The NCCN Guidelines for Bone Cancer provide interdisciplinary recommendations for treating chordoma, chondrosarcoma, giant cell tumor of bone, Ewing sarcoma, and osteosarcoma. These NCCN Guidelines Insights summarize the NCCN Bone Cancer Panel's guideline recommendations for treating Ewing sarcoma. The data underlying these treatment recommendations are also discussed.
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NCCN Guidelines Insights: Bone Cancer, Version 2.2017
J. Sybil Biermann, Warren Chow, Damon R. Reed, David Lucas, Douglas R. Adkins, Mark Agulnik, Robert S. Benjamin, Brian Brigman, G. Thomas Budd, William T. Curry, Aarati Didwania, Nicola Fabbri, Francis J. Hornicek, Joseph B. Kuechle, Dieter Lindskog, Joel Mayerson, Sean V. McGarry, Lynn Million, Carol D. Morris, Sujana Movva, Richard J. O'Donnell, R. Lor Randall, Peter Rose, Victor M. Santana, Robert L. Satcher, Herbert Schwartz, Herrick J. Siegel, Katherine Thornton, Victor Villalobos, Mary Anne Bergman, and Jillian L. Scavone
Breast Cancer Risk Assessment: A Guide for Clinicians Using the NCCN Breast Cancer Risk Reduction Guidelines
Sofia D. Merajver and Kara Milliron
Breast cancer, a complex and heterogeneous disease, is the most common malignancy diagnosed in women in the United States, with over 180,000 new cases and approximately 44,000 deaths per year. Breast cancer risk is influenced by a large number of factors, including age, family history, reproductive and hormonal history, proliferative breast conditions, physical activity, diet, and environmental exposures. These factors all interact in a complex manner to contribute to the risk of developing breast cancer. Because the interactions between risk factors are poorly understood at the molecular level, it is difficult to accurately evaluate the breast cancer risk of a given person presenting with an individual constellation of factors. To better define the population at increased risk that may warrant specific intervention, several models exist to estimate a woman's risk for developing breast cancer and for harboring a germline mutation in a cancer susceptibility gene. This article summarizes these models and gives brief guidelines about which model may be preferable given a specific family history.
Discussing Colorectal Cancer
Paul F. Engstrom
QIM20-125: OBESE: Oncologist Based Emphasis on Survivor Education-Physician Driven Weight Loss Counseling and Outcomes in TNBC
Marwah W. Farooqui, Caitlin Carter, Nicholas Gustafson, Saherish Abbasi, Sravani Sagireddy, Kathryn Hockensmith, Amy Stein, Masood Ghouse, and Krishan Srinivasan
Obesity has an association with triple negative breast cancer (TNBC). Healthy diet, weight loss, and exercise have lead to favorable outcomes (overall survival [OS], progression free survival [PFS],quality of life [QOL])in TNBC. We aim to highlight
News About the Tiny Pharmacists Within Us
Margaret Tempero
My mother was sure that diet and health were intertwined. Growing up, I survived on skim milk, fruit, and vegetables. Since she had a tight budget, we also had only the leanest and cheapest meat, which regularly included beef tongue (it’s not bad
PCL22-187: Functional Role of TREM2 in NASH and HCC Development
Souradipta Ganguly, Aleman Muench German, Brin Rosenthal, Naser Khader, Asra Irfan, Nathalia Castorena, Pejman Soroosh, Tatiana Kisseleva, David A Brenner, and Debanjan Dhar
harmful or protective during NASH-HCC. METHODS : We used three different models of NASH-Fibrosis-HCC: (1) Foz/Foz mice fed with Western Diet (WD) closely mimics human NASH and NASH-HCC (Ganguly et. al. CMGH 2021). Foz/Foz and Trem2 -/-: :Foz/Foz were put
Survivorship: Nutrition and Weight Management, Version 2.2014
Crystal S. Denlinger, Jennifer A. Ligibel, Madhuri Are, K. Scott Baker, Wendy Demark-Wahnefried, Don Dizon, Debra L. Friedman, Mindy Goldman, Lee Jones, Allison King, Grace H. Ku, Elizabeth Kvale, Terry S. Langbaum, Kristin Leonardi-Warren, Mary S. McCabe, Michelle Melisko, Jose G. Montoya, Kathi Mooney, Mary Ann Morgan, Javid J. Moslehi, Tracey O’Connor, Linda Overholser, Electra D. Paskett, Jeffrey Peppercorn, Muhammad Raza, M. Alma Rodriguez, Karen L. Syrjala, Susan G. Urba, Mark T. Wakabayashi, Phyllis Zee, Nicole R. McMillian, and Deborah A. Freedman-Cass
Lifestyles: Nutrition and Weight Management Healthy lifestyle habits, such as engaging in routine physical activity, maintaining a healthy diet and weight, and avoiding tobacco use, have been associated with improved health outcomes and quality of life. For
Letter to the Editor Re: Influence of Food With Different Fat Concentrations on Alectinib Exposure: A Randomized Crossover Pharmacokinetic Trial
Andrew D. Frugé, Kristen S. Smith, Sylvia L. Crowder, and Wendy Demark-Wahnefried
authors’ pioneering efforts, given that little research has been done to explore diet–drug interactions in oncology care. Moreover, study strengths include rigor in assessing alectinib exposure, careful monitoring of adverse events, and a solid double
HSR23-088: Laparoscopic Complete Mesocolic Excision Versus Standard Laparoscopic Right Hemicolectomy in Egyptian Right Colon Cancer
W. Galal Elshazly, Mohamed Abdelhalim, Ahmed Mohammed Radwan, and Amr Samir
flatus as well as shorter time interval to liquid and normal diet after surgery. The postoperative hospital stay was significantly shorter in the SLC group. The complication rate was slightly lower in the SLC (15.5%) than in the LCME group (22.7 %). The 3
Reply To the Letter to the Editor by Frugé et al
Daan A.C. Lanser, Anne-Marie C. Dingemans, Ron H.J. Mathijssen, and G.D. Marijn Veerman
of the fat difference between the tested diets, we also did not assert this in our paper. In our discussion, we have delved into potential mechanisms for this study outcome, and the chemical properties (eg, lipophilic nature) of alectinib seemed to
