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Breast Cancer Risk Reduction Therapy: The Low-Hanging Fruit

Therese B. Bevers

identify women for whom risk reduction therapy should be seriously considered. So who are these women? Women for whom the benefits of risk reduction therapy almost always outweigh the harms are those with atypical hyperplasia (AH), both ductal and lobular

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Update on PSA Testing

Mark L. Gonzalgo and H. Ballentine Carter

prostate volume improves differentiation of benign prostatic hyperplasia and organ-confined prostatic cancer . Br J Urol 1994 ; 73 : 538 – 543 . 14. Benson MC McMahon DJ Cooner WH . An algorithm for prostate cancer detection in a patient

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CLO23-029: An APP-Run Lymphadenopathy Clinic: The Cleveland Clinic Experience

Christopher D’Andrea, Stacy Mathews, and Brian Hill

/granulomatous inflammation/sarcoidosis (6 of 27, 22%), followed by followed by follicular hyperplasia (3 of 27, 11%). The most common malignant diagnosis was lymphoma (87.5% of all malignancies) with follicular lymphoma, grade 1-2 occurring most frequently (14 of 42 lymphoid

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Perspectives on Margins in DCIS: Pathology

Susan Lester

ink, the ink may leak into these clefts, making identification of the true margin difficult. Cautery and crush artifact can make it impossible to distinguish DCIS from atypical ductal hyperplasia, or even hyperplasia without atypia. Complete sampling

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Treatment Options for Merkel Cell Carcinoma

Samuel W. Beenken and Marshall M. Urist

. 10 Gould VE Moll R Moll I . Neuroendocrine (Merkel) cells of the skin: hyperplasias, dysplasias, and neoplasms . Lab Invest 1985 ; 52 : 334 – 353 . 11 Haag ML Glass LF Fenske NA . Merkel cell carcinoma. Diagnosis and treatment

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Indication and Timing of Thyroid Surgery for Patients with Hereditary Medullary Thyroid Cancer Syndromes

Jennifer B. Ogilvie and Electron Kebebew

; 85 : 919 – 922 . 12. Libbey NP Nowakowski KJ Tucci JR . C-cell hyperplasia of the thyroid in a patient with goitrous hypothyroidism and Hashimoto's thyroiditis . Am J Surg Pathol 1989 ; 13 : 71 – 77 . 13. Raue F Frank-Raue K

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Role of Complexed PSA in the Early Detection of Prostate Cancer

Yoshio Naya and Koji Okihara

hyperplasia on elevated serum prostatic specific antigen levels . J Urol 1995 ; 154 : 407 – 413 . 5 Djavan B Zlotta AR Byttebier G . Prostate specific antigen density of the transition zone for early detection of prostate cancer . J Urol 1998

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Breast Cancer Screening and Diagnosis, Version 3.2018, NCCN Clinical Practice Guidelines in Oncology

Therese B. Bevers, Mark Helvie, Ermelinda Bonaccio, Kristine E. Calhoun, Mary B. Daly, William B. Farrar, Judy E. Garber, Richard Gray, Caprice C. Greenberg, Rachel Greenup, Nora M. Hansen, Randall E. Harris, Alexandra S. Heerdt, Teresa Helsten, Linda Hodgkiss, Tamarya L. Hoyt, John G. Huff, Lisa Jacobs, Constance Dobbins Lehman, Barbara Monsees, Bethany L. Niell, Catherine C. Parker, Mark Pearlman, Liane Philpotts, Laura B. Shepardson, Mary Lou Smith, Matthew Stein, Lusine Tumyan, Cheryl Williams, Mary Anne Bergman, and Rashmi Kumar

is recommended if the diagnosis by core needle biopsy is an indeterminate lesion, a benign lesion that is not concordant with imaging, atypical ductal hyperplasia (ADH) or other specific histologies that require additional tissue, including mucin

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State-of-the-Art Workup and Initial Management of Newly Diagnosed Molar Pregnancy and Postmolar Gestational Trophoblastic Neoplasia

Kevin M. Elias, Ross S. Berkowitz, and Neil S. Horowitz

generally entirely of paternal origin. 5 CHM is associated with more generalized trophoblastic hyperplasia and hydropic swelling of the chorionic villi and is not associated with fetal or embryonic tissues. PHM is generally triploid, in which the extra set

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Prostate Biopsy Strategies: Current State of the Art

Badar M. Mian

gene status in adenosis with comparison to benign prostatic hyperplasia, prostatic intraepithelial neoplasia, and cancer . Hum Pathol 1999 ; 30 : 1077 – 1086 . 28 Bostwick DG . Prostatic intraepithelial neoplasia is a risk factor for