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Evaluation of Pathologic Complete Response as a Surrogate for Long-Term Survival Outcomes in Triple-Negative Breast Cancer

Min Huang, Joyce O’Shaughnessy, Jing Zhao, Amin Haiderali, Javier Cortes, Scott Ramsey, Andrew Briggs, Vassiliki Karantza, Gursel Aktan, Cynthia Z. Qi, Chenyang Gu, Jipan Xie, Muhan Yuan, John Cook, Michael Untch, Peter Schmid, and Peter A. Fasching

4 RCTs, carboplatin in 3 RCTs, and nab-paclitaxel, everolimus, and anthracycline in 1 RCT each. Different pCR definitions were used across trials, of which ypT0/is ypN0 was the most common. The characteristics of the included trials are listed in

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Impact of Exercise on Chemotherapy Tolerance and Survival in Early-Stage Breast Cancer: A Nonrandomized Controlled Trial

Amy A. Kirkham, Karen A. Gelmon, Cheri L. Van Patten, Kelcey A. Bland, Holly Wollmann, Donald C. McKenzie, Taryne Landry, and Kristin L. Campbell

Baseline characteristics were compared between groups using independent t tests and chi-square tests. Relative risk (RR; with 95% confidence intervals and number needed to treat [NNT]) was used to compare categorical metrics of treatment tolerance

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Combined Androgen Blockade in Localized Prostate Cancer Treated With Definitive Radiation Therapy

Lucas K. Vitzthum, Chris Straka, Reith R. Sarkar, Rana McKay, J. Michael Randall, Ajay Sandhu, James D. Murphy, and Brent S. Rose

year before PCa diagnosis as previously described. 15 , 16 Table 1. Patient and Tumor Characteristics Information on treatment with ADT was obtained from the VA pharmacy database. CAB was defined as treatment with a nonsteroidal androgen receptor

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Racial Background and Health Behaviors Among Adults With Cancer in Canada: Results of a National Survey

Omar Abdel-Rahman

important to guide health authorities and practitioners to provide a personalized cancer survivorship message (according to individual characteristics) instead of the currently available generic messages and advice that do not take into consideration the

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A Routine Laboratory Data–Based Model for Predicting Recurrence After Curative Resection of Stage II Colorectal Cancer

Zhong Ye, Chun Wang, Limin Guo, Juan P. Palazzo, Zhixing Han, Yinzhi Lai, Jing Jiang, James A. Posey, Atrayee Basu Mallick, Bingshan Li, Li Jiang, and Hushan Yang

characteristic (ROC) curves and calculating the area under the curve (AUC). The prediction power was also estimated using Concordance-index (C-index), which works as an extension of AUC to the case of censored survival data. Patients with CRC were divided into

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Is Advanced Imaging in Early-Stage Breast Cancer Ever Warranted? Reconciling Clinical Judgment With Common Quality Measures

Arif Kamal, Tian Zhang, Steve Power, and P. Kelly Marcom

patients with cancer and the noncancer control population, a chi-square test was performed. Univariate logistic regression was used to determine patient and disease characteristics associated with the ordering of imaging. For determination of the attribute

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Use of Postprostatectomy Radiation Therapy at an NCI-Designated Comprehensive Cancer Center

Jeffrey M. Martin, Tianyu Li, Matthew E. Johnson, Colin T. Murphy, Alan G. Howald, Marc C. Smaldone, Alexander Kutikov, David Y.T. Chen, Rosalia Viterbo, Richard E. Greenberg, Robert G. Uzzo, and Eric M. Horwitz

univariate analyses were performed. Results From 2003 to 2011, 475 patients received PPRT at FCCC (83 adjuvant and 392 salvage). The patient characteristics and descriptives are listed in Table 1 . Patients were more likely to receive adjuvant RT if

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What the HEC? Clinician Adherence to Evidence-Based Antiemetic Prophylaxis for Highly Emetogenic Chemotherapy

Eric J. Roeland, Kathryn J. Ruddy, Thomas W. LeBlanc, Ryan D. Nipp, Gary Binder, Silvia Sebastiani, Ravi Potluri, Luke Schmerold, Eros Papademetriou, Lee Schwartzberg, and Rudolph M. Navari

We analyzed patient characteristics, HEC courses, and clinician practice patterns using descriptive statistics. Clinician HEC CINV prophylaxis adherence was categorized into deciles for each HEC, noting the clinicians with ≤90% adherence. Variability

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Beyond Median Overall Survival: Estimating Trends for Multiple Survival Scenarios in Patients With Metastatic Esophagogastric Cancer

Marieke Pape, Steven C. Kuijper, Pauline A.J. Vissers, Laurens V. Beerepoot, Geert-Jan Creemers, Hanneke W.M. van Laarhoven, and Rob H.A. Verhoeven

resection (resection of primary tumor ± perioperative treatment), chemoradiotherapy, systemic therapy, or BSC. Statistical Analysis Characteristics were noted with frequencies and percentages or mean and standard deviation. OS was assessed from the

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Patterns and Trends in Receipt of Opioids Among Patients Receiving Treatment for Cancer in a Large Health System

Lindsay M. Sabik, Kirsten Y. Eom, Zhaojun Sun, Jessica S. Merlin, Hailey W. Bulls, Patience Moyo, Jennifer A. Pruskowski, G.J. van Londen, Margaret Rosenzweig, and Yael Schenker

cancer diagnosis using chi-square tests. We then estimated multivariable logistic regression models to assess the association of patient characteristics, previous opioid receipt, treatment category, and year of diagnosis with receipt of an opioid