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Management of Patients With Cytogenetically Normal Acute Myeloid Leukemia Who Have Neither Favorable nor Unfavorable Markers

Alison R. Walker and Guido Marcucci

For patients with acute myeloid leukemia (AML), acquired chromosomal abnormalities present at diagnosis are the most important independent predictors of complete remission, disease-free survival, and overall survival. 1 - 3 Chromosomal analysis

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Strategy for Incorporating Molecular and Cytogenetic Markers into Acute Myeloid Leukemia Therapy

Mark G. Frattini and Peter G. Maslak

Edited by Kerrin G. Robinson

classification in older adults with acute myeloid leukemia (AML): analysis of 1065 patients entered into the United Kingdom Medical Research Council AML 11 trial . Blood 2001 ; 98 : 1312 – 1320 . 9. Chang C Storer B Scott B . Hematopoietic cell

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Acute Myeloid Leukemia: Selecting Induction Therapy Based on Biological Disease Factors

Presented by: Rebecca Olin

For patients with newly diagnosed acute myeloid leukemia (AML), leveraging cytogenetic, fluorescence in situ hybridization (FISH), and molecular genetic data plays a critical role in the selection of induction therapy. At the NCCN 2023 Annual

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Addressing Knowledge Gaps in Acute Myeloid Leukemia to Improve Referral for Hematopoietic Cell Transplantation Consultation

Christa Meyer, Lih-Wen Mau, Elizabeth A. Murphy, Ellen M. Denzen, Ellyce Hayes, Darlene Haven, Heather Moore, Jackie Foster, Jaime M. Preussler, and Linda J. Burns

Background Hematopoietic cell transplantation (HCT) is an underused therapy for patients with acute myeloid leukemia (AML). 1 Because HCT is performed only at select hospitals in the United States, it is critical to understand physician referral

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Novel Agents for the Treatment of Acute Myeloid Leukemia in the Older Patient

Maria R. Baer and Ivana Gojo

Acute Myeloid Leukemia Incidence Increases With Age The incidence of acute myeloid leukemia (AML) increases with age, with a median age at diagnosis of 67 years. 1 As the proportion of older adults in the population increases, AML in older

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Optimizing Therapy for Acute Myeloid Leukemia

Holbrook E. Kohrt and Steven E. Coutre

Dick JE . Acute myeloid leukemia . Hematology Am Soc Hematol Educ Program 2001 : 62 – 86 . 4. Appelbaum FR Gundacker H Head DR . Age and acute myeloid leukemia . Blood 2006 ; 107 : 3481 – 3485 . 5. Leith CP Kopecky KJ

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Treatment Updates in Acute Myeloid Leukemia

Presented by: Alexander E. Perl

“In the past few years, the NCCN Clinical Practice Guidelines in Oncology [NCCN Guidelines] for Acute Myeloid Leukemia [AML] have had some changes due to new drug approvals. This year, the updates are more incremental than revolutionary, but there

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NCCN Guidelines Insights: Acute Myeloid Leukemia, Version 2.2021

Featured Updates to the NCCN Guidelines

Daniel A. Pollyea, Dale Bixby, Alexander Perl, Vijaya Raj Bhatt, Jessica K. Altman, Frederick R. Appelbaum, Marcos de Lima, Amir T. Fathi, James M. Foran, Ivana Gojo, Aric C. Hall, Meagan Jacoby, Jeffrey Lancet, Gabriel Mannis, Guido Marcucci, Michael G. Martin, Alice Mims, Jadee Neff, Reza Nejati, Rebecca Olin, Mary-Elizabeth Percival, Thomas Prebet, Amanda Przespolewski, Dinesh Rao, Farhad Ravandi-Kashani, Paul J. Shami, Richard M. Stone, Stephen A. Strickland, Kendra Sweet, Pankit Vachhani, Matthew Wieduwilt, Kristina M. Gregory, Ndiya Ogba, and Martin S. Tallman

be able to: Integrate into professional practice the updates to the NCCN Guidelines for Acute Myeloid Leukemia Describe the rationale behind the decision-making process for developing the NCCN Guidelines for Acute Myeloid Leukemia Disclosure of

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Therapeutic Advances in First-Line Management of Acute Myeloid Leukemia

Daniel A. Pollyea

Introduction From the 1970s until 2017, there was little progress in the frontline treatment of acute myeloid leukemia (AML). Now, according to Daniel A. Pollyea, MD, MS, Associate Professor, University of Colorado School of Medicine, recent drug

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Novel and Emerging Treatment Strategies for Acute Myeloid Leukemia

Presented by: Eunice S. Wang

Despite the advent of novel targeted therapies and promising emerging strategies, acute myeloid leukemia (AML) remains difficult and challenging to treat. With a median age at diagnosis of 68 years, the incidence of AML is increasing as the general