi Kumar
RCC has increased by 1.7% per year for the past 10 years. 2 Approximately 90% of renal tumors are RCC, and 85% of these are clear cell tumors. 3 Other less common cell types include papillary, chromophobe, “translocation-type,” and Bellini
R. Michael Tuttle and R. Leboeuf
. References 1. Mazzaferri EL Kloos RT . Clinical review 128: current approaches to primary therapy for papillary and follicular thyroid cancer . J Clin Endocrinol Metab 2001 ; 86 : 1447 – 1463 . 2. Hundahl SA Fleming ID Fremgen AM Menck
