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Jason P. Wilson, David Mattson, and Stephen B. Edge

trial, combined with the results of the NSABP B-06 trials, changed the standard therapy from radical mastectomy to breast-conserving therapy, with axillary lymph node dissection (AND) performed for staging and local control. 2 In 1994, sentinel lymph

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Victor T.G. Lin, Lisle M. Nabell, Sharon A. Spencer, William R. Carroll, Shuko Harada, and Eddy S. Yang

below it. Dose reductions, holds, and discontinuations, and palliative radiotherapies are not shown for the sake of simplicity. Abbreviations: LND, lymph node dissection; RT, radiation therapy. for phase I clinical trials and limited

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Thomas A. D'Amico

-stage non–small cell lung cancer (NSCLC), lobectomy with mediastinal lymph node dissection is considered the optimal treatment. 2 Segmentectomy, anatomic sublobar resection of one or more bronchopulmonary segments, has a role in the management of some

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David A. Kooby and Daniel G. Coit

gastric lymphatics by using activated carbon particle (CH44) and lymph node metastasis of gastric cancer . J Jpn Surg Soc 1988 ; 89 : 664 – 670 . 22 Kodama Y Sugimachi K Soejima K . Evaluation of extensive lymph node dissection for

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Samuel W. Beenken and Marshall M. Urist

and chemotherapy in the treatment of Merkel cell carcinoma . Cancer 1997 ; 80 : 881 – 885 . 9 Victor NS Morton B Smith JW . Merkel cell cancer: is prophylactic lymph node dissection indicated? Am Surg 1996 ; 62 : 879 – 882

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Jeffrey F. Moley

thyroidectomy is the appropriate treatment for the primary tumor, accompanied by a central node dissection. Calcitonin levels are virtually always elevated in these patients. Classification and methods of central neck lymph node dissection have been described by

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Chandrakanth Are

: treatment in T1b disease, need for bile duct resection, extent of lymph node dissection, resection of port sites, treatment of jaundiced patients, and extent of hepatic resection at the NCCN 19th Annual Conference. Treatment of T1b Disease Although

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Nadeem R. Abu-Rustum

endometrial cancer was introduced by Burke et al 6 in 1996, but has only recently gained popularity. The appeal of SLN mapping lies in the possible avoidance of “overstaging” via lymph node dissection of normal/negative nodes and enhanced precision in finding

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NCCN Guidelines® Insights: Melanoma: Cutaneous, Version 2.2021

Featured Updates to the NCCN Guidelines

Susan M. Swetter, John A. Thompson, Mark R. Albertini, Christopher A. Barker, Joel Baumgartner, Genevieve Boland, Bartosz Chmielowski, Dominick DiMaio, Alison Durham, Ryan C. Fields, Martin D. Fleming, Anjela Galan, Brian Gastman, Kenneth Grossmann, Samantha Guild, Ashley Holder, Douglas Johnson, Richard W. Joseph, Giorgos Karakousis, Kari Kendra, Julie R. Lange, Ryan Lanning, Kim Margolin, Anthony J. Olszanski, Patrick A. Ott, Merrick I. Ross, April K. Salama, Rohit Sharma, Joseph Skitzki, Jeffrey Sosman, Evan Wuthrick, Nicole R. McMillian, and Anita M. Engh

surveillance (where radiologic expertise is available) without completion lymph node dissection, given lack of improved MSS in 2 RCTs assessing the merits of completion lymph node dissection following a positive SLNB vs clinical observation with nodal

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James L. Mohler

. radical prostatectomy vs. external beam radiation vs. brachytherapy) and type of treatment (need for neurovascular bundle resection and/or pelvic lymph node dissection during radical prostatectomy) for clinically localized prostate cancer or adjuvant or